Amoxicillin + Clarithromycin + Pantoprazole

Dosage Forms Available

• Amoxicillin + Clarithromycin + Pantoprazole is available in the form of tablets. This medicine is used via the oral route.

Age and Dose Restrictions

• This medicine is meant for adults.

Contraindications

• This medicine is contraindicated in patients with known allergies to amoxicillin, clarithromycin, or pantoprazole.

• It should not be used by patients with a history of cholestatic jaundice or hepatic dysfunction associated with prior clarithromycin use.

• The combination therapy is also contraindicated in severe hepatic impairment and those taking rilpivirine-containing products.

Other Medications to Avoid

• Amoxicillin + Clarithromycin + Pantoprazole may interact with allopurinol (like Zyloprim and Lopurin), oral contraceptives (such as Ethinylestradiol + Levonorgestrel), probenecid (such as Probalan), and medicines metabolised by CYP2C19 (e.g., clopidogrel and citalopram).

Overdose and Missed Dose

• Overdosing on this medication could lead to serious health complications. In such instances, immediate medical help should be sought. Vital signs monitoring and supportive care are important in managing an overdose situation.

• If you miss a dose, take it as soon as you remember, unless it's nearly time for your next dose. Avoid doubling up on doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage some side effects like dry mouth and constipation.

• Taking this medication with food can reduce the occurrence of stomach discomfort or nausea.

Use in Driving and Operating Machinery

• This medicine may cause dizziness or disorientation. If you experience these side effects, avoid driving or operating heavy machinery until you feel able to perform these tasks safely.

Use in Pregnancy and Lactation

• Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

Caution in Other Conditions

• This medicine should be used with caution in patients with severe hepatic impairment due to the presence of clarithromycin.

• Caution is also advised in patients who have a known history of hypersensitivity reactions to any of the individual components of this combination.

• This combination should be used with caution in patients with severe renal impairment. 

Special Dietary and Lifestyle Recommendations

• A diet rich in fiber may help manage potential gastrointestinal issues associated with this medicine.

• Regular rest is important as this medicine may sometimes cause dizziness or disorientation.

• A balanced diet along with regular exercise, can also help improve overall health and well-being.