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Benzalkonium Chloride + Nepafenac

Uses of Benzalkonium Chloride + Nepafenac

  • The primary use of Benzalkonium Chloride + Nepafenac is for the management of pain and inflammation associated with cataract surgery. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs) and antimicrobial preservatives.

Side effects of Benzalkonium Chloride + Nepafenac

  • Capsular opacity (a common complication that can occur after cataract surgery)

  • Decreased visual acuity

  • Foreign body sensation

  • Increased intraocular pressure

  • Sticky sensation

How Benzalkonium Chloride + Nepafenac works

  • Benzalkonium Chloride + Nepafenac is an ophthalmic solution with anti-inflammatory and antimicrobial properties.

  • Nepafenac, once applied to the eye, is converted into amfenac, its active form. Amfenac diminishes inflammation by blocking an enzyme called prostaglandin H synthase or cyclooxygenase, which is essential for prostaglandin production. Prostaglandins are substances that increase inflammation.

  • Benzalkonium Chloride acts as a preservative in the solution. Being a quaternary ammonium compound, it disrupts the bacterial membrane, thus preventing bacterial contamination. It also enhances the absorption of Nepafenac into the eye. Together, these two components help to manage discomfort and inflammation in the eye.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Benzalkonium Chloride + Nepafenac is available as an ophthalmic solution for application into the eye.

Age and Dose Restrictions

  • This medicine is primarily intended for adult use. The safety and efficacy of Benzalkonium Chloride + Nepafenac in children under 10 years have not been established.

Contraindications

  • Benzalkonium Chloride + Nepafenac is contraindicated in patients who have shown hypersensitivity to any of its ingredients or to other non-steroidal anti-inflammatory drugs (NSAIDs) (like naproxen and ibuprofen).

Other Medications to Avoid

  • This combination may interact with other topical ophthalmic products (like corticosteroid eye drops) and blood thinners (like warfarin). Using multiple eye medications at the same time could dilute the effects of Benzalkonium Chloride + Nepafenac.

  • If you are taking any prescription or over-the-counter medications, it's crucial to consult your doctor before using Benzalkonium Chloride + Nepafenac.

    Overdose and Missed Dose

  • Overdosing on Benzalkonium Chloride + Nepafenac is unlikely due to the small volume of the ophthalmic solution. However, if accidentally ingested, immediately seek medical attention.

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you forget to instill this medicine, administer it as soon as you remember. Do not double the dose to make up for a missed one.

Management of Side Effects

  • Most side effects are temporary, generally harmless, and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage dry eyes.

  • Try resting and closing your eyes if they feel tired or irritated.

Use in Driving and Operating Machinery

  • As Benzalkonium Chloride + Nepafenac may cause temporary blurred vision, you should avoid driving or operating heavy machinery until your vision is clear.

Use in Pregnancy and Lactation

  • Benzalkonium Chloride + Nepafenac should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. It is not known whether this medicine passes into breast milk. Therefore, it should be used with caution during breastfeeding. Please consult your doctor for advice.

Caution in Other Conditions

  • Patients with corneal disease or diabetes may have an increased risk of corneal effects when using Benzalkonium Chloride + Nepafenac and should thus exercise caution.

Special Dietary and Lifestyle Recommendations

  • Maintain a healthy lifestyle to promote overall eye health.

  • Regular eye check-ups can help monitor your condition and any potential side effects of the medication.

  • Avoid rubbing your eyes excessively, as this can lead to irritation.

  • Ensure a well-balanced diet rich in vitamins C and E, zinc, lutein, zeaxanthin and omega-3 fatty acids, which are beneficial for eye health.

  • Stay hydrated to maintain moisture on the eye surface.

  • Avoid exposure to direct sunlight or wind that may dry your eyes; wearing sunglasses can help protect against these environmental factors.

  • Rest your eyes regularly if your screen time is high or you perform activities that require intense focus.

Frequently asked questions

No, Benzalkonium Chloride + Nepafenac is not a steroid medication. Benzalkonium chloride acts as an antimicrobial preservative, while nepafenac is a non-steroidal anti-inflammatory drug (NSAID).

There has been no scientific evidence that suggests that Benzalkonium Chloride + Nepafenac affects sleep. However, individual responses may vary. It would be wise to consult your doctor if you notice any changes in your sleep pattern after using this medicine.

No specific studies have indicated that the use of Benzalkonium Chloride + Nepafenac has an impact on fertility. However, if you are planning to conceive or have had difficulty conceiving, it is advisable to discuss this with your doctor.

No specific dietary restrictions have been associated with the use of Benzalkonium Chloride + Nepafenac. However, if you are on a specific diet due to other health conditions, do inform your doctor about it.

Yes, it is safe to use Benzalkonium Chloride + Nepafenac daily as per the prescribed dosage from your doctor. It is important not to exceed or lower the dose without consulting your doctor.

The exact time may vary depending on individual responses and the specific condition being managed. It is best to follow your doctor's instructions on usage and observe any changes in your condition.

The best time to use Benzalkonium Chloride + Nepafenac is as directed by your doctor, usually before and after cataract surgery.

Terms & Conditions


Benzalkonium Chloride + Nepafenac in other salts

BENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEBENZALKONIUM CHLORIDE + ZINC OXIDEBENZALKONIUM CHLORIDE + BROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINBENZALKONIUM CHLORIDE + CYCLOPENTOLATEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONENEPAFENACBENZALKONIUM CHLORIDE + FLUOROMETHOLONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONE + TOBRAMYCINBENZALKONIUM CHLORIDE + GATIFLOXACINBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + TOBRAMYCINBENZALKONIUM CHLORIDE + CHOLINE SALICYLATEBENZALKONIUM CHLORIDE + DEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + BRIMONIDINE + TIMOLOLALCAFTADINE + BENZALKONIUM CHLORIDENEPAFENAC + OXYCHLORO COMPLEXBENZALKONIUM CHLORIDE + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + FLUCONAZOLEBENZALKONIUM CHLORIDE + KETOROLAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + LATANOPROSTBENZALKONIUM CHLORIDE + OLOPATADINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + BRIMONIDINEBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEBENZALKONIUM CHLORIDE + BEPOTASTINEBENZALKONIUM CHLORIDE + BRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + BIMATOPROSTBENZALKONIUM CHLORIDE + BIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + CYCLOSPORINBENZALKONIUM CHLORIDE + KETOROLAC + OLOPATADINEBENZALKONIUM CHLORIDE + DORZOLAMIDEBENZALKONIUM CHLORIDE + DORZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + LATANOPROST + TIMOLOLBENZALKONIUM CHLORIDE + LOTEPREDNOLBENZALKONIUM CHLORIDE + LOTEPREDNOL + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + MOXIFLOXACINBENZALKONIUM CHLORIDE + LOTEPREDNOL + MOXIFLOXACINBENZALKONIUM CHLORIDE + BROMFENACBENZALKONIUM CHLORIDE + MOXIFLOXACINBENZALKONIUM CHLORIDE + OLOPATADINEBENZALKONIUM CHLORIDE + PREDNISOLONEBENZALKONIUM CHLORIDE + TIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + TRAVOPROSTBENZALKONIUM CHLORIDE + NATAMYCINBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + NETARSUDILBENZALKONIUM CHLORIDE + GANCYCLOVIR
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