Aspirin + Isosorbide-5-mononitrate / Isosorbide Mononitrate

Dosage Forms Available

• Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate is available for use in the form of oral tablets.

Age and Dose Restrictions

• This combination medication is generally recommended for adults. It may also be used in adolescents and children, but only under the close supervision of a doctor.

Contraindications

• Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate is contraindicated in patients with known allergies to either aspirin or isosorbide mononitrate.

• The use of this medication is also contraindicated in patients with active peptic ulcer disease, severe liver impairment, severe kidney impairment, low blood pressure, and decreased blood volume.

Other Medications to Avoid

• Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate may interact with blood thinners (such as warfarin, heparin), other antiplatelet agents (like clopidogrel, ticlopidine), nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen)

• Before starting any new prescription medicine or over-the-counter medicine, please consult your doctor.

Overdose and Missed Dose

• An overdose of Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate can lead to symptoms such as ringing in the ears, rapid or deep breathing, fever, confusion, seizures, and coma. In such a case, seek immediate medical attention.

• If you happen to miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage some of the gastrointestinal side effects such as nausea and stomach pain.

• To manage the side effect of dizziness, it is advised to rise slowly from a sitting or lying position.

Use in Driving and Operating Machinery

• Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate can cause dizziness or light-headedness. Therefore, avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

• Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate should be used during pregnancy only if clearly needed and under the supervision of a doctor.

• As aspirin is excreted in breast milk, breastfeeding while taking this medication is not recommended.

Caution in Other Conditions

• Patients with severe anaemia, hyperthyroidism, and glaucoma should use Aspirin + Isosorbide-5-Mononitrate / Isosorbide Mononitrate with caution.

Special Dietary and Lifestyle Recommendations

• Following a balanced diet rich in fruits, vegetables, whole grains, lean proteins and low-fat dairy can help in managing angina pectoris due to coronary artery disease.

• Quitting smoking and restricting alcohol intake can lower risk factors associated with heart disease.

• Regular physical activity can help keep your heart healthy. However, it's essential to talk to your doctor about the type and amount of exercise that is suitable for you.

• Stress management is crucial as stress can trigger angina pain. Relaxation techniques such as deep breathing, yoga, and meditation can help manage stress levels.

• Regular check-ups and following the medication plan as prescribed by the doctor is crucial for managing the underlying disease effectively.