Home/Drugs By Ailments / Cefalexin + Probenecid

Cefalexin + Probenecid

Uses of Cefalexin + Probenecid

  • Cephalexin + Probenecid is primarily used in the management of susceptible bacterial infections and belongs to the group of cephalosporin antibiotics and uricosuric agents.
  • This combination is indicated for various types of infections including respiratory tract infections (bronchitis, pneumonia, tonsillitis, pharyngitis), skin and soft tissue infections, bone and joint infections, urinary tract infections (cystitis and prostatitis), and dental infections.

Side effects of Cefalexin + Probenecid

  • Diarrhoea
  • Nausea
  • Vomiting
  • Rash
  • Headache

How Cefalexin + Probenecid works

  • Cefalexin is a first-generation cephalosporin antibiotic. It works by inhibiting the synthesis of the bacterial cell wall. This is achieved by binding to and inactivating certain proteins (penicillin-binding proteins) crucial for building the bacterial cell wall. When these proteins fail, the cell wall formation gets disrupted, resulting in the death of the bacteria.
  • Probenecid is a uricosuric agent that plays a supporting role in this combination. It inhibits the function of certain channels in the kidneys responsible for excreting cefalexin from the body. This allows more cefalexin to remain in the body for longer, thereby increasing its effectiveness without needing to increase its dosage.
  • Together, Cephalexin + Probenecid provide a potent defence against susceptible bacterial infections.

Certified content

Written By

docImg
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage forms available

  • Cephalexin + Probenecid is available as oral tablets to be taken by mouth.

Age and dose restrictions

  • This medication is intended for use in adults and children of age above 12 years based on body weight and clinical assessment.

Contraindications

  • Individuals with known hypersensitivity to cephalosporin antibiotics, penicillins or probenecid should not take Cephalexin + Probenecid.
  • It is also contraindicated in patients diagnosed with carcinoid syndrome.

Other medications to avoid

  • Cephalexin + Probenecid may interact with NSAIDs (like ibuprofen and naproxen), aminoglycosides (like gentamicin and amikacin), tetracyclines (such as doxycycline and minocycline), macrolides (like erythromycin and azithromycin).

Overdose and missed dose

  • Overdose of Cephalexin + Probenecid may result in symptoms like nausea, vomiting, epigastric distress and diarrhoea. Immediate medical attention should be sought in such cases.
  • If a dose is missed, it should be taken as soon as possible. However, if it is already time for the next dose, the missed dose should be skipped to prevent potential overdose.

Management of side effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can reduce potential gastrointestinal side effects like diarrhoea or nausea.
  • Ensuring ample rest may help manage fatigue or dizziness.

Use in driving and operating machinery

  • As some people may experience dizziness or fatigue, caution is advised when driving or operating heavy machinery after taking Cephalexin + Probenecid.

Use in pregnancy and lactation

  • It is recommended to consult a doctor before using this medication during these periods.

Caution in other conditions

  • Patients with kidney impairment should exercise caution and may require dose adjustments when taking Cephalexin + Probenecid.
  • Persistent diarrhoea may be a sign of Clostridium difficile-associated diarrhoea, and the medicine should be discontinued and a doctor consulted.

Special dietary and lifestyle recommendations

  • Maintaining good personal hygiene can help prevent further bacterial infections.
  • Regular hand washing can help reduce the risk of spreading infection to others.
  • It's recommended to avoid close contact with others who have bacterial infections, if possible.
  • A balanced diet rich in vitamins and minerals can support the immune system in fighting off infections.

Frequently asked questions

No, Cephalexin + Probenecid is not a steroid. It is a combination of two active ingredients Cefalexin, a first-generation cephalosporin antibiotic, and Probenecid, a uricosuric agent.

Cephalexin + Probenecid is not associated with affecting sleep. However, if you have any concerns about this, you should discuss them with your doctor.

Cephalexin + Probenecid is not directly associated with affecting fertility. However, if you are planning to conceive, you should discuss this with your doctor.

The safety of daily consumption of Cephalexin + Probenecid depends on the duration and dosage prescribed by your doctor. The medicine is taken as advised by your doctor based on the type and severity of the infection.

Cefalexin, one of the components of the combination, reaches peak levels in the body 1-2 hours after an oral dose. The time it takes to start working can vary depending on the type of infection and individual patient factors.

Cephalexin + Probenecid can be taken with or without food. The best time to take this medicine would be as prescribed by your doctor, usually every 12 hours.

It is best to consult your doctor for alternatives to Cephalexin + Probenecid as different salts may work differently and their effect on your condition would depend on various factors like the severity and type of infection.

Terms & Conditions


Cefalexin + Probenecid in other salts

Available medicines for CEFALEXIN + PROBENECID
Unifex Forte 500/250 MG Tablet 6
Unifex Forte 500/250 MG Tablet 6
Bestochem Formulations (i) Ltd
Pack of 6 Units
₹62.06
MRP ₹75.68
18.00% OFF
Unifex Forte 500/250 MG Capsule 10
Unifex Forte 500/250 MG Capsule 10
Bestochem Formulations (i) Ltd
Pack of 10 Units
₹78.65
MRP ₹95.92
18.00% OFF
Ceff La 250/250 MG Tablet 10
Ceff La 250/250 MG Tablet 10
Lupin Ltd
Pack of 10 Units
₹75.44
MRP ₹92.00
18.00% OFF
Unifex 250/250 MG Tablet 10
Unifex 250/250 MG Tablet 10
Bestochem Formulations (i) Ltd
Pack of 10 Units
₹62.47
MRP ₹76.18
18.00% OFF
Unifex 500/500mg Capsule 10
Unifex 500/500mg Capsule 10
Bestochem Formulations (i) Ltd
Pack of 10 Units
₹62.47
MRP ₹76.18
18.00% OFF
Ceff-la 500/500 MG Tablet 10
Ceff-la 500/500 MG Tablet 10
Lupin Ltd
Pack of 10 Units
₹152.22
MRP ₹185.63
18.00% OFF
Alcephin La 500/500 MG Tablet 10
Alcephin La 500/500 MG Tablet 10
Alembic Pharmaceuticals Ltd
Pack of 10 Units
₹92.37
MRP ₹112.65
18.00% OFF
Cefalong Ds 500/500 MG Tablet 10
Cefalong Ds 500/500 MG Tablet 10
Dr. Reddys Laboratories Ltd
Pack of 10 Units
₹102.67
MRP ₹125.21
18.00% OFF

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.

playstoreIcon

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v3.5.0

copyright2024 - Truemeds | All rights reserved

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner