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Ambroxol + Guaiphenesin

Cough Cold Preparation

Uses of Ambroxol + Guaiphenesin

  • Ambroxol + Guaiphenesin is used to treat productive cough linked to different respiratory disorders such as acute bronchitis, acute exacerbation of chronic bronchitis (AECB), pneumonia, and asthmatic bronchitis.

Side effects of Ambroxol + Guaiphenesin

  • Headache
  • Dizziness
  • Diarrhoea
  • Nausea
  • Vomiting

How Ambroxol + Guaiphenesin works

  • Ambroxol is known as a mucolytic agent, which means it helps to break down mucus. Excessive Nitric oxide (NO) in the airways can lead to inflammation and other issues. Ambroxol has been found to block the NO-driven activation of soluble guanylate cyclase. This inhibition might reduce the excessive production of mucus, thus lowering phlegm thickness and improving the movement of bronchial secretions.
  • Guaifenesin can irritate gastric receptors and trigger parasympathetic reflexes, leading to the release of thinner mucus from glands. This may induce coughing and help clear thick mucus from blocked airways, temporarily easing breathing difficulties.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

Ambroxol + Guaiphenesin is available for use via the oral route (syrup).

Age and Dose Restrictions

This medicine is meant for adults and children above 5 years of age.

Contraindications

This medicine is contraindicated in patients with known allergies to ambroxol and guaiphenesin.

Other Medications To Avoid With This Medicine

Ambroxol + Guaiphenesin can interact with antibiotics like erythromycin, doxycycline, cefuroxime, and amoxicillin. It can also interact with medicines with antitussive effects (for example, codeine-contained agents for cough) 

Overdose and Missed Dose

  • An overdose of this medicine may cause effects like nausea, vomiting, flush throat, and gastric/abdominal pain. If you detect an overdose of this medicine, inform your doctor and follow the advice accordingly.
  • If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.

Management Of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use In Driving And Operating Machinery

This medication may impair your ability to drive or operate machinery. If you experience any side effects that may alter your ability to drive, operate machinery, or perform any other tasks that require mental alertness, it is suggested to avoid these tasks.

Use in Pregnancy and Lactation

This medicine is not recommended in pregnancy and breastfeeding unless it is prescribed by your doctor.

Caution In Other Conditions

Patients with renal or hepatic conditions should exercise caution when taking this medicine.

Special Dietary & Lifestyle Recommendation

  • Avoid dairy products like milk, which can increase mucus. Avoid processed and refined foods. 
  • Instead, swap baked goods, fried foods, white bread, white pasta, sugary desserts, and chips for green leafy vegetables. 
  • Stay hydrated by drinking plenty of fluids to prevent a dry throat and help loosen mucus. 
  • Skip citrus fruits, as they can exacerbate coughing. Opt for fruits with high water content, such as pears, watermelon, peaches, and pineapples.

Frequently asked questions

This medicine's onset of action may require a few hours for full efficacy to be realised.

If you're allergic to this medicine, don't take it. Seek medical help right away if you have any allergic reactions. 

Please do not discontinue Ambroxol hydrochloride+ Guaiphenesin without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.

Patients with renal or hepatic conditions should exercise caution when taking this medicine.

There is not enough evidence to suggest that this medication affects your fertility, however, discuss it with your doctor before taking it

Terms & Conditions


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