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Amitriptyline

ANTIDEPRESSANT

Uses of Amitriptyline

Amitriptyline is used to treat depression in adults. It is also sometimes used to treat chronic pain, anxiety, and trouble sleeping, though it’s not always the first choice for depression anymore. It can cause side effects, so it’s important to use it carefully.

Side effects of Amitriptyline

Constipation Dryness in mouth Orthostatic hypotension Weight gain Aggressive behaviour Nasal congestion Sleepiness Dizziness Headache Decreased libido Nausea Fatigue Confusion Tremors Speech disorder Palpitations Taste change Paresthesia Abnormality of voluntary movements Loss of accommodation Atrioventricular block Micturition disorders Erectile dysfunction Abnormal ECG The decreased sodium level in the blood

How Amitriptyline works

Amitriptyline comes into the tricyclic antidepressant category. It provides sedative and anticholinergic effects. It acts by inhibiting the reuptake and deactivation of the neurotransmitters noradrenaline and serotonin present at the nerve terminals in our brain. Reuptake inhibition of these monoamine neurotransmitters increases brain activity. This shows to be related to antidepressant action and benefits in mood regulation. It also prevents the transfer of pain signals from the nerves to the brain, so reducing neuropathy (pain from damaged nerves).

Certified content

Written By

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Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

You should take Amitriptyline for a specific duration of time and dose as your doctor recommends. You should not take it if you have ever had a drug dependency or abuse history. This medication may take two to four weeks to start functioning. Keep taking it exactly as prescribed. This medication medicine may cause weight gain and increased hunger; therefore, it is important to keep a close eye on your weight while you are taking it. Your blood pressure may drop quickly if you take this medication. If you have been seated or lying down, slowly rise to a standing position. Monitor any changes in behaviour, actions, thoughts, or emotions, especially if changes happen suddenly. This is important when starting treatment with an antidepressant or modifying the dosage of this medication. The following are some suggestions for maintaining a healthy lifestyle: Perform yoga daily. Get a good night's sleep. Limit your time spent on a computer or smartphone. Be sure to take your medicine at the prescribed times. This medication may cause dizziness and drowsiness. Do not operate a motor vehicle or engage in any activity requiring mental focus until you have determined how this medication will affect you. You should notify your doctor if you are pregnant, planning to become pregnant, or already breastfeeding. If you experience sudden mood swings or have suicidal thoughts, consult your doctor. Do not suddenly stop taking this medication medicine without consulting your doctor. If you are taking this medication, you should avoid drinking alcohol because it may cause you to feel sleepier or more drowsy than usual.

Frequently asked questions

No, using it during pregnancy may not be safe. Although there is a lack of information in human research, there is evidence from animal studies that this is harmful to a fetus. Your doctor will consider the risks and benefits before a prescription is given. Please consult your physician.

Within 2 to 4 weeks, you must experience the benefit of Amitriptyline.

No, it's likely unsafe to take Amitriptyline during breastfeeding. According to limited human data, the medicine may enter the breast milk and damage the unborn baby.

It is not recommended to use any pain relievers like tramadol, trazodone, hydrocodone, oxycodone, and acetaminophen, antidepressants like bupropion, duloxetine, fluoxetine, and sertraline, and antihistamines like cetirizine and diphenhydramine, sedatives like zolpidem, muscle relaxant like cyclobenzaprine, anti-convulsant like gabapentin, lamotrigine, escitalopram, pregabalin, and topiramate, anti-thyroid like levothyroxine, and anti-anxiety like alprazolam. Before using any prescription or over-the-counter medications, you must consult with your doctor.

Do not use this medicine if you have an allergic reaction (hypersensitivity) to any of its components. Do not take Amitriptyline if you consume alcohol. Due to a possible interaction, it may increase the chance of serious adverse effects. We recommend that you consult a doctor as soon as possible.

No, please do not stop taking Amitriptyline without first consulting your doctor. There is a chance that symptoms may return if it is suddenly stopped.

No, the use of this medicine will not lead to the development of any habitual actions. There have been no reports that withdrawal symptoms may appear when it is stopped. People in this situation can develop a psychological dependence on Amitriptyline medication if they continue to use it.

No, avoid consuming alcohol while taking the medicine because it could increase dizziness and drowsiness.

No, it is unlikely to affect fertility in either men or women. However, there is currently insufficient evidence to justify any clear conclusion. Consult your doctor for the most accurate information.

Yes, it's likely safe to take the medicine in kidney disease patients. No modification to the dosage is recommended. If you have any problems, you should consult your doctor.

Yes, Amitriptyline should be used with precaution, specifically if you have a history of liver disorders or problems. Some patients may need a dosage modification of the medicine. If you have any problems, you should consult your doctor.

Yes, it may cause dizziness. While using Amitriptyline, it is recommended that you should not drive or operate heavy machinery. It is suggested to relax until you feel better if you are experiencing sleep or dizziness.

Yes, one of the most common side effects of Amitriptyline is a headache. After taking Amitriptyline, if you have a headache, it is recommended that you take it easy for a moment.

Yes, using it can cause you to feel nausea and vomiting. If you vomit, take drinking water or other liquids continuously in small quantities. If you observe symptoms of dehydration, such as persistent vomiting, dark urine with a strong odour, or infrequent urination, consult with your doctor. Without first consulting, a doctor avoids taking any additional medications.

Yes, taking it frequently can cause dry mouth. If this side effect continues to disturb you, make an appointment with your doctor.

Terms & Conditions


Available medicines for AMITRIPTYLINE
Tryptinol 10 Tablet 10
Tryptinol 10 Tablet 10
Knoll Healthcare Pvt. Ltd.
Pack of 10 Units
₹12.55
MRP ₹25.15
50.10% OFF
Triptamin Mc 10 MG Tablet 10
Triptamin Mc 10 MG Tablet 10
El-dorado Bio-tech Pvt Ltd
Pack of 10 Units
₹73.21
MRP ₹89.28
18.00% OFF
Tryptomer 10mg Tablet 30
Tryptomer 10mg Tablet 30
Dr. Reddys Laboratories Ltd
Pack of 30 Units
₹61.71
MRP ₹75.26
18.00% OFF
Amitop 10mg Tablet 10
Amitop 10mg Tablet 10
Tas Med India Pvt Ltd
Pack of 10 Units
₹18.45
MRP ₹22.50
18.00% OFF
Tryptinol 25 Tablet 10
Tryptinol 25 Tablet 10
Knoll Healthcare Pvt. Ltd.
Pack of 10 Units
₹13.82
MRP ₹27.70
50.10% OFF
Aline 10 Tablet 10
Aline 10 Tablet 10
Marsha Pharma Pvt Ltd
Pack of 10 Units
₹19.47
MRP ₹23.74
18.00% OFF
Tryptomer 25mg Tablet 30
Tryptomer 25mg Tablet 30
Dr. Reddys Laboratories Ltd
Pack of 30 Units
₹60.89
MRP ₹74.26
18.00% OFF
Triptamin Mc 5 MG Tablet 10
Triptamin Mc 5 MG Tablet 10
El-dorado Bio-tech Pvt Ltd
Pack of 10 Units
₹65.60
MRP ₹80.00
18.00% OFF

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