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Amlodipine + Enalapril

Uses of Amlodipine + Enalapril

  • Amlodipine + Enalapril is primarily used to manage high blood pressure and certain types of chest pain (angina). It belongs to the group of medicines known as calcium channel blockers and ACE inhibitors.

Side effects of Amlodipine + Enalapril

  • Headache

  • Dizziness

  • Fatigue

  • Nausea

  • Diarrhoea

How Amlodipine + Enalapril works

  • Amlodipine + Enalapril is a combination medication for managing hypertension and angina.

  • Amlodipine is a calcium channel blocker. It works by blocking the entry of calcium into muscle cells in the heart and blood vessels. This relaxes and widens the blood vessels, increasing the supply of blood and oxygen to the heart while reducing its workload.

  • Enalapril is an angiotensin converting enzyme (ACE) inhibitor. It works by blocking an enzyme that is needed to produce a substance called angiotensin II. When angiotensin II is reduced, blood vessels can relax and widen, leading to lower blood pressure. Additionally, Enalapril reduces the secretion of another substance called aldosterone, which leads to increased excretion of sodium and water from the body.

  • Together, these two components help to effectively manage high blood pressure and reduce symptoms of chest pain by improving blood flow and reducing strain on the heart.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Amlodipine + Enalapril is available for oral consumption in tablet form.

Age and Dose Restrictions

  • Amlodipine + Enalapril is intended for use in adults and is not recommended for children under the age of 6 years.

Contraindications

  • Amlodipine + Enalapril is contraindicated in patients with a history of angioedema related to previous ACE inhibitor treatment.

  • It is also contraindicated in those with hereditary or idiopathic angioedema and those who are hypersensitive to any component of this combination.

Other Medications to Avoid

  • This combination may interact with aliskiren (a renin inhibitor), lithium (an antimanic agent), NSAIDs (like diclofenac), potassium supplements or potassium-sparing diuretics (like potassium chloride or amiloride), simvastatin (an HMG-CoA reductase inhibitor), and antidiabetic agents (like acarbose, miglitol).

Overdose and Missed Dose

  • An overdose may result in extreme dizziness, fainting, and fast or slow heartbeat. If an overdose occurs, seek emergency medical attention.

  • If you miss a dose, take it as soon as you remember, unless it is close to the time for your next dose. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • Adjust your position slowly when rising from a seated or lying position to manage lightheadedness or dizziness.

  • Stay well hydrated to help manage minor side effects like dry mouth or dehydration.

Use in Driving and Operating Machinery

  • This combination may cause dizziness or fatigue. It is advisable to avoid driving or operating heavy machinery until you know how this combination affects you.

Use in Pregnancy and Lactation

  • Amlodipine + Enalapril is contraindicated during pregnancy and should be discontinued as soon as pregnancy is detected. Its safety during lactation has not been established. Always consult your doctor before using this combination during breastfeeding.

Caution in Other Conditions

  • Caution is advised when using this combination in patients with severe aortic stenosis or hypertrophic cardiomyopathy owing to the risk of significant lowering of blood pressure.

  • Patients with kidney disorders or those undergoing dialysis should also exercise caution, as well as those with liver problems.

Special Dietary and Lifestyle Recommendations

  • Follow a heart-healthy diet low in salt, saturated fats, and cholesterol. Include plenty of fresh fruits, vegetables, and whole grains.

  • Regular physical activity can help maintain a healthy blood pressure level and improve heart health; aim for at least 30 minutes most days of the week.

  • Monitor your blood pressure regularly to check the effectiveness of your combination and lifestyle changes.

Frequently asked questions

No, it is not a steroid. It is a combination medicine belonging to the class of calcium channel blockers and ACE inhibitors.

Amlodipine + Enalapril can be taken with or without food. It should be taken as directed by your doctor.

Weight gain is not a typical side effect of taking this combination, but individual responses to medication can vary. If you notice significant weight gain while taking this combination, contact your doctor.

Yes, in rare cases, it may cause an allergic reaction, including symptoms like rash, hives, itching, and trouble breathing or swallowing. If any of these symptoms occur, seek medical help immediately.

There is no direct evidence to suggest that it has any significant effect on mood or hormones. However, If you experience any unusual changes in your mood or behaviour while taking this combination, consult your doctor.

It starts working soon after you take it, but it may take several weeks for this combination to have its full effect on lowering your blood pressure.

Even if you feel well, do not stop taking it without consulting your doctor. Hypertension often has no symptoms, and if you stop taking this combination, your condition could get worse.

Terms & Conditions


Available medicines for AMLODIPINE + ENALAPRIL
Amace Tablet 10
Amace Tablet 10
Systopic Laboratories Ltd-mem
Pack of 10 Units
₹74.62
MRP ₹91.00
18.00% OFF
Amena 5/5 MG Tablet 15
Amena 5/5 MG Tablet 15
Lanark Laboratories Pvt Ltd
Pack of 15 Units
₹36.90
MRP ₹45.00
18.00% OFF
Ampril 5/5 MG Tablet 10
Ampril 5/5 MG Tablet 10
Biogenetic Pharmaceuticals
Pack of 10 Units
₹28.70
MRP ₹35.00
18.00% OFF
Amlogen El 5/5 MG Tablet 10
Amlogen El 5/5 MG Tablet 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹25.42
MRP ₹31.00
18.00% OFF
Envas Am 2.5/5 MG Tablet 15
Envas Am 2.5/5 MG Tablet 15
Cadila Pharmaceuticals Ltd
Pack of 15 Units
₹36.88
MRP ₹44.97
18.00% OFF
Amtas E Tablet 15
Amtas E Tablet 15
Intas Pharmaceuticals Ltd
Pack of 15 Units
₹152.11
MRP ₹185.50
18.00% OFF
Envas Am 5/5 MG Tablet 15
Envas Am 5/5 MG Tablet 15
Cadila Pharmaceuticals Ltd
Pack of 15 Units
₹41.47
MRP ₹50.57
18.00% OFF
Hytrol Am 5/5 MG Capsule 10
Hytrol Am 5/5 MG Capsule 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹36.90
MRP ₹45.00
18.00% OFF

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