The primary use of Ceftazidime is to manage various bacterial infections, including complicated intra-abdominal infections (cIAI), complicated urinary tract infections (cUTI), respiratory tract infections, bone and joint infections, skin and soft tissue infections, bacterial meningitis, and septicaemia. Ceftazidime is a third-generation cephalosporin antibiotic.
Additionally, it is also used to prevent infections in patients undergoing certain types of surgery, such as prostate or abdominal surgeries.
Injection site reactions
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Ceftazidime is a third-generation cephalosporin antibiotic.
It combats bacterial infections by impeding the formation of the bacterial cell wall, a crucial structure for bacterial survival and growth. Ceftazidime achieves this by binding to specific enzymes known as penicillin-binding proteins (PBPs) that play a key role in creating peptidoglycan, a significant component of the cell wall. When these proteins are inhibited, it disrupts the synthesis of the cell wall, leading to the eventual breakdown and death of the harmful bacteria.
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Ceftazidime is available for administration via intramuscular (injection) and intravenous (infusion) routes.
This medicine is intended for use in adults as well as children.
Ceftazidime is contraindicated for individuals who have a known hypersensitivity to this medicine or other cephalosporins.
It should be used with caution in patients with a history of penicillin allergy, due to potential cross-reactivity.
Ceftazidime may interact with aminoglycosides (such as gentamicin and neomycin) and broad-spectrum antibiotics (such as chloramphenicol).
In cases of overdose, it's important to maintain adequate hydration and monitor renal function. Hemodialysis or peritoneal dialysis may facilitate the removal of Ceftazidime from the body.
If you miss a dose, take it as soon as you remember it. However, avoid doubling up on doses to catch up.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Try applying a cool compress to the injection site area.
Drinking plenty of fluids can also help manage some of these side effects.
Ceftazidime may cause dizziness or other side effects that could affect your ability to drive or operate machinery. If you experience these symptoms, avoid these activities until you know how the medication affects you.
Ceftazidime is categorised as a pregnancy category B medicine, which indicates that it should be used during pregnancy only if clearly needed and as the medicine is excreted in human milk in low concentrations, it should be used with caution in nursing mothers.
Patients with renal impairment should exercise caution when taking this medicine, as dosage adjustments are necessary to prevent the accumulation of Ceftazidime in the body.
Prolonged use of Ceftazidime may lead to an overgrowth of non-susceptible organisms, including fungi.
Maintain good hydration to help manage potential side effects such as gastrointestinal disturbances.
Regular hand washing and maintaining a clean environment can help prevent bacterial infections, which Ceftazidime is used to manage.
Frequently asked questions
No, weight gain or loss is not a common side effect of Ceftazidime. However, each person may react differently to any medication, so if you notice any significant changes in your weight, consult your doctor.
Ceftazidime is not directly associated with affecting sleep. However, if you experience any changes in your sleep patterns while on this medicine, you should consult your doctor immediately.
Ceftazidime is not directly associated with affecting fertility. However, if you are planning a pregnancy or have concerns about fertility, discuss these with your doctor.
Ceftazidime does not typically have any impact on mood or behaviour. If you experience unusual mood changes or behaviours after using this medication, consult your doctor immediately.
The safety of daily use of Ceftazidime depends on the nature and severity of the infection being managed. Your doctor will prescribe an appropriate dosage schedule based on your specific needs.
The time for Ceftazidime to start working can vary depending on the type and severity of the infection being managed. You should start noticing an improvement in your symptoms within a few days, but it is essential to complete the entire prescribed course for optimal results.
Ceftazidime is a prescription medicine and is not available over the counter.
Ceftazidime in other salts
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