Almotriptan is used for the acute management of migraine attacks with or without aura in adults. It is specifically a part of the group of medicines known as selective serotonin receptor agonists, also referred to as triptans.
It is not used for migraine prevention or to manage other types of headaches such as cluster headaches. Almotriptan should only be used where a clear diagnosis of migraine has been established by a doctor.
Nausea
Sleepiness or drowsiness
Tingling or numbness
Dizziness
Fatigue
Almotriptan is a selective serotonin receptor agonist, commonly known as a triptan.
It works by binding selectively to serotonin (5-HT1B/1D) receptors located on the blood vessels in the brain and sensory nerves. This action causes the blood vessels in the brain to constrict, reduces the release of pro-inflammatory substances from nerve endings, and blocks pain pathways. The result of this action is the relief of migraine pain and associated migraine symptoms such as nausea, vomiting, and sensitivity to light and sound. The overall effect is relief from an acute migraine attack.
Doctor of Medicine
BMS, FMC, MD Resident
Almotriptan is available in oral form for administration.
This medication comes as a tablet to take by mouth.
Almotriptan is intended for use in adults.
The medicine should not be administered to children or adolescents below 18 years of age.
Almotriptan is contraindicated in patients with a known hypersensitivity to the medicine.
Patients with ischemic heart disease, uncontrolled hypertension, or a history of stroke or transient ischemic attacks should also avoid using this medicine.
Almotriptan may interact with ergotamine-containing or ergot-type medicines (such as dihydroergotamine or methysergide), other 5-HT1 agonists, selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine, serotonin and norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine, and monoamine oxidase inhibitors (MAOIs) like phenelzine.
It is necessary to consult a doctor before beginning any new prescription or over-the-counter medications.
Overdose of Almotriptan can cause symptoms such as nausea, sleepiness, or heart problems. Seek immediate medical attention if you suspect an overdose.
If you miss a dose of Almotriptan, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage nausea, try eating light and bland meals.
If you experience dizziness or sleepiness, rest and avoid sudden changes in position.
Stay hydrated to help manage fatigue.
Almotriptan may cause dizziness or drowsiness, so it may affect your ability to drive or operate heavy machinery. It is advisable to avoid such activities until you know how this medicine affects you.
Almotriptan should only be used during pregnancy if the potential benefit justifies the potential risk to the foetus.
Nursing mothers should not breastfeed within 24 hours of taking Almotriptan.
Almotriptan should be used with caution in patients with risk factors for cardiovascular disease.
Patients with severe renal or hepatic impairment should also use Almotriptan cautiously.
Regular relaxation and mindfulness exercises may help manage stress, a common trigger for migraines.
Maintain a consistent sleep schedule to prevent triggering migraines.
Monitor your diet, as certain foods and drinks can trigger migraines. These might include alcohol, especially red wine, caffeine, chocolate, aged cheeses, monosodium glutamate (a flavour enhancer), and foods high in nitrates, like hot dogs and processed meats.
Keep a headache diary, noting when your migraines start, what you were doing at the time, how long they last and what, if anything, provides relief. Over time, you might identify specific foods, drinks, activity levels or changes in weather that trigger your migraines.
Frequently asked questions
No, Almotriptan is not a general painkiller. It is a specific medication used to manage acute migraine attacks in adults. It belongs to the class of medicines called selective serotonin receptor agonists (triptans).
Clinical trials have shown that Almotriptan starts to relieve migraine pain as early as 30 minutes after taking a 12.5 mg dose.
Yes, one of the common side effects of Almotriptan can be sleepiness or drowsiness. If this occurs, avoid driving or operating machinery until you know how it affects you.
If you are planning to become pregnant, consult your doctor before taking Almotriptan. It should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus.
Almotriptan generally starts working within 1 to 2 hours to relieve migraine symptoms. Individual responses may vary.
Almotriptan is typically used as needed at the onset of a migraine attack rather than taken every day. It should only be taken under the supervision of a doctor.
Almotriptan can be taken with or without food, but it may work faster if taken on an empty stomach.
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