Cefepime + Sulbactam

Dosage Forms Available

• Cefepime + Sulbactam is available as a sterile powder for reconstitution, specifically designed for injection.
• This medicine is administered either by intravenous infusion or deep intramuscular injection, which allows the medicine to enter the bloodstream directly and act quickly against infections.

Age and Dose Restrictions

• Cefepime + Sulbactam is meant for use in adult patients.

Contraindications

• Cefepime + Sulbactam is contraindicated in patients with known serious hypersensitivity to cefepime, sulbactam, or other beta-lactam antibiotics.
• It is also contraindicated in individuals who have had severe allergic reactions to penicillin antibiotics.

Other Medications to Avoid

• This combination may interact with aminoglycosides (such as gentamicin and amikacin), loop diuretics (including furosemide and bumetanide), live vaccines (like oral typhoid vaccine), and anticoagulants (such as warfarin).

Overdose and Missed Dose

• An overdose of Cefepime + Sulbactam may result in increased severity of side effects such as confusion, seizures, or severe diarrhoea. Immediate medical attention should be sought if an overdose is suspected.
• If you miss a dose of Cefepime + Sulbactam, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage nausea, try taking the medicine with food or water.
• If experiencing injection site discomfort, alternating the injection site may help reduce irritation.

Use in Driving and Operating Machinery

• Cefepime + Sulbactam can cause dizziness or drowsiness in some individuals. You should avoid driving or operating heavy machinery if you experience these side effects after receiving this medicine.

Use in Pregnancy and Lactation

• Cefepime + Sulbactam should only be used during pregnancy and lactation if clearly needed. Consult your doctor before receiving this medication.

Caution in Other Conditions

• Patients with renal impairment should exercise caution when using Cefepime + Sulbactam due to the need for dosage adjustment and potential accumulation of the medicine.
• Individuals with a history of gastrointestinal diseases linked to antibiotic use should also use this medication cautiously due to the risk of Clostridium difficile-associated diarrhoea.

Special Dietary and Lifestyle Recommendations

• Maintain adequate hydration while taking this medication to help prevent kidney issues that can arise from toxicity, especially when using other medicines like loop diuretics simultaneously.
• Incorporate a balanced fibre-rich diet to help manage potential gastrointestinal side effects such as nausea or abdominal pain.
• Practice good personal hygiene and proper wound care to support recovery from skin infections being treated by this medication.
• Rest adequately while undergoing treatment to support immune function and recovery from infection.