Aceclofenac
ANALGESICUses of Aceclofenac
- Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other musculoskeletal issues such as frozen shoulder and lower back pain.
- It helps improve mobility and reduce discomfort in chronic pain conditions.
Side effects of Aceclofenac
The side effects of Aceclofenac are:
- Indigestion
- Abdominal pain
- Nausea
- Diarrhoea
- Headache
- Dizziness
How Aceclofenac works
Aceclofenac works by inhibiting the action of cyclooxygenase (COX) enzymes, which play a key role in the synthesis of prostaglandins. Here's a more detailed look at how it functions:
- Aceclofenac inhibits the activity of both COX-1 and COX-2 enzymes. These enzymes are crucial in the biochemical pathway that converts arachidonic acid into prostaglandins.
- Prostaglandins are chemicals in the body that promote inflammation, pain, and fever. By blocking the COX enzymes, Aceclofenac reduces the production of prostaglandins.
- The reduction in prostaglandins leads to decreased inflammation and pain. This is particularly beneficial in conditions like arthritis, where inflammation is a significant source of pain.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Aceclofenac can be taken orally (tablet) and applied topically (gel). Tablet & Gel
Age and Dose Restrictions
- It should be given to children only if a child’s doctor recommends it.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to Aceclofenac. It is also contraindicated in patients with active peptic ulcers and in patients with a known history of asthma due to aspirin or other NSAIDs.
Medications to Avoid with This Drug
- Avoid taking antiarrhythmics (digoxin), diuretics, antihypertensive, anticoagulants, other NSAIDs, immunosuppressive medications (methotrexate and cyclosporine), quinolone antimicrobials, and antidiabetics. These medications may alter the safety and effectiveness of Aceclofenac.
Overdose and Missed Dose
- Overdose can cause headache, nausea, vomiting, abdominal pain, gastrointestinal irritation, and gastrointestinal bleeding. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
- If you miss a dose of Aceclofenac, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
Management of Side Effects
- Take this medicine with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use in Pregnancy and Lactation
- This medicine is not recommended during pregnancy, specifically during the third trimester. Caution is advised in breastfeeding women.
Caution in Other Conditions
- Caution is advised in older adults and patients with gastrointestinal disorders with a history of gastro ulceration, heart conditions, and kidney and liver impairment.
Special Dietary & Lifestyle Recommendation
- Avoid alcohol consumption, as it may increase the risk of adverse side effects.
- Excess weight can put a strain on joints and exacerbate pain. Aim to maintain a healthy weight through a balanced diet and regular exercise.
- Perform gentle stretches to improve flexibility and prevent muscle stiffness. Avoid overstretching, especially if you have an injury.
- You may apply a warm compress or ice pack to affected areas for relief from muscle spasms.
- Choose comfortable, supportive shoes to minimise the impact on joints and muscles.
Frequently asked questions
1. How much time does Aceclofenac take to work?
Aceclofenac typically show their effects within 30 minutes to an hour after ingestion. However, individual responses may vary.
2. Is Aceclofenac a habit-forming medicine?
Aceclofenac is not habit-forming and is generally safe when used as directed.
3. Can I drive after taking Aceclofenac?
Aceclofenac can make you feel dizzy. Do not drive, operate machinery, or do other activities that require mental alertness or coordination if you experience these side effects.
4. Does Aceclofenac affect fertility?
The use of this medicine may impair female fertility and is not recommended in women attempting to conceive.
5. Is Aceclofenac available over the counter, or do I need a prescription?
Aceclofenac usually requires a prescription and is not available over the counter.
6. Is Aceclofenac a strong painkiller?
Aceclofenac is a moderately strong pain reliever for musculoskeletal pain.
7. How long does the effect of Aceclofenac last?
Aceclofenac may relieve pain for up to a few hours. However, the duration of effect of this medication can vary with the individual and the severity of the condition being treated.
8. Is Aceclofenac a good painkiller?
Yes, Aceclofenac is a safe painkiller when consumed according to your doctor’s prescribed dosage and duration. It is commonly used to treat pain and inflammation associated with chronic bone and joint conditions. It belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs).
9. Does Aceclofenac get you high?
No, Aceclofenac does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.
10. Can Aceclofenac hurt your kidneys?
Long-term use and high doses of Aceclofenac may cause renal problems, such as protein or blood in urine and pain during urination. Patients with heart failure, impaired kidney function, and hypertension are at risk of kidney issues.
11. Does Aceclofenac make you drowsy?
You may experience drowsiness or sleepiness after taking Aceclofenac, although these side effects are very rare and do not affect many people. If you encounter these symptoms, avoid driving or operating heavy machinery. Also, avoid alcohol consumption while taking this medicine to prevent complications.
Aceclofenac in other salts
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