Atorvastatin + S-amlodipine
Uses of Atorvastatin + S-amlodipine
The primary use of Atorvastatin + S-Amlodipine is to manage hypertension in patients who also have high cholesterol. This combination belongs to the group of anti-hypertensive and lipid-lowering medications.
It is particularly beneficial for patients with multiple risk factors for coronary heart disease but without clinically evident coronary heart disease. The medication helps prevent serious cardiovascular events in patients with diabetes and coronary heart disease risk factors.
Side effects of Atorvastatin + S-amlodipine
Headache
Dizziness
Fatigue
Nausea
Abdominal pain
How Atorvastatin + S-amlodipine works
Atorvastatin + S-Amlodipine is categorized as a combination of a statin and a calcium channel blocker.
Atorvastatin works by inhibiting an enzyme in the liver called HMG-CoA reductase. This enzyme is vital for making cholesterol. By blocking this enzyme, Atorvastatin reduces LDL ("bad") cholesterol and triglycerides, while increasing HDL ("good") cholesterol levels.
S-Amlodipine is a calcium channel blocker. It operates by blocking the influx of calcium into the smooth muscle cells of the heart and arteries. This action relaxes and widens blood vessels, reducing the workload on the heart and ultimately lowering blood pressure.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Atorvastatin + S-Amlodipine is available for oral administration in the form of tablets.
Age and Dose Restrictions
This medicine is intended for use by adults and adolescents above 12 years of age.
Contraindications
Atorvastatin + S-Amlodipine is contraindicated in patients with known hypersensitivity to either Atorvastatin or S-Amlodipine. The medicine is also contraindicated in individuals with active liver disease, or unexplained persistent increases in serum transaminases.
Other Medications to Avoid
Atorvastatin + S-Amlodipine may interact with medications such as other calcium channel blockers (like diltiazem), antifungal agents (such as itraconazole), and certain antibiotics (like clarithromycin).
Overdose and Missed Dose
An overdose of this combination may result in complications like extreme dizziness, irregular heartbeat, severe nausea or diarrhoea. Immediate medical attention should be sought in case of suspected overdose.
If you miss a dose of this medication, it should be taken as soon as remembered. However, if it is close to the next dose, the missed dose should be skipped.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage some side effects like constipation.
Taking the medication with food can help manage nausea.
Use in Driving and Operating Machinery
This combination medicine may cause dizziness or sleepiness. It is advised not to drive or operate machinery until you know how this medicine affects you.
Use in Pregnancy and Lactation
Atorvastatin + S-Amlodipine is not recommended during pregnancy and breastfeeding unless advised by a doctor.
Caution in Other Conditions
Patients with renal impairment, severe hypotension, aortic stenosis, or severe heart failure should exercise caution when taking Atorvastatin + S-Amlodipine.
Special Dietary and Lifestyle Recommendations
A low cholesterol, low salt diet can help manage the conditions for which Atorvastatin + S-Amlodipine is indicated.
Regular physical activity can also help control blood pressure and cholesterol levels.
It is recommended to avoid smoking and limit alcohol consumption as these habits can increase your risk of heart disease.
Frequently asked questions
Is Atorvastatin + S-Amlodipine a steroid?
No, Atorvastatin + S-Amlodipine is not a steroid. Atorvastatin belongs to a group of medications known as statins or HMG-CoA reductase inhibitors and S-Amlodipine is a calcium channel blocker.
Does Atorvastatin + S-Amlodipine have any effect on sleep?
Atorvastatin + S-Amlodipine is not typically associated with effects on sleep. However, if you experience unusual sleep patterns after starting this medication, please consult your doctor.
Will Atorvastatin + S-Amlodipine affect fertility?
Atorvastatin + S-Amlodipine does not typically affect fertility. However, if you have concerns about fertility, it is advisable to discuss this with your doctor.
Is it safe to take Atorvastatin + S-Amlodipine daily?
It is safe to take Atorvastatin + S-Amlodipine daily, as prescribed by your doctor. The dosage and duration of treatment will depend on individual patient response and tolerability.
How much time does Atorvastatin + S-Amlodipine take to work?
The time taken for Atorvastatin + S-Amlodipine to show its effect may vary depending on individual patient response. You should continue taking the medication as directed by your doctor.
What is the best time to take Atorvastatin + S-Amlodipine?
Atorvastatin + S-Amlodipine can be taken at any time of the day, with or without food. However, it is recommended to take it at the same time each day for better efficacy.
Are there any natural alternatives to Atorvastatin + S-Amlodipine?
While certain dietary changes and exercises can aid in managing high blood pressure and high cholesterol levels, they may not substitute the need for a medication like Atorvastatin + S-Amlodipine. Always consult your doctor before making any changes to your medication routine.
Atorvastatin + S-amlodipine in other salts
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