Cariprazine

Dosage Forms Available

• Cariprazine is available in an oral formulation as capsules.

Age and Dose Restrictions

• Cariprazine is used primarily in the treatment of adults.

Contraindications

• Cariprazine should not be used by individuals who have a known allergy to cariprazine or any of its components.

• It is also contraindicated in elderly patients with dementia-related psychosis due to an increased risk of mortality.

Other Medications to Avoid

• Cariprazine can interact with medications affecting dopamine levels, such as other antipsychotics (e.g., risperidone, olanzapine), and those affecting liver enzymes (e.g., ketoconazole, rifampin). It may also interact with central nervous system depressants (e.g., benzodiazepines, opioids).

Overdose and Missed Dose

• Overdose of Cariprazine may potentially lead to severe adverse effects. If suspected of an overdose, seek immediate medical attention.

• In case a dose is missed, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can often help manage some side effects like dry mouth.

• Taking Cariprazine with meals may help manage gastrointestinal side effects such as nausea.

Use in Driving and Operating Machinery

• Cariprazine may cause dizziness, somnolence or sedation, affecting an individual's ability to drive or operate heavy machinery. It is advisable to avoid such activities if these effects are experienced.

Use in Pregnancy and Lactation

• It is advised for women who are pregnant or breastfeeding to consult their doctor before using Cariprazine. This is due to the potential risks it may pose to the developing fetus or nursing infant.

Caution in Other Conditions

• Patients with severe hepatic impairment or severe renal impairment should exercise caution while taking Cariprazine. Consultation with a doctor is necessary to assess the benefits and risks of this medication in these specific conditions.

Special Dietary and Lifestyle Recommendations

• A balanced diet, rich in fruits, vegetables, and whole grains can help promote overall health and well-being.

• Regular physical activity is beneficial for maintaining good mental health. However, individuals should consult their doctor before starting a new exercise regimen.

• Adequate sleep is essential for the proper functioning of the brain and can help manage symptoms of mental disorders like schizophrenia and bipolar disorder.

• It is advisable to limit caffeine intake as it can exacerbate certain symptoms associated with mental disorders.

• Smoking cessation and limitation of alcohol intake can contribute towards overall health improvement.