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Cefpodoxime Proxetil + Dicloxacillin

Uses of Cefpodoxime Proxetil + Dicloxacillin

  • Cefpodoxime Proxetil + Dicloxacillin is used to manage various types of bacterial infections. This medicine belongs to the group of antibiotics, encompassing two types: third-generation cephalosporins and penicillin-type antibiotics.

Side effects of Cefpodoxime Proxetil + Dicloxacillin

  • Diarrhoea

  • Nausea

  • Vomiting

  • Abdominal pain

  • Skin rash

How Cefpodoxime Proxetil + Dicloxacillin works

  • Cefpodoxime Proxetil + Dicloxacillin is a combination of two antibiotics.

  • Cefpodoxime Proxetil is a third-generation cephalosporin antibiotic. It functions by inhibiting the synthesis of bacterial cell walls. It attaches to and deactivates enzymes known as penicillin-binding proteins, playing a crucial role in the formation of bacterial cell walls. Consequently, this interruption results in the rupture and death of bacterial cells.

  • Dicloxacillin, a penicillin-type antibiotic, also hinders the synthesis of bacterial cell walls but via a slightly different mechanism. It attaches to and deactivates transpeptidase enzymes that are responsible for interlinking peptidoglycans in the bacterial cell wall. This weakens the cell wall, causing the bacteria to burst open and die.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Cefpodoxime Proxetil + Dicloxacillin is available in the form of tablets for oral administration.

Age and Dose Restrictions

  • This combination is suitable for adults and children above the age of 12 years.

Contraindications

  • This medication is contraindicated in individuals with known hypersensitivity to cefpodoxime, dicloxacillin, other cephalosporins, penicillins, or any component of the formulation.

  • It should not be taken by patients with a history of severe hypersensitivity reactions to beta-lactam antibiotics.

Other Medications to Avoid

  • Cefpodoxime Proxetil + Dicloxacillin may interact with several medications, including other antibiotics (such as penicillin or tetracyclines), antacids (like magnesium or aluminium hydroxide), and anticoagulants (such as warfarin).

Overdose and Missed Dose

  • Overdosing on this medication may lead to nausea, vomiting, epigastric distress, and diarrhoea. If such symptoms arise, discontinue the medication and get medical help immediately.

  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, ignore the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage diarrhoea.

  • Eating small, frequent meals can help manage nausea and vomiting.

  • Resting or getting enough sleep can help manage headaches.

  • Avoiding spicy or fatty foods can reduce abdominal pain and dyspepsia.

Use in Driving and Operating Machinery

  • Cefpodoxime Proxetil + Dicloxacillin may cause dizziness. If affected, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • The safety of this medicine during pregnancy and lactation has not been established. It is advised to consult your doctor if you are pregnant or breastfeeding before using this medication.

Caution in Other Conditions

  • Patients with a history of gastrointestinal diseases, particularly colitis, should be cautious when using this medication.

  • Individuals with renal or hepatic impairment should consult their doctor before starting this medication, as dose adjustments may be necessary.

Special Dietary and Lifestyle Recommendations

  • Follow good hygiene practices to prevent recurrent infections.

  • Maintain a balanced diet rich in vitamins, minerals, and proteins to strengthen the immune system.

  • Keep yourself hydrated by drinking plenty of fluids.

  • Get sufficient rest and sleep to help your body fight off infections more effectively.

  • Avoid smoking and alcohol as it can weaken your immune system and make you more susceptible to infections.

Frequently asked questions

No, Cefpodoxime Proxetil + Dicloxacillin is not a steroid. It is a combination of two antibiotics used to manage several types of bacterial infections.

There are no specific side effects of Cefpodoxime Proxetil + Dicloxacillin directly affecting sleep. However, if you experience sleep disturbances after starting the medicine, consult your doctor.

Cefpodoxime Proxetil + Dicloxacillin does not have any known effects on fertility. If you are planning a pregnancy, it is advisable to consult your doctor.

There are no specific diet restrictions while taking Cefpodoxime Proxetil + Dicloxacillin. However, the medication should be taken with food to enhance absorption.

Cefpodoxime Proxetil + Dicloxacillin should be taken as per the doctor's prescription, usually every 12 hours for 7-10 days, based on the type and severity of the infection.

The time it takes for Cefpodoxime Proxetil + Dicloxacillin to work can vary depending on the infection being managed. It is important to continue the medication for the entire duration prescribed by your doctor, even if you feel better.

Cefpodoxime Proxetil + Dicloxacillin should be taken as directed by your doctor, usually every 12 hours. It should be taken with food to enhance absorption.

Terms & Conditions


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