Benzalkonium Chloride + Ofloxacin
Uses of Benzalkonium Chloride + Ofloxacin
The primary use of Benzalkonium Chloride + Ofloxacin is in managing bacterial infections, specifically those affecting the eyes and ears. It belongs to the group of antimicrobial medicines.
Secondary uses include its application as a prophylaxis for ocular infections in pre- and post-operative settings, managing bacterial conjunctivitis, corneal ulcers and otitis externa.
Side effects of Benzalkonium Chloride + Ofloxacin
Local irritation in eyes or ear
Burning sensation in the applied area
Itching or redness at the application site
Eyelid swelling
Stinging sensation
How Benzalkonium Chloride + Ofloxacin works
Benzalkonium Chloride + Ofloxacin is an antimicrobial combination.
Benzalkonium Chloride is a quaternary ammonium compound antiseptic. It works by disrupting the cell walls of harmful bacteria. This leads to the leakage of the contents inside the bacteria and causes the bacteria to die. It manages a wide range of bacteria, as well as some fungi and viruses.
Ofloxacin is a fluoroquinolone antibiotic. It inhibits enzymes named DNA gyrase and topoisomerase IV in bacteria. These enzymes are necessary for the bacteria to replicate their DNA, repair it, and recombine it. By blocking these enzymes, ofloxacin stops the bacteria from growing and multiplying, leading to their death.
When combined, these two medicines work together to effectively manage a broad spectrum of bacterial infections.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
- Benzalkonium Chloride + Ofloxacin is available in the form of eye drops and ear drops for topical administration.
Age and Dose Restrictions
- This medicine is meant for both adults and children. However, for younger children, dose adjustments might be required based on the severity of the infection and other factors.
Contraindications
- This medicine is contraindicated in patients who are hypersensitive to any component of the formulation or quinolone antibiotics.
Other Medications to Avoid
- This combination may interact with other topical medications used in the eyes or ears (eg., corticosteroids like hydrocortisone, and other antibiotics like neomycin).
Overdose and Missed Dose
- Overdosing on Benzalkonium Chloride + Ofloxacin is unlikely as it is administered topically. Using the prescribed dosage is recommended to avoid any side effects.
- In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
- If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
- If experiencing dryness or redness, blinking several times can help spread the tears naturally and soothe the eye.
- To manage mild irritation or discomfort at the application site, ensure that you are applying the medicine correctly as per the instructions provided.
Use in Driving and Operating Machinery
- This medication may cause blurred vision or dizziness. Refrain from driving or handling heavy machinery until you are sure about how this medication affects you.
Use in Pregnancy and Lactation
- The safety of using Benzalkonium Chloride + Ofloxacin during pregnancy and lactation has not been fully established. It should only be used when clearly needed and prescribed by a doctor.
Caution in Other Conditions
- Patients with a history of ocular or ear diseases should exercise caution while using this combination.
- Benzalkonium Chloride + Ofloxacin can irritate the eyes and ears, particularly in case of prolonged usage. Therefore, individuals with sensitive eyes or ears must consult their doctor before starting this combination.
Special Dietary and Lifestyle Recommendations
- Protect your eyes from dust, direct sunlight, and other irritants which may lead to eye infections.
- Avoid using headphones or inserting any foreign objects in the ear as they may cause further damage and worsen the infection.
- Ensure adequate hydration to help maintain normal tear production, which is beneficial for those using ophthalmic preparations.
- Wearing sunglasses can help reduce discomfort caused by light sensitivity when using eye drop formulations that may cause this side effect.
Frequently asked questions
Is Benzalkonium Chloride + Ofloxacin a steroid?
No, it is not a steroid. Benzalkonium Chloride is a quaternary ammonium compound widely used as a preservative and antiseptic agent, and Ofloxacin is a synthetic fluoroquinolone antibiotic used to manage bacterial infections.
Can Benzalkonium Chloride + Ofloxacin cause drowsiness?
There is no mention of drowsiness as a side effect in the provided references. However, each person may react differently to medication and it is always best to consult your doctor if you experience any unusual symptoms.
Can I wear contact lenses while using Benzalkonium Chloride + Ofloxacin?
No, patients are advised not to wear contact lenses during treatment with this combination of medicine.
Can Benzalkonium Chloride + Ofloxacin affect my mood?
There is no direct link between this medicine's use and mood changes. If you notice any unusual mood changes while using this medicine, do consult your doctor.
Is Benzalkonium Chloride + Ofloxacin addictive?
No. There is no evidence suggesting that this medicine can lead to addiction or dependence.
Is Benzalkonium Chloride + Ofloxacin safe for long-term use?
The safety and effectiveness of long-term use have not been established, and it is typically used for a prescribed duration to manage specific conditions. Always follow your doctor's guidance on the duration of use.
How quickly does Benzalkonium Chloride + Ofloxacin start working?
The onset of action can vary depending on several factors, including the type and severity of the infection. Typically, you should start to see an improvement in your symptoms within a few days of use. Consult your doctor if your symptoms do not improve or worsen.
Benzalkonium Chloride + Ofloxacin in other salts
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