Amoxicillin + Clarithromycin + Esomeprazole

Dosage Forms Available

• Amoxicillin + Clarithromycin + Esomeprazole is available for oral administration as capsules.

Age and Dose Restrictions

• This medicine is meant for adults aged 18 years and above.

Contraindications

• This combination medicine is not advisable for patients with known hypersensitivity to any of its components, Amoxicillin, Clarithromycin, or Esomeprazole.

• It is also contraindicated for patients with a history of hepatic dysfunction or cholestatic jaundice associated with prior clarithromycin use.

Other Medications to Avoid

• This combination may interact with strong CYP3A4 inhibitors (such as ketoconazole, itraconazole, ritonavir etc), benzodiazepines (like alprazolam, diazepam), and anticoagulants (for example, warfarin).

Overdose and Missed Dose

• Overdosage with this medicine might lead to symptoms which are generally consistent with those of its individual components. There is no specific antidote. In case of an overdose, symptomatic and supportive treatment should be administered.

• If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

• Drinking plenty of water can help manage gastrointestinal side effects like diarrhoea and abdominal pain.

• Taking the medication with meals may help reduce nausea and vomiting.

Use in Driving and Operating Machinery

• The combination medication may cause dizziness or tiredness. If affected, avoid driving or operating machinery until you feel well enough.

Use in Pregnancy and Lactation

• This combination medicine should only be used during pregnancy or lactation if prescribed by your doctor.

Caution in Other Conditions

• Patients with a history of liver or kidney problems should use this medicine with caution, as it can affect liver and kidney functions.

Special Dietary and Lifestyle Recommendations

• Adopting a balanced diet can help manage the underlying conditions for which this medicine is used. Include plenty of fruits, vegetables, lean proteins, and whole grains.

• Limit intake of spicy and fatty foods, which can aggravate stomach problems.