Cefoperazone + Tazobactam

Dosage Forms Available

• Cefoperazone + Tazobactam is administered through the intravenous route, meaning it is injected directly into a vein.

Age and Dose Restrictions

• It is intended for use in adults. The dosage varies based on the type and severity of the infection to be managed.

Contraindications

• This combination is contraindicated in patients with known hypersensitivity to either cefoperazone or tazobactam.

• It is also contraindicated in those with a known allergy to other beta-lactam antibiotics, such as penicillins or cephalosporins.

Other Medications to Avoid

• This combination can interact with aminoglycoside antibiotics (such as gentamicin and amikacin), anticoagulants (like warfarin and heparin), and gout medications (such as probenecid).

• It's also essential to avoid concurrent use of this combination with live bacterial vaccines (for example, typhoid vaccine).

Overdose and Missed Dose

• An overdose of Cefoperazone + Tazobactam can lead to nausea, vomiting, diarrhoea, and abdominal pain. If you suspect an overdose, please consult your doctor immediately.

• If you miss a dose of this medicine, consult your doctor for the next dose. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage diarrhoea and nausea associated with this medication.

Use in Driving and Operating Machinery

• It may cause drowsiness and dizziness. Avoid driving or operating heavy machinery while on this medication.

Use in Pregnancy and Lactation

• The safety of Cefoperazone + Tazobactam during pregnancy and breastfeeding is not well established. Therefore, it is advised to consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

• Patients with renal impairment should exercise caution when using this combination, as dosage adjustments may be necessary based on the creatinine clearance.

• Those with a history of gastrointestinal diseases, particularly colitis, should use this medicine with caution.

Special Dietary and Lifestyle Recommendations

• To prevent bacterial infections, maintain good hygiene practices such as regular hand washing.

• Consuming a balanced diet rich in fruits, vegetables, lean proteins, and whole grains can support overall health and immune function.