Azithromycin + Ofloxacin
Uses of Azithromycin + Ofloxacin
The main use of the combination of Azithromycin + Ofloxacin is to manage various bacterial infections; it is part of the macrolide and fluoroquinolone classes of antibiotics.
It is also used in handling community-acquired pneumonia, complicated urinary tract infections, pelvic inflammatory disease, skin and soft tissue infections, acute bacterial sinusitis, and sexually transmitted infections like gonorrhoea and chlamydia.
Side effects of Azithromycin + Ofloxacin
Nausea
Vomiting
Diarrhoea
Abdominal pain
Skin rash
How Azithromycin + Ofloxacin works
Azithromycin + Ofloxacin belongs to the category of antibacterial medications.
Azithromycin is a macrolide antibiotic that inhibits bacterial protein synthesis. It attaches to the 50S subunit of the bacterial ribosome, preventing the formation of peptides.
Ofloxacin, a fluoroquinolone antibiotic, blocks bacterial DNA synthesis. It directly targets DNA gyrase and topoisomerase IV, essential enzymes for bacteria to copy, repair, and rearrange their DNA. By disrupting these functions, ofloxacin hinders the survival and reproduction of bacteria. The dual action of Azithromycin + Ofloxacin on different bacterial functions enhances their effectiveness against a wide variety of bacteria. They work in harmony to halt bacterial growth through multiple mechanisms.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Azithromycin + Ofloxacin is available in the form of oral tablets.
Age and Dose Restrictions
This medicine is designed for adult usage and should be given to children under the age of 18 only if prescribed by a doctor.
Contraindications
Azithromycin + Ofloxacin is contraindicated for individuals who have a known allergy to either azithromycin or ofloxacin.
It should also not be used in patients with myasthenia gravis, a condition causing muscle weakness.
Other Medications to Avoid
Azithromycin + Ofloxacin may interact with anticoagulants (such as warfarin) and cardiac glycosides (like digoxin).
Overdose and Missed Dose
An overdose of Azithromycin + Ofloxacin could have severe consequences including abdominal pain, nausea, vomiting, and diarrhoea. In extreme cases, it could lead to seizures. If an overdose is suspected, it is crucial to seek immediate medical attention.
If a dose of this medicine has been missed, it should be taken as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your normal dosing schedule. It is not advised to take double doses to make up for a missed one.
Management of Side Effects
Most side effects of Azithromycin + Ofloxacin are temporary and disappear when you stop taking the medicine. However, if severe side effects persist, consult your doctor immediately.
Drinking plenty of water may help manage mild side effects like nausea and diarrhoea.
Taking this medication with food can help manage stomach upsets.
Use in Driving and Operating Machinery
Azithromycin + Ofloxacin may cause drowsiness or dizziness. It is advisable to avoid driving or operating heavy machinery if you experience these side effects after taking this medicine.
Use in Pregnancy and Lactation
The use of Azithromycin + Ofloxacin during pregnancy or lactation should be avoided unless necessary and recommended by a doctor.
Caution in Other Conditions
Caution is advised when using Azithromycin + Ofloxacin in patients with heart rhythm disorders, liver disease, kidney disease, or in individuals with a history of tendon disorders or nerve damage.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to boost your body's ability to fight infections.
Limit your intake of sugary drinks and junk food as they can lead to inflammation and potentially disrupt your body’s ability to ward off infection.
Frequently asked questions
Is Azithromycin + Ofloxacin a steroid?
No, Azithromycin + Ofloxacin is not a steroid. They are antibiotics used to manage bacterial infections.
Does Azithromycin + Ofloxacin have any effect on sleep?
The combination of Azithromycin + Ofloxacin does not typically affect sleep. However, if you experience unusual sleep patterns while using this medication, consider consulting your doctor.
Will Azithromycin + Ofloxacin affect fertility?
Azithromycin + Ofloxacin is not associated with impacting fertility in men or women. However, serious infections can interfere with overall health and fertility, so ensuring adequate treatment is essential.
Is it safe to take Azithromycin + Ofloxacin daily?
Azithromycin + Ofloxacin should be taken as per the dosage and duration recommended by your doctor.
How much time does Azithromycin + Ofloxacin take to work?
Azithromycin + Ofloxacin starts working soon after taking the dose, but the complete effect may be visible after a few days of regular use.
What is the best time to take Azithromycin + Ofloxacin?
The best time to take Azithromycin + Ofloxacin is as prescribed by your doctor.
Is Azithromycin + Ofloxacin a vegetarian medicine?
Azithromycin + Ofloxacin is a synthetic antibiotic and does not contain any animal-derived ingredients. However, the capsule or tablet form may sometimes have gelatin, which is animal-derived. It is better to check with the manufacturer for specific details.
Azithromycin + Ofloxacin in other salts
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