Adapalene
Uses of Adapalene
Adapalene is primarily used for the management of mild to moderate acne vulgaris. It is a topical retinoid medication and belongs to the group of medicines designed to manage acne.
Besides this primary use, Adapalene is particularly effective for comedonal acne, which is characterised by non-inflammatory lesions like blackheads and whiteheads. Additionally, it can also help manage inflammatory lesions like papules and pustules.
Side effects of Adapalene
Redness
Dryness
Scaling and peeling
Itching
Burning or stinging sensation
How Adapalene works
Adapalene is a member of the topical retinoid family of medications.
It works by binding to specific retinoic acid receptors (RARs) in the skin, leading to changes in gene expression. This action helps to regulate the turnover of skin cells and reduce inflammation. Adapalene also aids in loosening skin cells to unclog pores and decrease the build-up of dead skin cells. It reduces excess oil production from the sebaceous glands, which is a contributing factor in acne. With its anti-inflammatory properties, this medicine helps in decreasing redness, swelling, and irritation associated with acne lesions. Finally, it supports the natural exfoliation process of the outer layers of skin, promoting overall skin health.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Adapalene can be applied topically (gel, cream, and lotion).
Age and Dose Restrictions
Adapalene is typically recommended for individuals who are 12 years of age or older.
Contraindications
Adapalene should not be used by individuals who have a known allergy to the medication. It should also not be used on cuts, abrasions, eczematous, or sunburned skin.
Other Medications to Avoid
Adapalene may interact with other types of topical acne treatment (such as salicylic acid).
Overdose and Missed Dose
Overdose of Adapalene is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.
If you forget to apply Adapalene, do not double up the next day. Instead, continue with your regular once-daily application.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For dryness and irritation caused by using Adapalene, applying a non-comedogenic moisturiser can help.
Avoid using harsh skin care products like exfoliants, astringents, and alcohol-based products, as they can worsen irritation.
Use in Driving and Operating Machinery
Adapalene is a topical medication and does not influence your ability to drive or operate machinery.
Use in Pregnancy and Lactation
It is recommended to consult your doctor before using Adapalene during pregnancy or breastfeeding.
Caution in Other Conditions
Adapalene can make the skin more sensitive to weather extremes like wind and cold. If you have sensitive skin, start with the lower 0.1% strength and use it every other day to allow your skin to adjust.
Special Dietary and Lifestyle Recommendations
Avoid excessive sun exposure when using Adapalene since it can increase photosensitivity. Use sunscreen to protect your skin.
Maintain a skincare regime that includes gentle cleansing of acne-prone areas.
Stress management techniques can also be beneficial, as stress can sometimes trigger or worsen acne.
Frequently asked questions
Can Adapalene make the skin more sensitive to sunlight?
Yes, Adapalene can increase photosensitivity, meaning it can make your skin more sensitive to sunlight. Therefore, it is advised to avoid excessive sun exposure while using this medication and to use sunscreen.
What should I do if I experience severe allergic reactions while using Adapalene?
If you experience severe allergic reactions like swelling, difficulty breathing, or feeling faint after applying Adapalene, you should seek immediate medical attention.
Is Adapalene available over the counter, or do I require a prescription?
Adapalene is available both by prescription and over the counter in a 0.1% gel formulation.
What happens if I accidentally ingest Adapalene?
Accidental oral ingestion of Adapalene may lead to gastrointestinal symptoms and an increased risk of side effects. If this happens, seek medical help immediately.
Can I apply Adapalene on cuts or broken skin?
You should not apply Adapalene on cuts, abrasions, eczematous, or sunburned skin as it may cause further irritation or harm.
Can I wear makeup while using Adapalene?
Yes, but ensure the product has fully absorbed into the skin before you apply makeup. Use non-comedogenic, non-irritating cosmetics to avoid blocking pores.
Is Adapalene safe for long-term use?
Yes, Adapalene is safe for long-term acne management when used as prescribed by your doctor. Continuous use helps maintain clear skin.
Adapalene in other salts
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