Home/Drugs By Ailments / Benzalkonium Chloride + Tobramycin

Benzalkonium Chloride + Tobramycin

Uses of Benzalkonium Chloride + Tobramycin

  • Benzalkonium Chloride + Tobramycin is primarily used for managing bacterial infections of the eye. It falls under the category of aminoglycoside antibiotics in combination with a preservative.

  • It can manage conditions such as conjunctivitis (pink eye) and corneal ulcers. The medication has been found effective against various gram-negative and gram-positive bacteria.

Side effects of Benzalkonium Chloride + Tobramycin

  • Temporary burning sensation

  • Stinging in the eyes

  • Irritation

  • Itching

  • Redness of the eyes

How Benzalkonium Chloride + Tobramycin works

  • Tobramycin, the antibiotic in this combination, works by attaching itself to a specific part of harmful bacteria, known as the 30S ribosomal subunit. This action stops the bacteria from making proteins, which they need to grow and multiply.

  • Benzalkonium Chloride is a preservative that has its own antibacterial activity. It breaks down the outer covering of bacterial cells, which makes it easier for Tobramycin to penetrate these cells and do its job more effectively.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Benzalkonium Chloride + Tobramycin is available in the form of eye drops, which is administered topically.

Age and Dose Restrictions

  • Benzalkonium chloride + Tobramycin eye drops are suitable for use in both adults and children.

Contraindications

  • Benzalkonium Chloride + Tobramycin is contraindicated in patients with a known hypersensitivity to tobramycin, benzalkonium chloride, or any other component of the eye drops. It is also contraindicated in individuals who have a known allergy to other aminoglycoside antibiotics.

Other Medications to Avoid

  • This combination may interact with other topical eye medications (such as other antibiotics or steroids), oral aminoglycosides (such as gentamicin and neomycin), and certain diuretics (such as furosemide).

Overdose and Missed Dose

  • Overdose with Benzalkonium Chloride + Tobramycin eye drops is unlikely to occur due to the administration route. However, excessive use should be avoided as it may lead to increased side effects.

  • If you forget to administer a dose of Benzalkonium Chloride + Tobramycin, apply it as soon as you remember. If it is nearly time for the next dose, skip the missed dose and resume your regular dosing schedule.

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.

  • Ensure that you are applying the eye drops correctly without touching the dropper tip to your eye or any other surface.

  • To manage mild stinging or burning sensations that might occur just after application, you can close your eyes gently for one to two minutes to help soothe them.

Use in Driving and Operating Machinery

  • Benzalkonium Chloride + Tobramycin may cause temporary blurring of vision after application. It is recommended that you avoid driving or operating heavy machinery until your vision has cleared.

Use in Pregnancy and Lactation

  • The safety of using Benzalkonium Chloride + Tobramycin during pregnancy and lactation has not been fully established. Consult your doctor for advice before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Caution should be exercised when using Benzalkonium Chloride + Tobramycin in patients with pre-existing eye conditions such as severe keratitis or severe epithelial disorders.

Special Dietary and Lifestyle Recommendations

  • Maintain good eye hygiene while being treated for an eye infection. This includes washing hands before applying eye drops and avoiding touching the eyes with unclean hands.

  • Protect your eyes from dust, smoke, strong winds, and bright light during treatment to prevent irritation and aid recovery.

  • If wearing contact lenses, follow the doctor's instructions carefully regarding removal before applying eye drops; benzalkonium chloride can affect certain types of contact lenses.

Frequently asked questions

No, Benzalkonium Chloride + Tobramycin is not a steroid. It is a combination of an antibiotic (tobramycin) and a preservative (benzalkonium chloride).

There is no data suggesting that Benzalkonium Chloride + Tobramycin eye drops have any impact on sleep. However, different individuals may have varied responses to any medication.

There is no specific information available suggesting that Benzalkonium Chloride + Tobramycin has any impact on fertility. As always, if you have concerns about your fertility, it is advisable to consult with your doctor.

There are no specific dietary restrictions when using Benzalkonium Chloride + Tobramycin eye drops. However, maintaining a healthy diet is always beneficial for overall health.

The best time to use this medication will be as per your doctor's direction. There is no specific time that is universally considered the best for everyone.

Improvements from using Benzalkonium Chloride + Tobramycin eye drops can typically be noticed within 1-2 days of starting treatment. However, it's important to continue the full course of treatment as advised by your doctor.

Benzalkonium Chloride + Tobramycin eye drops are prescription medicine and are not typically available over the counter. Always consult your doctor before using any medication.

Terms & Conditions


Benzalkonium Chloride + Tobramycin in other salts

BENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEBENZALKONIUM CHLORIDE + ZINC OXIDEBENZALKONIUM CHLORIDE + BROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINBENZALKONIUM CHLORIDE + CYCLOPENTOLATEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONE + TOBRAMYCINFLUOROMETHOLONE + TOBRAMYCINBENZALKONIUM CHLORIDE + GATIFLOXACINDEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + NEPAFENACTOBRAMYCINBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONEMOXIFLOXACIN + TOBRAMYCINBENZALKONIUM CHLORIDE + CHOLINE SALICYLATEBENZALKONIUM CHLORIDE + DEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + BRIMONIDINE + TIMOLOLALCAFTADINE + BENZALKONIUM CHLORIDEBENZALKONIUM CHLORIDE + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + FLUCONAZOLEBENZALKONIUM CHLORIDE + KETOROLAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + LATANOPROSTBENZALKONIUM CHLORIDE + OLOPATADINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + BRIMONIDINEBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEBENZALKONIUM CHLORIDE + BEPOTASTINEBENZALKONIUM CHLORIDE + BRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + BIMATOPROSTBENZALKONIUM CHLORIDE + BIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + CYCLOSPORINBENZALKONIUM CHLORIDE + KETOROLAC + OLOPATADINEBENZALKONIUM CHLORIDE + DORZOLAMIDEBENZALKONIUM CHLORIDE + DORZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + LATANOPROST + TIMOLOLBENZALKONIUM CHLORIDE + LOTEPREDNOLBENZALKONIUM CHLORIDE + LOTEPREDNOL + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + MOXIFLOXACINBENZALKONIUM CHLORIDE + LOTEPREDNOL + MOXIFLOXACINBENZALKONIUM CHLORIDE + BROMFENACBENZALKONIUM CHLORIDE + MOXIFLOXACINBENZALKONIUM CHLORIDE + OLOPATADINEBENZALKONIUM CHLORIDE + PREDNISOLONEBENZALKONIUM CHLORIDE + TIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + TRAVOPROSTBENZALKONIUM CHLORIDE + NATAMYCINBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + NETARSUDILBENZALKONIUM CHLORIDE + GANCYCLOVIR
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