Blonanserin
Uses of Blonanserin
Blonanserin is primarily used for the management of schizophrenia and other psychotic disorders. It belongs to the class of atypical antipsychotic medications.
Additionally, there's some evidence suggesting its efficacy in managing conditions such as delusional disorder, treatment-resistant schizophrenia, and bipolar mania. However, these are not the official uses of the medication.
Side effects of Blonanserin
Insomnia
Sedation
Weight gain
Anxiety
Constipation
How Blonanserin works
Blonanserin is an atypical antipsychotic medication.
It primarily works by blocking serotonin 5-HT2A and dopamine D2 receptors in the brain. These chemicals, serotonin and dopamine, influence mood, behaviour, and thought processes. By blocking these receptors, Blonanserin helps manage schizophrenia symptoms like hallucinations and delusions. It also tends to cause fewer movement disorders (extrapyramidal side effects) compared to older, "typical" antipsychotics, which mostly target only dopamine D2 receptors. This dual receptor blockade is thought to improve symptoms more effectively and with fewer movement-related side effects.
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Expert Advice
Dosage Forms Available
Blonanserin is available in the form of tablets for oral administration.
Age and Dose Restrictions
Blonanserin is generally prescribed for adults, and its suitability and dosage for those under 18 should be determined by a doctor.
Contraindications
Blonanserin should not be used by patients with a known hypersensitivity to the medicine or any of its excipients.
Other Medications to Avoid
Blonanserin may interact with strong inhibitors of CYP3A4 (e.g., itraconazole, clarithromycin) and strong inducers of CYP3A4 (e.g., rifampicin, carbamazepine) and sedating medications (e.g., benzodiazepines).
Overdose and Missed Dose
Overdosing on Blonanserin could lead to sedation, hypotension, extrapyramidal reactions, and QT prolongation. If such symptoms occur, medical attention should be sought immediately.
If a dose of Blonanserin is missed, it should be taken as soon as remembered. However, if it is close to the time for the next dose, the missed dose should be skipped.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage side effects such as constipation, it may help to drink plenty of fluids and consume dietary fibre.
If experiencing insomnia or sedation, adjusting the timing of the dose could potentially help mitigate these effects.
Use in Driving and Operating Machinery
Blonanserin may impair your ability to drive or operate heavy machinery due to potential side effects such as dizziness and sedation. It is advised to refrain from such activities if these effects are experienced.
Use in Pregnancy and Lactation
Blonanserin is not recommended during pregnancy and lactation unless prescribed by the doctor. It is advised to consult a doctor before using this medicine during pregnancy and lactation.
Caution in Other Conditions
Extra caution should be taken when using Blonanserin in elderly patients or those with liver or kidney impairments, as dose adjustments may be necessary.
Patients with a history of seizures, cardiovascular disease, diabetes, or angle-closure glaucoma should also use this medicine with caution.
Special Dietary and Lifestyle Recommendations
Limit intake of caffeinated beverages as these may exacerbate side effects such as anxiety and insomnia.
Frequently asked questions
Will the use of Blonanserin affect my weight?
Blonanserin may cause weight gain as a side effect in some individuals but it varies from person to person. If you are concerned about potential weight changes, you should discuss it with your doctor.
Is Blonanserin a steroid?
Blonanserin is not a steroid but an atypical antipsychotic medication.
Does Blonanserin have any effect on sleep?
Yes, Blonanserin can affect sleep, potentially causing insomnia or sedation that may alter your sleep pattern. Consult your doctor if you observe any sleep issues.
Will Blonanserin affect fertility?
Blonanserin is not known to affect fertility. However, if you have concerns about fertility and the use of this medication, it's advisable to consult your doctor.
Is it safe to take Blonanserin daily?
Blonanserin should be taken exactly as prescribed by your doctor, following their instructions for dosage and duration.
How much time does Blonanserin take to work?
After oral administration, Blonanserin reaches peak blood concentrations in about 2 hours. However, the exact duration may vary among individuals depending on various factors.
What is the best time to take Blonanserin?
Blonanserin can be taken orally with or without food as per your doctor's instructions. The exact timing should be determined, considering your overall medication schedule and lifestyle.
List of Medicines for Blonanserin
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