Bosentan
Uses of Bosentan
The primary use of Bosentan is to manage pulmonary arterial hypertension. It belongs to the class of medications known as endothelin receptor antagonists.
Secondary uses of Bosentan include the management of chronic thromboembolic pulmonary hypertension in patients who are not surgical candidates or have residual/recurrent pulmonary hypertension after a type of surgery called pulmonary endarterectomy.
Side effects of Bosentan
Headache
common cold
Abnormal liver function tests
Flushing
How Bosentan works
Bosentan is a dual endothelin receptor antagonist.
It works by preventing the binding of endothelin, a naturally occurring substance, to its receptors found on blood vessels' surfaces. Endothelin causes narrowing of blood vessels and increases blood pressure, especially in the lungs.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Bosentan can be taken orally (film-coated tablet and dispersible tablet).
Age and Dose Restrictions
This medicine is primarily intended for use in adults aged 18 and older.
Contraindications
Bosentan is contraindicated in patients with known hypersensitivity to the active substance or any of its components. It is also contraindicated in patients with severe hepatic impairment or elevated baseline liver aminotransferases.
Other Medications to Avoid
Bosentan may interact with antifungals (ketoconazole) and antibiotics (rifampin).
Overdose and Missed Dose
Overdose of Bosentan can have serious consequences. Seek immediate medical attention if you take more than your prescribed dose.
If you miss a dose, take it as soon as you remember. But if it is nearly time for the next dose, skip the missed dose and return to your regular schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Increase fluid intake if you experience headache or flushing.
Maintain hydration and rest if you experience dizziness.
Use in Driving and Operating Machinery
Bosentan may cause side effects like dizziness or fatigue, which could potentially affect your ability to drive or operate machinery.
Use in Pregnancy and Lactation
Bosentan is not recommended during pregnancy due to potential harm to the foetus. The use of Bosentan during lactation is not advised.
Caution in Other Conditions
Patients with mild to moderate hepatic impairment should exercise caution when taking Bosentan.
Renal impairment does not require dose adjustment for Bosentan, but patients with severe impairment should exercise caution.
Special Dietary and Lifestyle Recommendations
Regular monitoring of blood pressure can help track the effectiveness of the medication.
Too much salt can increase blood pressure, so limit your intake to less than 5 g daily. Avoid adding extra salt to your food.
Avoid processed foods high in sodium.
Frequently asked questions
Is Bosentan a steroid?
No, Bosentan is not a steroid. It belongs to a class of medicines known as endothelin receptor antagonists.
Does the Bosentan have any effect on sleep?
Bosentan is not typically associated with affecting sleep disturbances, but individual reactions may vary. Consult your doctor if you experience any unusual sleep patterns while taking Bosentan.
Will Bosentan affect fertility?
Yes, one of the potential side effects of Bosentan is decreased sperm counts in men. If you are planning to conceive, consult with your doctor before starting this medication.
Is it safe to take Bosentan daily?
The safety of taking Bosentan daily depends on your individual health condition and the dosage prescribed by your doctor. Do not alter your dose or stop taking the medicine without consulting your doctor.
How much time does Bosentan take to work?
The time taken for Bosentan to show its effect may vary depending on the severity and type of condition being managed. It is best to discuss this with your doctor.
What is the best time to take Bosentan?
Bosentan should be taken at the same time each day to maintain a constant level in the body, as advised by your doctor.
Is Bosentan available over the counter, or do I need a prescription?
Bosentan is a prescription medicine and is not available over the counter.
Subscribe
Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.
Download Truemeds
Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.
Contact Us
Our customer representative team is available 7 days a week from 9 am - 9 pm.
v3.4.16
2024 - Truemeds | All rights reservedOur Payment Partners
