Cefepime
Uses of Cefepime
Cefepime is used for managing bacterial infections and belongs to the group of cephalosporin antibiotics.
Furthermore, it is indicated for moderate to severe pneumonia, febrile neutropenic patients (condition that occurs when a patient has a fever and a lower-than-normal number of neutrophils in their blood), urinary tract infections (UTIs), skin and skin structure infections, and complicated intra-abdominal infections in combination with metronidazole. It is also used for managing infections of the respiratory tract, genital tract, stomach, and biliary tract.
Side effects of Cefepime
Diarrhoea
Rash
Anaemia
Injection site pain, redness, swelling, or bleeding
Headache
How Cefepime works
Cefepime is a fourth-generation cephalosporin antibiotic.
It operates by interrupting the formation of the bacterial cell wall. Bacteria need a sturdy cell wall to survive and multiply. This medicine interferes with the synthesis of this wall, resulting in the death of bacteria that are susceptible to it. Consequently, this medicine helps in managing various types of bacterial infections, such as pneumonia, by disrupting their growth and spread, making the body's task of eliminating them more manageable.
Certified content
Written By
BDS, MDS
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
- Cefepime comes in an infusion solution and powder for injection into a muscle (intramuscular) or a vein (intravenous).
Age and Dose Restrictions
- Cefepime is intended for adults, children, and infants older than 2 months.
Contraindications
- This medicine is contraindicated in patients with known allergies to Cefepime. It should not be administered to patients who have experienced anaphylaxis with this medicine and gastrointestinal disease.
Other Medications to Avoid
- Cefepime can interact with cephalosporin antibiotics (e.g., cefaclor, cefadroxil) and anticoagulants (e.g., warfarin, heparin).
Overdose and Missed Dose
- If an overdose occurs, symptoms may include muscle spasms, seizures, confusion, and coma. It is essential to seek immediate medical attention.
- If a dose is missed, it should be administered as soon as possible. However, if it is near the time for the next dose, skip the missed dose and return to the regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless, resolving when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
- Take plenty of water to keep you hydrated to manage diarrhoea.
Use in Driving and Operating Machinery
- Cefepime does not generally affect the ability to drive or operate heavy machinery.
Use in Pregnancy and Lactation
- Cefepime should only be used in pregnancy if the benefits outweigh the risks. The medicine may pass into breast milk, so caution should be exercised when breastfeeding. Consult your doctor before using this medicine in pregnancy or lactation.
Caution in Other Conditions
- Caution is advised in patients with kidney disease or impairment and liver disease as dose adjustment may be necessary. People with a history of gastrointestinal diseases like colitis (inflammation or swelling of the large intestine or colon) should also exercise caution when using this medication.
Special Dietary and Lifestyle Recommendations
- Regular exercise may help strengthen the immune system, aiding in the fight against bacterial infections.
Frequently asked questions
Is Cefepime used for viral infections?
No, Cefepime is not used for viral infections. It is an antibiotic primarily used for bacterial infections.
Can Cefepime cause allergic reactions?
Yes, Cefepime can cause allergic reactions in some individuals who are sensitive to it or other cephalosporin antibiotics.
Will I experience mood changes while taking Cefepime?
While mood changes are not commonly associated with Cefepime, individuals may react differently to medications. If you notice any unusual changes in your mood or behaviour, consult your doctor immediately.
Does taking Cefepime require any specific medical monitoring or tests?
No specific monitoring is generally required during a course of Cefepime, but regular medical follow-up is recommended to check the progress of treatment.
Does Cefepime lead to addiction or dependency?
No, Cefepime does not lead to addiction or dependency as it is an antibiotic medicine, not a controlled substance.
Are there any alternative salts similar to Cefepime available in the market?
Yes, there are other cephalosporin antibiotics that may be used as alternatives to Cefepime. However, they should only be used under the guidance of a doctor.
Can I take other medicines while on a course of Cefepime?
Always inform your doctor about all the medicines you are currently taking before starting a new medicine like Cefepime, as certain drugs may interact with it.
Cefepime in other salts
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