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Carbimazole

Uses of Carbimazole

  • The primary use of Carbimazole is in managing hyperthyroidism and it belongs to the class of antithyroid medicines.

  • Additionally, Carbimazole is indicated for restoring normal thyroid function before partial surgical removal of the thyroid gland.

Side effects of Carbimazole

  • Nausea and vomiting

  • Mild headache

  • Joint pain

  • Skin rash or itching

  • Loss of taste

How Carbimazole works

  • Carbimazole is an antithyroid medicine.

  • It works by inhibiting the activity of an enzyme called thyroperoxidase in the thyroid gland. This enzyme is crucial for the synthesis of thyroid hormones called thyroxine (T4) and triiodothyronine (T3). By blocking this enzyme, Carbimazole prevents the conversion of iodide ions into iodine and their subsequent incorporation into tyrosyl residues. This process is essential for the formation of T4 and T3 hormones. As a result, the production of these thyroid hormones is reduced, leading to decreased levels in the bloodstream.

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Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Carbimazole can be taken orally (tablet or solution).

Age and Dose Restrictions

  • This medication is primarily meant for adults.

Contraindications

  • Carbimazole is contraindicated in individuals with a known hypersensitivity to the medicine or any component of the formulation.

  • It is not recommended for patients with a history of acute pancreatitis after Carbimazole administration or for patients with severe liver impairment. Severe blood dyscrasias are also conditions where Carbimazole should not be used.

Other Medications to Avoid

  • This medicine may interact with anticoagulants (like warfarin), beta-blockers (such as propranolol), cardiac glycoside (like digoxin), and methylxanthines (like theophylline).

Overdose and Missed Dose

  • If an overdose of Carbimazole occurs, medical attention should be sought immediately. Immediate symptoms may include skin rash, itching, nausea, vomiting, joint pain, and other signs of hypersensitivity.

  • If you miss a dose of Carbimazole, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose. Do not take a double dose to compensate for the forgotten one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help to alleviate the gastrointestinal disturbances that are common side effects of Carbimazole.

  • To manage skin rash and itching, avoid exposure to too much heat or sunlight.

Use in Driving and Operating Machinery

  • Carbimazole does not generally affect your ability to drive or operate machinery. However, if you do feel dizzy or uncoordinated after taking the medication, you should avoid these activities until you feel better.

Use in Pregnancy and Lactation

  • Carbimazole can cause harm to the foetus and should be used during pregnancy only if clearly needed. It is secreted in breast milk, so breastfeeding should be avoided while taking this medication. Always consult your doctor before use.

Caution in Other Conditions

  • Patients with liver or kidney disease or blood cell disorders should exercise caution when taking Carbimazole. Regular blood tests are required before and during therapy to monitor white blood cell counts and liver function.

Special Dietary and Lifestyle Recommendations

  • Foods rich in iodine like seaweed should be avoided as they can interfere with the effectiveness of the medication.

Frequently asked questions

No, Carbimazole is not a steroid. It is an antithyroid medication that helps manage hyperthyroidism.

Carbimazole does not typically affect sleep patterns. However, since one of the symptoms of hyperthyroidism is disturbed sleep, once the levels of thyroid hormone reduce, you may notice an improvement in your sleep.

Carbimazole does not directly affect fertility. Nevertheless, abnormal thyroid hormone levels can interfere with ovulation in women and sperm production in men, potentially affecting fertility. Once these levels are controlled with Carbimazole, fertility often improves.

Carbimazole has not been reported to cause any changes in the menstrual cycle directly. However, each individual may react differently to medicines, and it is always advisable to consult your doctor if you notice any unusual changes while taking this medication.

Yes, Carbimazole is usually taken daily to manage hyperthyroidism. However, it should be taken exactly as directed by your doctor.

Carbimazole generally starts reducing thyroid hormone levels within 2-4 weeks. However, it may take 4-8 weeks for you to experience full effects and symptom relief.

Yes, Carbimazole is a prescription medication and it is not available over-the-counter.

Terms & Conditions

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