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Bempedoic Acid

Uses of Bempedoic Acid

  • Bempedoic Acid is mainly used to manage primary hypercholesterolemia (a condition where blood cholesterol levels exceed normal limits) or mixed dyslipidemia in adults when statins are intolerable for managing the condition. It belongs to the class of medicines known as ACL inhibitors.

Side effects of Bempedoic Acid

  • Anaemia
  • Elevated levels of uric acid levels in the blood (gout)
  • Pain in arms, legs, shoulders
  • Blood tests showing liver abnormalities
  • Decreased GF

How Bempedoic Acid works

  • Bempedoic Acid is an adenosine triphosphate-citrate lyase (ACL) inhibitor.

  • It works by inhibiting ATP citrate lyase, an enzyme crucial for synthesizing cholesterol, particularly low-density lipoprotein (LDL or "bad" cholesterol). This inhibition promotes increased uptake and clearance of LDL in the liver, leading to reduced total blood cholesterol levels.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Bempedoic Acid is available in tablet form for oral administration.

Age and Dose Restrictions

  • This medication is meant for adults only. It is not recommended for use in children or adolescents below 18 years of age.

Contraindications

  • This medication is contraindicated in patients with a known hypersensitivity to bempedoic acid or any other constituents of this medicine.

Other Medications to Avoid

  • Bempedoic Acid may interact with statins (e.g., simvastatin, pravastatin), which are used to manage high cholesterol levels. It may also interact with medicines used to manage pulmonary artery hypertension (e.g., bosentan), medicines used to manage high blood pressure and heart failure (e.g., fimasartan), and medicines used to manage hepatitis C (e.g., asunaprevir, glecaprevir, grazoprevir, voxilaprevir).

Overdose and Missed Dose

  • An overdose of this medicine can lead to the risk of developing unwanted side effects. If you suspect an overdose, you should immediately consult your doctor.
  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once to make up for a missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve upon discontinuation of this medicine. However, if you experience any severe side effects or worsening of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage some of the side effects like dry mouth and constipation.
  • Taking this medicine with food may help reduce gastrointestinal side effects like stomach upset.

Use in Driving and Operating Machinery

  • This medicine does not typically affect your ability to drive or operate machinery. However, if you experience side effects like dizziness after taking this medication, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • This medicine is not recommended during pregnancy and lactation unless necessary. If you are pregnant or breastfeeding, consult your doctor before using this medicine.

Caution in Other Conditions

  • Patients with a history of gout or elevated uric acid levels should exercise caution when using Bempedoic Acid, as it may exacerbate these conditions.
  • Individuals with a tendency towards tendon injuries or existing tendon disorders should also be cautious.

Special Dietary and Lifestyle Recommendations

  • Maintaining a healthy diet low in saturated fats and cholesterol can aid the effectiveness of Bempedoic Acid in managing high cholesterol levels.
  • Regular physical activity is important for maintaining cardiovascular health and supporting the management of high cholesterol.

Frequently asked questions

No, it is not related to steroids. It belongs to a group of medicines known as ACL inhibitors.

There is no evidence suggesting that it directly influences sleep patterns. However, as with any medication, individual reactions may vary. If you experience any unusual sleep disturbances, consult your doctor.

The research does not suggest that it can affect fertility in men or women. If you have concerns about fertility, it is best to discuss this with your doctor before starting the medication.

No specific diet restrictions are associated with the use of Bempedoic Acid. Nonetheless, a heart-healthy diet is often recommended alongside the medicine to maximise its effect in reducing LDL cholesterol levels.

It is typically suitable for vegetarians and vegans. However, it is always best to consult your doctor or pharmacist to confirm.

The time taken for this medicine to show its effect can vary based on individual factors such as age, metabolism, and severity of the condition. You should consult your doctor for specific details.

It can be taken at any time of the day, with or without food. However, it is usually recommended to take it at the same time each day for maximum effectiveness.

Terms & Conditions


Available medicines for BEMPEDOIC ACID
Bemzire Tablet 10
Bemzire Tablet 10
La Renon
Pack of 10 Units
â‚ą168.92
MRP â‚ą206.00
18.00% OFF
Brillo Tablet 10
Brillo Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
â‚ą215.66
MRP â‚ą263.00
18.00% OFF
Nudoic Tablet 10
Nudoic Tablet 10
Macleods Pharmaceuticals Pvt.ltd
Pack of 10 Units
â‚ą196.80
MRP â‚ą240.00
18.00% OFF
Bempify Tablet 10
Bempify Tablet 10
Lupin Ltd
Pack of 10 Units
â‚ą196.80
MRP â‚ą240.00
18.00% OFF
Embia Tablet 10
Embia Tablet 10
Ajanta Pharma Ltd
Pack of 10 Units
â‚ą196.80
MRP â‚ą240.00
18.00% OFF
Bempesta Tablet 10
Bempesta Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
â‚ą215.50
MRP â‚ą262.80
18.00% OFF
Nexred Tablet 10
Nexred Tablet 10
Dr. Reddys Laboratories Ltd
Pack of 10 Units
â‚ą252.56
MRP â‚ą308.00
18.00% OFF
Bemdac Tablet 10
Bemdac Tablet 10
Zydus Healthcare Ltd
Pack of 10 Units
â‚ą216.48
MRP â‚ą264.00
18.00% OFF

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