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Caffeine + Cetirizine + Nimesulide + Phenylephrine

Uses of Caffeine + Cetirizine + Nimesulide + Phenylephrine

  • The main use of Caffeine + Cetirizine + Nimesulide + Phenylephrine is to manage symptoms associated with the common cold, flu, and allergies. It belongs to a group of medicines known as analgesics, antihistamines, decongestants, and stimulants.

  • This combination medicine is also utilised for its anti-inflammatory properties in reducing fever and body aches related to these conditions. Furthermore, it helps relieve sinus pressure and nasal congestion.

Side effects of Caffeine + Cetirizine + Nimesulide + Phenylephrine

  • Dizziness

  • Nausea

  • Dry mouth

  • Trouble sleeping

  • Fatigue

How Caffeine + Cetirizine + Nimesulide + Phenylephrine works

  • Caffeine + Cetirizine + Nimesulide + Phenylephrine is a combination medicine that provide symptomatic relief from common cold, flu and various allergic reactions.

  • Caffeine acts as a central nervous system stimulant. It helps combat drowsiness and fatigue by blocking the action of adenosine, a neurotransmitter that promotes sleep and relaxation.

  • Cetirizine is an antihistamine. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms like itching, sneezing, runny nose, and watery eyes.

  • Nimesulide is a nonsteroidal anti-inflammatory medication (NSAID). It reduces inflammation and pain by blocking the production of certain chemicals in the body called prostaglandins that contribute to fever, pain and swelling.

  • Phenylephrine is a decongestant. It works by narrowing the blood vessels in the nasal passages, thereby reducing nasal congestion and making it easier to breathe.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage forms available

  • Caffeine + Cetirizine + Nimesulide + Phenylephrine is available in tablet form.

  • The medicine is taken orally and can be consumed with or without food.

Age and dose restrictions

  • This combination medicine is meant for adults and children aged 12 years and older.

Contraindications

  • Caffeine + Cetirizine + Nimesulide + Phenylephrine is contraindicated in patients with known allergies to any of its components.

  • It is also contraindicated in individuals who have taken MAO inhibitors within the past 14 days.

  • This medication should not be used by children under 12 years of age.

Other medications to avoid

  • This combination can interact with opioid pain or cough relievers (such as codeine and hydrocodone), medicines for sleep or anxiety (like alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), and other antihistamines (like diphenhydramine, chlorpheniramine).

Overdose and missed dose

  • An overdose of Caffeine + Cetirizine + Nimesulide + Phenylephrine may lead to severe symptoms such as rapid heartbeat, severe dizziness, trouble breathing, or fainting. If these occur, seek immediate medical attention.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten tablet.

Management of side effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage a dry mouth, sip water regularly.

  • If experiencing drowsiness, try taking the medicine at a time when you can rest until you know how it affects you.

Use in driving and operating machinery

  • This medication can cause drowsiness or dizziness. You should avoid driving or operating heavy machinery until you know how it affects you.

Use in pregnancy and lactation

  • It is advised to consult a doctor before using Caffeine + Cetirizine + Nimesulide + Phenylephrine during pregnancy or while breastfeeding. The safety of this medication for use in these conditions has not been established.

Caution in other conditions

  • Individuals with high blood pressure, heart disease, thyroid disorders, diabetes, enlarged prostate, liver or kidney disease, a history of stomach ulcers or bleeding, or glaucoma should use this medication with caution.

Special dietary and lifestyle recommendations

For individuals dealing with symptoms of colds or allergies managed by Caffeine + Cetirizine + Nimesulide + Phenylephrine:

  • Maintain hydration by drinking adequate fluids; this can help thin mucus.

  • Consume a balanced diet rich in vitamins and minerals to support the immune system.

  • Avoid smoking and exposure to second-hand smoke; these can exacerbate respiratory symptoms.

  • Ensure sufficient rest to help your body recover faster.

  • Consider using a humidifier in your room to ease breathing if experiencing nasal congestion.

Frequently asked questions

No, Caffeine + Cetirizine + Nimesulide + Phenylephrine is not a steroid. It is a combination medicine that contains a central nervous system stimulant, an antihistamine, an NSAID, and a decongestant.

Yes, this medicine contains caffeine which can cause trouble sleeping or insomnia in some people. Additionally, cetirizine can cause mild drowsiness.

There is no scientific data to suggest that this combination of medicines affects fertility. However, if you are trying to conceive or are concerned about fertility, it is advisable to consult your doctor.

There are no specific diet restrictions while taking this medicine. However, it should be noted that caffeine can increase the effects of certain foods and beverages such as those high in sugar and fat.

This combination medicine is intended for temporary use and should not be taken daily over extended periods without the advice of a doctor.

The time required for this medicine to show its effect can vary depending on the individual and the severity of their symptoms. It is advisable to follow the instructions given by your doctor.

This medicine can be taken at any time of the day, with or without food. However, due to the presence of caffeine, it may interfere with sleep if taken late in the day.

Terms & Conditions


Caffeine + Cetirizine + Nimesulide + Phenylephrine in other salts

CETIRIZINENIMESULIDE + PARACETAMOL/ACETAMINOPHENLEVOCETIRIZINELEVOCETIRIZINE + MONTELUKASTNIMESULIDECETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINEPARACETAMOL + CAFFEINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + LEVOCETIRIZINELEVOCETIRIZINE + PSEUDOEPHEDRINENIMESULIDE + TIZANIDINECHLORPHENIRAMINE + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINEDICLOFENAC + NIMESULIDECPM + DEXTROMETHORPHAN + PHENYLEPHRINENIMESULIDE + SERRATIOPEPTIDASENIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEAMBROXOL + LEVOCETIRIZINE + MONTELUKASTCETIRIZINE + PSEUDOEPHEDRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECAFFEINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDEDICYCLOMINE + NIMESULIDEPHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECARBOXY METHYL CELLULOSE + NAPHAZOLINE + PHENYLEPHRINENAPHAZOLINE + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORBUTOL + PHENYLEPHRINE + TROPICAMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESINBROMHEXINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + PHENYLEPHRINE + SALBUTAMOLAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + MENTHOLBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHENAMBROXOL + CETIRIZINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESIN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + DEXTROMETHORPHANDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + MENTHOL + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHANCETIRIZINE + DEXTROMETHORPHAN + PSEUDOEPHEDRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINEBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DIETHYLCARBAMAZINECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PHENYLEPHRINEACEBROPHYLLINE + LEVOCETIRIZINE + MONTELUKASTCAFFEINE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PSEUDOEPHEDRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEASPIRIN + CAFFEINECAMYLOFIN + NIMESULIDECETIRIZINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENAZONEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDEXTROPROPOXYPHENE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDE + PARACETAMOL/ACETAMINOPHENAMBROXOL + LEVOCETIRIZINE + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + ERGOTAMINE + PARACETAMOL/ACETAMINOPHEN + PROCHLORPERAZINELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN
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