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Cefpodoxime

Uses of Cefpodoxime

  • The primary use of Cefpodoxime is to manage mild to moderate infections caused by susceptible bacteria. It is a third-generation cephalosporin antibiotic.

  • This medicine is also used to manage respiratory tract infections (such as bronchitis, pneumonia, pharyngitis, and tonsillitis), urinary tract infections, skin and soft tissue infections, gonorrhoea, and otitis media in children.

Side effects of Cefpodoxime

  • Diarrhoea

  • Nausea

  • Vomiting

  • Abdominal pain

  • Headache

How Cefpodoxime works

  • Cefpodoxime is a third-generation cephalosporin antibiotic.

  • It works by inhibiting bacterial cell wall synthesis, leading to the weakening and eventual death of the bacteria. Cefpodoxime is effective against a broad spectrum of gram-positive and gram-negative bacteria.

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Cefpodoxime is available for oral use in the form of tablets and an oral suspension. The tablets should be taken with food to enhance absorption, while the oral suspension can be taken with or without food.

Age and Dose Restrictions

  • Cefpodoxime is meant for both adults and children. Specifically, the oral suspension formulation is suitable for paediatric patients.

Contraindications

  • Cefpodoxime is contraindicated in patients with a known hypersensitivity to cephalosporins.

  • Those with severe renal impairment must also avoid this medication unless dose adjustments are made.

Other Medications to Avoid

  • This medicine may interact with aminoglycosides (such as gentamicin and tobramycin), loop diuretics (like furosemide), antacids (such as aluminium hydroxide), H2-receptor antagonists (like ranitidine), and proton pump inhibitors (such as omeprazole).

  • Before starting any new medications, it is crucial to consult a doctor, especially if using anticoagulants like warfarin which might have their effects potentiated by Cefpodoxime.

Overdose and Missed Dose

  • An overdose of Cefpodoxime may require monitoring for adverse reactions; supportive treatment is recommended. Hemodialysis can remove Cefpodoxime from the body efficiently in cases of significant overdose.

  • If you miss a dose of Cefpodoxime, take it as soon as you remember unless it is almost time for your next scheduled dose. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing gastrointestinal upset, taking the medicine with meals might help.

  • Staying hydrated can help manage minor side effects like dry mouth or mild diarrhoea.

Use in Driving and Operating Machinery

  • Cefpodoxime may cause dizziness or drowsiness in some individuals. It is advisable to avoid driving or operating heavy machinery if you experience these symptoms after taking the medicine.

Use in Pregnancy and Lactation

  • Cefpodoxime falls under pregnancy category B, which means it should only be used during pregnancy if clearly needed. It is excreted in human milk, so caution is advised when administering this medicine to nursing mothers.

  • Always consult your doctor before using this medicine during pregnancy or lactation.

Caution in Other Conditions

  • Patients with kidney problems need to have their dosage adjusted according to their renal function since Cefpodoxime is predominantly eliminated by the kidneys.

  • Those with a history of colitis should use Cefpodoxime cautiously as it may exacerbate this condition.

Special Dietary and Lifestyle Recommendations

  • For patients managing infections treated by Cefpodoxime, maintaining adequate hydration is crucial. Drinking plenty of fluids can help eliminate bacteria from the urinary tract.

  • A balanced diet rich in nutrients can support the immune system in fighting infections.

  • Adequate rest is recommended during the period of treatment to aid recovery.

  • Avoiding excessive sugars and spicy foods may help mitigate some gastrointestinal side effects associated with antibiotic therapy.

Frequently asked questions

Cefpodoxime tablets must be taken as specified by your doctor.

Certain people may experience dizziness as a side effect of Cefpodoxime, which could make them feel tired. If you experience severe fatigue, consult your doctor.

Cefpodoxime should be used cautiously in patients with a history of penicillin allergy, as there is a risk of cross-reactivity. Always inform your doctor about any allergies before starting a new medication.

Cefpodoxime does not typically affect mood or behaviour. However, some people may experience headaches or dizziness, which could indirectly influence their mood. Talk to your doctor if you have any concerns.

It is generally recommended to avoid alcohol while taking Cefpodoxime, as alcohol may increase the risk of side effects such as dizziness, upset stomach, or impaired judgment. Always consult your doctor for personalised advice.

Long-term use of any antibiotic, including Cefpodoxime, may increase the risk of developing a secondary infection due to bacterial resistance. Your doctor will prescribe the appropriate duration for you.

Yes, Cefpodoxime is available as an oral tablet or suspension under various brand names.

Terms & Conditions


Available medicines for CEFPODOXIME
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