Ceftriaxone + Vancomycin
Uses of Ceftriaxone + Vancomycin
Ceftriaxone + Vancomycin is primarily used to manage serious bacterial infections, including infections caused by gram-positive and gram-negative bacteria. This combination belongs to the antibiotic group of medicines.
It is also indicated for use in various conditions such as severe respiratory tract infections like pneumonia, complicated skin and soft tissue infections, bone and joint infections like osteomyelitis, intra-abdominal infections, urinary tract infections, bacterial sepsis and septic shock, bacterial meningitis, and endocarditis prophylaxis for dental procedures in high-risk patients.
Side effects of Ceftriaxone + Vancomycin
Diarrhoea
Nausea
Vomiting
Headache
Rash and itching
How Ceftriaxone + Vancomycin works
- Ceftriaxone belongs to the cephalosporin antibiotics class of medicines. It destroys bacteria by disrupting their cell wall formation. It binds to specific proteins in the bacteria that are essential for building the cell wall. When these proteins are unable to function, the cell wall weakens and eventually breaks apart, leading to the death of the bacteria.
- Vancomycin is a glycopeptide antibiotic that combats bacteria by binding to the molecules involved in building the bacterial cell wall. This action prevents these molecules from being integrated into the wall, resulting in a weakened structure that is susceptible to bursting.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BDS, PGCAD, GMHE (IIM-B)
Expert Advice
Dosage Forms Available
- Ceftriaxone + Vancomycin is available in the infusion (intravenous ) route.
Age and Dose Restrictions
- This medicine is meant for adults and children.
Contraindications
- This medicine is contraindicated in patients with known allergies to either ceftriaxone or vancomycin.
- It is also contraindicated in patients who have had previous severe hypersensitivity reactions to any cephalosporin or glycopeptide antibiotic.
Other Medications to Avoid
- This medicine may interact with diuretics (eg., furosemide), aminoglycosides (eg., gentamicin, tobramycin, amikacin), anticoagulants (eg., warfarin), and neuromuscular blockers (eg., pancuronium).
Overdose and Missed Dose
- The chances for an overdose of this medicine are less as it is administered to you by a healthcare professional. However, symptoms of overdosage may include seizures, severe vomiting, or an allergic reaction. Immediate medical attention should be sought if any such symptoms are noticed.
- If a dose is missed, consult your healthcare provider for the next dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor. Some tips include:
- Drink plenty of water to combat side effects like nausea and vomiting.
- Rest and relaxation can help manage headaches.
- Cool compresses can provide some relief for skin reactions like rashes and itching.
Use in Driving and Operating Machinery
- This medicine can affect your ability to drive or operate heavy machines. Avoid these activities if you experience dizziness after taking this medicine.
Use in Pregnancy and Lactation
- This medicine is recommended to be used during pregnancy and breastfeeding only if recommended by a healthcare professional. Always consult your doctor before taking this medicine during pregnancy and lactation.
Caution in Other Conditions
- Patients with renal impairment should exercise caution when taking this medicine and may require dose adjustments.
Special Dietary and Lifestyle Recommendations
- Maintain good personal hygiene to reduce the risk of bacterial infections.
- Stay hydrated and maintain a balanced diet to support overall health.
- Avoid close contact with individuals with infectious conditions, as this combination is used for severe infections.
- Regular check-ups with the doctor are advised when using this combination to monitor progress and adjust dosage if necessary.
Frequently asked questions
Is Ceftriaxone + Vancomycin a steroid?
No, Ceftriaxone + Vancomycin is not a steroid. Ceftriaxone belongs to a class of antibiotics known as third-generation cephalosporins, while Vancomycin is classified as a glycopeptide antibiotic. Together, they work to kill or prevent the growth of bacteria causing the infection.
Does Ceftriaxone + Vancomycin have any effect on sleep?
There is no direct evidence to suggest that Ceftriaxone + Vancomycin affects sleep. However, if you experience unusual symptoms like insomnia or excessive sleepiness after starting this medication, you should inform your doctor immediately.
Will Ceftriaxone + Vancomycin affect fertility?
There is no scientific proof indicating that the use of Ceftriaxone + Vancomycin could impact fertility in both men and women. If you have concerns about this, it is better to consult your doctor.
Does Ceftriaxone + Vancomycin cause weight gain?
Weight gain is not a commonly reported side effect of Ceftriaxone + Vancomycin. However, if you notice unusual weight gain while taking this medicine, consult your doctor.
Is it safe to take Ceftriaxone + Vancomycin daily?
Ceftriaxone + Vancomycin should be administered according to the doctor’s instructions, based on the type and severity of the infection. It is not recommended to self-administer this combination without medical advice.
How much time does Ceftriaxone + Vancomycin take to work?
The time taken for Ceftriaxone + Vancomycin to act can vary depending on the type and severity of the infection. Your symptoms should improve within a few days of starting the treatment, but it is essential to complete the entire course as advised by your doctor.
What is the best time to take Ceftriaxone + Vancomycin?
Ceftriaxone + Vancomycin is administered intravenously and the dosing schedule will be decided by your healthcare team based on the type and severity of your infection. It is crucial to follow their directions for the most effective results.
Ceftriaxone + Vancomycin in other salts
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