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Bempedoic Acid + Ezetimibe

Uses of Bempedoic Acid + Ezetimibe

  • Bempedoic Acid + Ezetimibe is most commonly used to lower levels of LDL (low-density lipoprotein) cholesterol in the blood and it belongs to the category of cholesterol-lowering medications.
  • Additionally, it may be prescribed for adults with established cardiovascular disease (CVD) or heterozygous familial hypercholesterolemia (HeFH) who require additional lowering of LDL cholesterol.

Side effects of Bempedoic Acid + Ezetimibe

  • Muscle pain or weakness
  • Inflammation of the nasal passages and throat
  • Nausea
  • Back pain
  • Abdominal pain or discomfort

How Bempedoic Acid + Ezetimibe works

  • Bempedoic Acid + Ezetimibe is a cholesterol-lowering combination.
  • Bempedoic Acid is an ATP citrate lyase inhibitor. It works by blocking an enzyme in the liver that is necessary for making cholesterol, effectively reducing the amount of LDL (low-density lipoprotein or "bad" cholesterol) produced by the body.
  • Ezetimibe is a cholesterol absorption inhibitor. It acts in the small intestine and hinders a particular protein that aids in moving cholesterol into the cells lining the intestines. By doing this, it reduces the amount of cholesterol absorbed from your diet.
  • When used together, these two components perform a dual role - reducing the production of cholesterol in the body and limiting its absorption from food, thereby effectively managing high levels of LDL cholesterol in the blood.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Bempedoic Acid + Ezetimibe is available as oral tablets.

Age and Dose Restrictions

  • This medicine is meant for adult use only and is suitable for patients who are above the age of 18 years.

Contraindications

  • This medicine is contraindicated in patients with moderate to severe hepatic impairment.
  • It is also contraindicated for individuals with a known hypersensitivity to either Bempedoic acid or Ezetimibe.

Other Medications to Avoid

  • This combination may interact with other cholesterol-lowering agents (such as simvastatin and pravastatin), immunosuppressants (including cyclosporine), and bile acid sequestrants (like cholestyramine).

Overdose and Missed Dose

  • An overdose of Bempedoic Acid + Ezetimibe may lead to increased side effects such as muscle pain or weakness. If you suspect an overdose, it is important to seek immediate medical attention.
  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage minor gastrointestinal discomfort, taking the medication with food may help alleviate symptoms.
  • Staying well-hydrated by drinking plenty of water can help manage mild dehydration-related side effects.

Use in Driving and Operating Machinery

  • This medicine typically does not impair your ability to drive or operate machinery. However, individual responses can vary, so it is advised to be cautious until you know how the medication affects you.

Use in Pregnancy and Lactation

  • Bempedoic Acid + Ezetimibe is contraindicated during pregnancy. If pregnancy occurs while taking this medication, discontinue its use immediately and consult your doctor.
  • It is recommended to avoid breastfeeding while taking this medication due to the potential passage into breast milk.

Caution in Other Conditions

  • Caution should be taken when using Bempedoic Acid + Ezetimibe in patients with mild hepatic impairment. Regular monitoring of liver enzyme levels may be advisable.
  • Patients with a history of gout should exercise caution as Bempedoic acid could potentially increase uric acid levels.

Special Dietary and Lifestyle Recommendations

  • Maintain a low-cholesterol and low-fat diet to enhance the effectiveness of Bempedoic Acid + Ezetimibe in lowering LDL cholesterol.
  • Regular physical activity such as walking, cycling, or swimming can help improve cardiovascular health.
  • Avoid foods high in saturated fats and trans fats, such as fatty meats, full-fat dairy products, and processed snacks, which can increase cholesterol levels.
  • Incorporate fibre-rich foods such as oats, legumes, fruits, and vegetables into your diet which can help absorb and eliminate cholesterol from the body.
  • Smoking cessation is highly recommended as smoking can exacerbate heart disease and counteract the benefits of cholesterol-lowering medications.

Frequently asked questions

No, Bempedoic Acid + Ezetimibe is not a steroid. It is a combination medication used to lower levels of LDL ("bad") cholesterol in the blood.

There is no known effect of Bempedoic Acid + Ezetimibe on sleep. However, if you experience any unusual symptoms, you should consult your doctor.

Before taking Bempedoic Acid + Ezetimibe, it is advisable to consult your doctor about your concerns about fertility. 

There are no specific diet restrictions mentioned in the information for this medicine. However, it is prescribed along with diet and exercise for lowering cholesterol levels in the blood.

While it is generally safe to take daily, Bempedoic Acid + Ezetimibe should only be taken as per the directions provided by your doctor. 

The time taken for Bempedoic Acid + Ezetimibe to show its effects can vary among individuals and depends on various factors. You should discuss this with your doctor.

Bempedoic Acid + Ezetimibe is taken as per your doctor's instructions.

Terms & Conditions


Available medicines for BEMPEDOIC ACID + EZETIMIBE
Bemzire Ez Tablet 10
Bemzire Ez Tablet 10
La Renon
Pack of 10 Units
₹262.40
MRP ₹320.00
18.00% OFF
Bempesta Ez Tablet 10
Bempesta Ez Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹229.60
MRP ₹280.00
18.00% OFF
Bemezy Tablet 10
Bemezy Tablet 10
Usv Pvt Ltd
Pack of 10 Units
₹262.40
MRP ₹320.00
18.00% OFF
Bempidoc Ez Tablet 10
Bempidoc Ez Tablet 10
Steris Healthcare
Pack of 10 Units
₹159.68
MRP ₹320.00
50.10% OFF
Bemdac Ez Tablet 10
Bemdac Ez Tablet 10
Zydus Healthcare Ltd
Pack of 10 Units
₹269.66
MRP ₹328.85
18.00% OFF
Brillo Ez Tablet 10
Brillo Ez Tablet 10
Sun Pharmaceutical Industries Ltd
Pack of 10 Units
₹243.54
MRP ₹297.00
18.00% OFF
Bemneo Ez 180/10 MG Tablet 10
Bemneo Ez 180/10 MG Tablet 10
Abbott India Ltd.
Pack of 10 Units
₹319.80
MRP ₹390.00
18.00% OFF
Bempetol Ez Tablet 10
Bempetol Ez Tablet 10
Signature Phytochemical Industries
Pack of 10 Units
₹203.78
MRP ₹299.00
31.85% OFF

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