Casirivimab + Imdevimab

Dosage Forms Available

• Casirivimab + Imdevimab are available for administration through two primary routes: intravenous infusion and subcutaneous injection, which are administered in a hospital setting under the guidance of a doctor.

Age and Dose Restrictions

• Casirivimab + Imdevimab is intended for use in adults and pediatric patients who are 12 years of age and older and weigh at least 40 kg.

Contraindications

• There are no specific contraindications for Casirivimab + Imdevimab under normal conditions.

Other Medications to Avoid

• Casirivimab + Imdevimab may interact with other monoclonal antibodies (such as tocilizumab, and sarilumab), immunosuppressants (like corticosteroids, tacrolimus), and live attenuated vaccines (such as MMR). These interactions may affect the immune response and the effectiveness of treatment.

Overdose and Missed Dose

• In the event of an overdose of Casirivimab + Imdevimab, medical attention should be sought immediately, as the specific effects can vary and serious adverse reactions including anaphylaxis may occur.

• If a dose of Casirivimab + Imdevimab is missed, it should be administered as soon as possible when remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped to avoid potential overdose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For infusion-related reactions such as fever or chills during IV administration, pausing or slowing the infusion rate may help manage these symptoms.

• For injection site reactions such as redness or swelling from SC injections, applying a cold compress to the site after administration may provide relief.

Use in Driving and Operating Machinery

• Casirivimab + Imdevimab doesn't specifically impair driving or machinery use. However, if you feel dizzy after taking it, avoid these activities until the symptoms pass.

Use in Pregnancy and Lactation

• It is advisable to consult your doctor regarding its use during these conditions.

Caution in Other Conditions

• Patients with severe allergies or hypersensitivity to any component of this medication should exercise caution.

• Given that anaphylactic reactions have been observed with its use, it should be administered in settings where immediate treatment for severe reactions is available.

Special Dietary and Lifestyle Recommendations

• While taking Casirivimab + Imdevimab for COVID-19 management, maintaining a healthy lifestyle is crucial. This includes a balanced diet rich in fruits, vegetables, and lean proteins to support immune function.

• Staying hydrated by drinking plenty of water can help manage mild side effects such as headaches or dizziness.

• Ensuring adequate rest and avoiding excessive physical exertion can help your body focus on fighting off the infection.

• Practicing stress-reducing activities such as meditation or light yoga might also aid in overall well-being during treatment with this medication.