Ceftazidime + Sulbactam

Dosage Forms Available

• Ceftazidime + Sulbactam is available as an injectable powder. It is administered through either the intramuscular or the intravenous route depending on the severity of infection and the doctor's discretion.

Age and Dose Restrictions

• This medicine is meant for adults and children above 12 years of age.

Contraindications

• This medicine is contraindicated in patients with known severe hypersensitivity to Ceftazidime, Sulbactam, other cephalosporins, penicillins, or beta-lactamase inhibitors.

• It is also contraindicated in individuals with a previous history of Ceftazidime-associated cholestatic jaundice or hepatic dysfunction.

Other Medications to Avoid

• Ceftazidime + Sulbactam may interact with uricosuric medicines (like probenecid, sulfinpyrazone), aminoglycoside antibiotics (such as gentamicin, amikacin) and Amphenicol-class Antibacterial (like chloramphenicol, thiamphenicol).

Overdose and Missed Dose

• An overdose of Ceftazidime + Sulbactam may cause neurological reactions such as seizures. Hemodialysis can remove these substances from the body, and symptomatic treatment is recommended if an overdose occurs.

• If you forget to administer this medicine, administer it as soon as you remember. However, if it is near the time for the next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage side effects such as diarrhoea and vomiting. It can also help to prevent kidney damage from the medicine.

• Resting or sitting in a comfortable position can help manage injection site reactions.

Use in Driving and Operating Machinery

• Ceftazidime + Sulbactam does not commonly affect the ability to drive or operate machinery. However, if you experience side effects such as dizziness or confusion after administering this medication, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Ceftazidime + Sulbactam falls under pregnancy category B, meaning it can be used during pregnancy only if needed. Low concentrations are excreted in breast milk, so caution is needed when administering to nursing women.

Caution in Other Conditions

• Patients with kidney impairment may need dosage adjustments as both Ceftazidime and Sulbactam are eliminated by the kidneys.

• Those with a history of gastrointestinal disease, especially colitis, should also exercise caution as this medication could potentially exacerbate these conditions.

Special Dietary and Lifestyle Recommendations

• Consuming a balanced diet rich in fruits, vegetables, lean proteins, and whole grains can support overall health and well-being, crucial for individuals battling bacterial infections.

• Regular sleep is important to support immune function and recovery from infection.