Ambroxol + Roxithromycin is primarily used to manage various respiratory conditions. It belongs to the group of mucolytic agents and macrolide antibiotics.
In addition to its use in managing acute and chronic bronchitis, community-acquired pneumonia, pharyngitis, tonsillitis and sinusitis, it is also used for conditions such as impetigo and urethritis.
Nausea
Vomiting
Diarrhoea
Stomach pain
Fatigue
Ambroxol + Roxithromycin is a respiratory medication combination.
Ambroxol is a mucolytic agent. It works by increasing the production of a substance called surfactant in the lungs and promoting the activity of tiny hair-like structures known as cilia. This helps to break down and clear mucus from the lungs, making it easier to cough up.
Roxithromycin is a macrolide antibiotic. It works by attaching itself to a specific part of bacteria called the 50S ribosomal subunit, which stops the bacteria from producing proteins essential for their growth and multiplication.
Together, these two components manage respiratory infections effectively by breaking down mucus and eliminating the bacteria causing the infection.
Doctor of Medicine
BMS, FMC, MD Resident
Dosage Forms Available
Ambroxol + Roxithromycin is available as an oral medication as tablets and syrups.
Age and Dose Restrictions
Ambroxol + Roxithromycin is typically prescribed for adults. The usage and dosage for children have not been firmly established yet, hence it should be given to children only under medical supervision.
Contraindications
Ambroxol + Roxithromycin is contraindicated if you have a known hypersensitivity to either Ambroxol, Roxithromycin, or any component of the formulation.
It is also contraindicated if you are taking ergot alkaloids due to the risk of ergot toxicity.
Other Medications to Avoid
Ambroxol + Roxithromycin may interact with several other medications. This includes bronchodilators (like ipratropium, theophylline), blood thinners (like warfarin, heparin) Ergot alkaloids (like ergotamine, ergometrine) and certain inhibitors and inducers of CYP3A4 (such as Ketoconazole, Itraconazole)
Before starting any new medication, whether prescription or over-the-counter, be sure to consult your doctor.
Overdose and Missed Dose
Overdosing on Ambroxol + Roxithromycin could lead to serious consequences such as severe allergic reactions or severe skin reactions. If you have taken too much of this medication, seek emergency medical attention immediately.
If you forget to take a dose of this medicine, take it as soon as you remember. However, if it is close to your next dose time, skip the missed dose and continue with your regular dosing schedule. Avoid doubling up on the dose.
Management of Side Effects
Most side effects of Ambroxol + Roxithromycin are temporary and will resolve once the medication is discontinued.
For common side effects such as nausea or stomach pain, try taking the medication with food.
Staying hydrated can help manage side effects such as diarrhoea.
Use in Driving and Operating Machinery
Ambroxol + Roxithromycin might cause dizziness or fatigue. If you experience these side effects, avoid driving or operating heavy machinery until you feel normal again.
Use in Pregnancy and Lactation
The safety of Ambroxol + Roxithromycin during pregnancy and lactation is not clearly established. Consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution in Other Conditions
Ambroxol + Roxithromycin should be used with caution in patients with liver or kidney impairment. Your doctor may need to adjust your dosage based on the severity of your condition.
Also, Roxithromycin may prolong the QT interval, so use cautiously if you have known QT prolongation or uncorrected hypokalemia.
Special Dietary and Lifestyle Recommendations
If you have been prescribed Ambroxol + Roxithromycin for respiratory conditions, it is advisable to avoid smoking and exposure to second-hand smoke.
Alcohol may worsen certain side effects of this medication, so it is recommended to limit your alcohol consumption while on this medication.
Regular deep breathing exercises can help improve lung function and manage respiratory symptoms more effectively.
Frequently asked questions
No, Ambroxol + Roxithromycin does not contain any steroids. It is a combination of a mucolytic agent and a macrolide antibiotic.
There is no known link between Ambroxol + Roxithromycin and sleep disturbances. However, individual reactions can vary, so if you experience any unusual sleep patterns after starting this medicine, please consult your doctor.
There is no established evidence to suggest that Ambroxol + Roxithromycin affects fertility. If you have any concerns regarding this, it is advisable to discuss them with your doctor.
There are no specific dietary restrictions while you are on Ambroxol + Roxithromycin unless your doctor advises otherwise.
Ambroxol + Roxithromycin should only be taken as prescribed by your doctor. Do not alter your dosage or take the medicine more often than recommended without consulting your doctor.
The time taken for Ambroxol + Roxithromycin to show its effects can vary depending on the severity of the condition it is being used to manage. Your doctor would be best placed to provide this information.
The best time to take Ambroxol + Roxithromycin would be as advised by your doctor, who will prescribe the dosing schedule based on your health condition and the severity of the infection.
Ambroxol + Roxithromycin in other salts
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