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Amlodipine + Valsartan

Uses of Amlodipine + Valsartan

  • The primary use of Amlodipine + Valsartan is to manage high blood pressure. It belongs to the categories of medicines known as Calcium Channel Blockers (CCBs) and Angiotensin II Receptor Blockers (ARBs).

Side effects of Amlodipine + Valsartan

  • Headache

  • Swelling in the hands, ankles, or feet

  • Dizziness

  • Fatigue

  • Nausea

How Amlodipine + Valsartan works

  • Amlodipine + Valsartan is a combination used to manage hypertension.

  • Amlodipine, a calcium channel blocker, works by preventing calcium from entering the muscle cells lining the blood vessels. This causes the blood vessels to relax and widen, making it easier for blood to flow through them, which in turn lowers the blood pressure.

  • Valsartan, an angiotensin II receptor blocker, acts by preventing a hormone called angiotensin II from narrowing the blood vessels. It thereby maintains an open and relaxed state of the blood vessels, reducing the workload on the heart and further lowering the blood pressure.

  • Together, Amlodipine and Valsartan provide effective management of high blood pressure by working in different but complementary ways to relax and open up the blood vessels.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Amlodipine + Valsartan is available in the form of oral tablets.

  • This combination medicine is meant to be taken by mouth.

Age and Dose Restrictions

  • This medicine is intended for use by adults only.

Contraindications

  • Amlodipine + Valsartan is contraindicated in patients with known hypersensitivity to amlodipine, valsartan, or any of the inactive components of the tablets.

  • It is also contraindicated in patients with severe hepatic impairment, biliary cirrhosis, and cholestasis.

Other Medications to Avoid

  • This combination may interact with aliskiren (such as Tekturna), ACE inhibitors (like lisinopril and ramipril), potassium-sparing diuretics (such as spironolactone and triamterene), NSAIDs (like ibuprofen and naproxen), simvastatin, CYP3A4 inhibitors (e.g., diltiazem, itraconazole, clarithromycin), and CYP3A4 inducers (e.g., rifampin, St. John's wort).

Overdose and Missed Dose

  • An overdose of Amlodipine + Valsartan may lead to severe hypotension (low blood pressure), dizziness, fainting, and possibly acute renal failure. If overdose symptoms occur, immediate medical intervention is required.

  • If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for the missed one.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dizziness or lightheadedness, it may help to get up slowly from a sitting or lying position.

  • Staying hydrated can help manage dizziness and fatigue associated with these medicines.

Use in Driving and Operating Machinery

  • This medication may impair your ability to drive or operate machinery. You should avoid driving or engaging in activities requiring alertness if you experience dizziness or sleepiness after taking this medication.

Use in Pregnancy and Lactation

  • Amlodipine + Valsartan is contraindicated during pregnancy due to the risk of harm to the foetus. It should not be used during breastfeeding as it is unknown if the components pass into breast milk.

  • It is crucial to consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with renal impairment or those at risk for electrolyte imbalances should exercise caution when taking Amlodipine + Valsartan.

  • Individuals with dehydration or those undergoing major surgery that involves substantial fluid shifts should also be cautious.

Special Dietary and Lifestyle Recommendations

  • Maintain a low-sodium diet to help manage hypertension effectively. Avoid high-salt foods such as processed meats, canned soups, and fast foods.

  • Incorporate potassium-rich foods like bananas, oranges, and leafy greens into your diet unless otherwise advised by your doctor.

  • Regular physical activity such as walking, cycling, or swimming can help lower blood pressure.

  • Monitor weight regularly to ensure healthy body weight maintenance which supports blood pressure management.

  • Manage stress through relaxation techniques like yoga, meditation, or deep breathing exercises.

Frequently asked questions

No, Amlodipine + Valsartan is not a steroid. It is a combination of two medicines used to manage high blood pressure.

No typical mood-related side effects have been reported with Amlodipine + Valsartan. However, if you experience any unusual changes in mood or behaviour while taking this medication, report it to your doctor.

Weight gain is not a typical side effect of Amlodipine + Valsartan. However, some people may experience swelling in the hands, ankles or feet which could be mistaken for weight gain.

Although there are no known interactions between Amlodipine + Valsartan and orange juice, it is always safe to consult your doctor before making any changes to your diet or medication regimen.

The individual medicines in the Amlodipine + Valsartan combination start working within a few hours of taking the dose. However, full blood pressure control may take several weeks.

Dizziness is a common side effect of Amlodipine + Valsartan, which some people may interpret as drowsiness. If you experience severe drowsiness or dizziness, please inform your doctor.

Swelling in the hands, ankles, or feet can be a side effect of Amlodipine + Valsartan. If you experience such symptoms, it is important to consult your doctor immediately.

Terms & Conditions


Available medicines for AMLODIPINE + VALSARTAN
Amlopres Vl 5/160 MG Tablet 10
Amlopres Vl 5/160 MG Tablet 10
Cipla Ltd.
Pack of 10 Units
₹78.92
MRP ₹96.25
18.00% OFF
Valembic Am 5/160 MG Tablet 10
Valembic Am 5/160 MG Tablet 10
Alembic Ltd
Pack of 10 Units
₹78.56
MRP ₹95.80
18.00% OFF
Valsator Am Tablet 10
Valsator Am Tablet 10
Prevego Healthcare & Research Pvt.ltd.
Pack of 10 Units
₹62.25
MRP ₹110.00
43.40% OFF
Valzaar Sm 2.5/80 MG Capsule 10
Valzaar Sm 2.5/80 MG Capsule 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹121.36
MRP ₹148.00
18.00% OFF
Amlopres Vl 5/80 MG Tablet 10
Amlopres Vl 5/80 MG Tablet 10
Cipla Ltd.
Pack of 10 Units
₹51.29
MRP ₹62.55
18.00% OFF
Exforge 5 MG Tablet 14
Exforge 5 MG Tablet 14
Novartis India Ltd
Pack of 14 Units
₹637.07
MRP ₹776.92
18.00% OFF
Valembic 80 Am Tablet 10
Valembic 80 Am Tablet 10
Alembic Ltd
Pack of 10 Units
₹73.39
MRP ₹89.50
18.00% OFF

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