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Cefixime + Moxifloxacin
Uses of Cefixime + Moxifloxacin
Cefixime + Moxifloxacin is a potent antibiotic combination used primarily for treating various bacterial infections. It falls under the group of third-generation cephalosporin and fluoroquinolones.
Additionally, it can be used for managing conditions like middle ear infections, tonsillitis, bronchitis exacerbations, pneumonia, urinary tract infections, skin infections, typhoid fever, gonorrhoea and sinusitis.
Side effects of Cefixime + Moxifloxacin
Diarrhoea
Nausea
Abdominal pain
Headache
Dizziness
How Cefixime + Moxifloxacin works
- Cefixime + Moxifloxacin is a potent antibiotic combination.
- Cefixime, a third-generation cephalosporin, inhibits the bacterial cell wall synthesis. It stops the last step of transpeptidation, affecting the cross-linkage of peptidoglycan chains, which are essential for the strength and rigidity of bacterial cell walls.
- Moxifloxacin, a fluoroquinolone antibiotic, inhibits two enzymes called DNA gyrase and topoisomerase IV, which are crucial for bacterial DNA replication, transcription, repair, and recombination. By blocking these enzymes, Moxifloxacin effectively kills bacteria and halts the infection.
- Together, Cefixime and Moxifloxacin work in synergy to provide broad-spectrum coverage against various gram-positive and gram-negative bacteria, helping to prevent the development of antibiotic resistance.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
- Cefixime + Moxifloxacin is available for oral use in the form of tablets.
Age and Dose Restrictions
- This combination is meant for adults, and children above 12 years of age.
Contraindications
- This combination is contraindicated in patients with known allergies to cefixime, moxifloxacin, or any other cephalosporin or quinolone antibiotic.
- It is also contraindicated in patients with a history of cholestatic jaundice or hepatic dysfunction associated with prior use of Cefixime.
Other Medications to Avoid
- This combination may interact with antacids, sucralfate, multivitamins, and other products containing magnesium, aluminium, iron or zinc.
- It may also interact with anticoagulants (like warfarin), and antiarrhythmics (like amiodarone).
Overdose and Missed Dose
- An overdose of this medication may cause symptoms like confusion, dizziness, seizures, and hallucinations. If you observe these symptoms, inform your doctor immediately.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular dose schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and can resolve upon discontinuation of this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
- Drinking plenty of water may help manage common side effects like diarrhoea or dry mouth.
- Resting or avoiding extreme physical activity can help manage fatigue.
- Sitting or lying down can help manage dizziness.
Use in Driving and Operating Machinery
- This combination may cause drowsiness or blur your vision. Avoid driving or operating heavy machinery if you experience these side effects.
Use in Pregnancy and Lactation
- Consult your doctor before using this medicine during pregnancy or while breastfeeding.
Caution in Other Conditions
- Patients with renal or hepatic impairment should exercise caution when taking this medicine. Dose adjustment may be required in such cases.
Special Dietary and Lifestyle Recommendations
- Avoid excessive intake of caffeine, as it may increase certain side effects of Cefixime.
- Regular exercise can help strengthen your immune system and reduce the risk of bacterial infections.
Frequently asked questions
Is Cefixime + Moxifloxacin a steroid?
No, Cefixime + Moxifloxacin is not a steroid. It is a combination of two antibiotics that are used to manage various bacterial infections.
Does Cefixime + Moxifloxacin affect fertility?
Cefixime + Moxifloxacin is not associated with affecting fertility in humans. However, if you have concerns, it is best to consult your doctor.
Can I stop taking Cefixime + Moxifloxacin when I feel better?
No, it is important to take the complete course of antibiotics as recommended by your doctor. Even if you feel better, the infection may still be present in your body. Stopping the medicine early can lead to the infection returning or getting worse.
Does Cefixime + Moxifloxacin cause weight gain?
Cefixime + Moxifloxacin is not directly associated with causing weight gain. However, if you notice any unusual changes in your weight while taking this medicine, consult your doctor.
Does Cefixime + Moxifloxacin have any effect on sleep?
Cefixime + Moxifloxacin is not associated with affecting sleep disturbances. However, your sleep could be affected by the bacterial infection you are managing.
Is it safe to take Cefixime + Moxifloxacin daily?
Cefixime + Moxifloxacin should be taken as prescribed by your doctor, and it is safe for daily use for the duration advised by your doctor.
How much time does Cefixime + Moxifloxacin take to work?
The time for Cefixime + Moxifloxacin to start showing its effects can vary depending on the type and severity of the infection. However, symptom improvement is usually seen within 2-3 days of starting therapy.
Cefixime + Moxifloxacin in other salts
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