Calcium Folinate

Dosage Forms Available

• Calcium Folinate is available in two main formulations.

• It can be administered as an injectable solution via intramuscular (IM) or intravenous (IV) routes.

• It is also available as tablets for oral administration.

Age and Dose Restrictions

• Calcium Folinate is suitable for use in both adults and children, with the specific age and dosage restrictions to be determined by the treating doctor based on the individual patient's medical condition and response to treatment.

Contraindications

• Calcium Folinate is contraindicated in patients who have a known hypersensitivity to folinate or folic acid derivatives.

• It should not be used in treating pernicious anaemia or other megaloblastic anaemias that are caused by a vitamin B12 deficiency.

Other Medications to Avoid

• Calcium Folinate may interact with certain medications such as antiepileptic drugs (phenobarbital, phenytoin, primidone), antibiotics (sulfamethoxazole-trimethoprim), and chemotherapy agents (like 5-fluorouracil).

Overdose and Missed Dose

• An overdose of Calcium Folinate could lead to severe side effects such as allergic reactions or gastrointestinal disturbances. In such situations, it is crucial to consult your doctor immediately.

• If you miss a dose of Calcium Folinate, take it as soon as you remember. However, If it is close to the time for your next dose, skip the missed dose and return to your normal dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For nausea and vomiting, try taking the medicine with or after a meal.

• If you experience fatigue or weakness, ensure you are getting enough rest and staying properly hydrated.

Use in Driving and Operating Machinery

• Calcium Folinate may cause side effects like dizziness or fatigue that could affect your ability to drive or operate heavy machinery. It is advised to avoid such activities if you experience these side effects.

Use in Pregnancy and Lactation

• Pregnant or breastfeeding women should consult their doctor before using Calcium Folinate. Its use should be carefully considered based on the benefits and potential risks.

Caution in Other Conditions

• Patients with a history of allergic reactions to folate or folinic acid should exercise caution while using Calcium Folinate.

• Those with pernicious anaemia, vitamin B12 deficiency, or renal impairment may also require dose adjustment or close monitoring when taking this medicine.

Special Dietary and Lifestyle Recommendations

• A balanced diet rich in folic acid can help manage underlying conditions that Calcium Folinate is used to treat. Foods like leafy green vegetables, fruits, beans, cereals, and breads are excellent sources of folic acid.

• Regular check-ups and blood tests are recommended to monitor the effectiveness of the treatment and any potential side effects.

• Avoiding alcohol and tobacco can also contribute towards overall health improvement.