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Ambroxol + Loratadine

Uses of Ambroxol + Loratadine

  • Ambroxol + Loratadine is primarily used for managing symptoms of respiratory tract disorders like acute and chronic bronchitis alongside allergic symptoms such as nasal discharge, itching, and sneezing. It belongs to the group of medications known as mucolytic agents and antihistamines.

Side effects of Ambroxol + Loratadine

  • Headache

  • Drowsiness

  • Fatigue

  • Dry mouth

  • Nausea

How Ambroxol + Loratadine works

  • Ambroxol + Loratadine is a combination medication comprising a mucolytic agent and an antihistamine.

  • Ambroxol works by breaking down the long chains of sugars in mucus, thereby reducing its stickiness. This makes the mucus thinner and easier to cough up. Furthermore, it boosts the production of a substance called pulmonary surfactant, which helps to keep the airways open, and stimulates fine hair-like structures (cilia) in the respiratory tract, aiding in the clearance of mucus.

  • Loratadine is an antihistamine specifically designed to target H1 receptors located outside the brain, thus minimising drowsiness. It operates by obstructing these receptors, providing relief from allergic symptoms like runny nose, sneezing, and itching caused by histamine, a substance released by the body during an allergic reaction.

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Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ambroxol + Loratadine is available in oral formulations.

  • The medicine can be taken as tablets or syrup. This facilitates ease of use depending on the patient’s preference and ability to swallow pills.

Age and Dose Restrictions

  • Ambroxol + Loratadine is suitable for adults and children.

  • It is not recommended for use in children under 2 years of age.

Contraindications

  • This medicine is contraindicated in patients with hypersensitivity to either ambroxol or loratadine.

  • It should also not be used by individuals with acute porphyria or severe hepatic impairment.

Other Medications to Avoid

  • Ambroxol + Loratadine combination may interact with antihistamines (such as diphenhydramine, chlorpheniramine), sedatives (such as diazepam, lorazepam), tricyclic antidepressants (such as amitriptyline, imipramine), beta-blockers (such as propranolol, atenolol), anticholinergic medications (such as atropine, ipratropium), and monoamine oxidase inhibitors (MAOIs) (such as phenelzine, tranylcypromine).

Overdose and Missed Dose

  • In cases of overdose, symptoms may include severe drowsiness, rapid heartbeat, and anticholinergic effects such as dry mouth or blurred vision. Immediate medical attention is advised to manage these symptoms effectively.

  • If you miss a dose of Ambroxol + Loratadine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dry mouth, sip water regularly or use sugar-free gum to stimulate saliva production.

  • If experiencing mild dizziness, ensure to sit or stand up slowly from lying positions.

Use in Driving and Operating Machinery

  • Ambroxol + Loratadine may cause drowsiness in some individuals.

  • It is advised to avoid driving or operating heavy machinery until you know how the medicine affects you.

Use in Pregnancy and Lactation

  • The use of this medicine during pregnancy or breastfeeding is not recommended without a doctor's advice. It is best to consult your doctor before taking this medication if you are pregnant or nursing.

Caution in Other Conditions

  • Caution is advised when using Ambroxol + Loratadine in patients with renal or hepatic impairment.

  • Adjustments to dosage or close monitoring may be necessary for safe use in these individuals.

Special Dietary and Lifestyle Recommendations

  • Increasing fluid intake can help manage respiratory conditions by keeping mucus thin and more manageable.

  • A humidifier in the sleeping area can also help by adding moisture to the air, which can help break down mucus.

  • Avoiding known allergens can significantly reduce symptoms of allergic rhinitis associated with respiratory issues.

  • Regular hand washing and avoiding close contact with people who are sick can prevent infections that might complicate respiratory conditions.

Frequently asked questions

No, Ambroxol + Loratadine is not a steroid. It is a combination medication that includes a mucolytic agent (ambroxol) and an antihistamine (loratadine).

Loratadine, a component of this combination, is a non-sedating antihistamine, which means it is less likely to cause drowsiness. However, some people may still experience drowsiness or fatigue as a side effect.

There is currently no scientific evidence indicating that Ambroxol + Loratadine adversely affects fertility. If you have concerns about fertility, please consult with your doctor.

There are no specific diet restrictions when taking this medication unless advised by your doctor. However, grapefruit juice may increase the plasma levels of ambroxol, so you may want to avoid consuming grapefruit while taking this medicine.

Ambroxol + Loratadine should only be taken as directed by your doctor. Do not exceed the recommended dose.

The time it takes for this medicine to work can vary among individuals and depends on various factors such as the individual's metabolism and the severity of symptoms.

The duration of treatment with this medicine should be as advised by your doctor.

Terms & Conditions


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