Home/Drugs By Ailments / Chlorbutol + Phenylephrine + Tropicamide

Chlorbutol + Phenylephrine + Tropicamide

Uses of Chlorbutol + Phenylephrine + Tropicamide

  • The primary use of Chlorbutol + Phenylephrine + Tropicamide is for procedures requiring dilation of the pupil and paralysis of the ciliary muscles, allowing comprehensive examination of the eye. It falls in the category of ophthalmic solutions.

  • Additionally, it is indicated for pre-and post-operative dilation of the pupil in ophthalmic procedures like cataract surgery.

Side effects of Chlorbutol + Phenylephrine + Tropicamide

  • Stinging or discomfort

  • Blurred vision

  • Light sensitivity

  • Dry mouth

How Chlorbutol + Phenylephrine + Tropicamide works

  • Chlorbutol is included as an antimicrobial preservative. It aids in preventing bacterial growth and prolongs the shelf life of the solution. It may also have a slight local anaesthetic effect.

  • Phenylephrine is an adrenergic agonist. It triggers the alpha-1 receptors on the iris dilator muscle, causing the pupil to widen. Additionally, it constricts blood vessels to reduce redness in the eye.

  • Tropicamide is an anticholinergic. It blocks acetylcholine receptors on the iris sphincter and ciliary muscle. This allows the iris dilator to further widen the pupil and causes a temporary paralysis of accommodation.

Certified content

Written By

docImg
Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Chlorbutol + Phenylephrine + Tropicamide is available for use via the ocular route as an ophthalmic solution.

Age and Dose Restrictions

  • This combination is designed for use by adults and children when prescribed by a doctor.

Contraindications

  • Chlorbutol + Phenylephrine + Tropicamide is contraindicated in patients with narrow-angle glaucoma and hypersensitivity to any component of the formulation.

Other Medications to Avoid

  • Chlorbutol + Phenylephrine + Tropicamide may interact with monoamine oxidase inhibitors (such as phenelzine and tranylcypromine), tricyclic antidepressants (including amitriptyline and clomipramine), and beta-blockers (such as propranolol and atenolol).

Overdose and Missed Dose

  • An overdose of Chlorbutol + Phenylephrine + Tropicamide can lead to severe hypertension, reflex bradycardia, headaches, nausea, tremors, and sweating. Immediate medical intervention is necessary.

  • If you miss a dose of this combination, use it as soon as possible but do not double the dosage.

  • In case you happen to put a few extra drops of this combination in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

Management of Side Effects

Most side effects are temporary, generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dry mouth, staying well-hydrated by drinking sufficient water can be helpful.

  • If experiencing blurred vision, avoid engaging in activities requiring sharp visual acuity until the effect wears off.

Use in Driving and Operating Machinery

  • Chlorbutol + Phenylephrine + Tropicamide may impair your ability to drive or operate heavy machinery due to potential vision blurriness and light sensitivity. It is advisable to avoid these activities until your vision has cleared.

Use in Pregnancy and Lactation

  • The safety of using Chlorbutol + Phenylephrine + Tropicamide during pregnancy or while breastfeeding has not been fully established. It is advised to consult a doctor before using this combination in these conditions.

Caution in Other Conditions

  • Special caution should be exercised when using Chlorbutol + Phenylephrine + Tropicamide in patients with cardiovascular diseases such as hypertension or heart conditions due to the effects of phenylephrine on blood pressure and heart rate.

Special Dietary and Lifestyle Recommendations

  • Wearing sunglasses may help manage light sensitivity experienced after using Chlorbutol + Phenylephrine + Tropicamide.

  • Ensure you maintain a calm environment at home or work to help manage any transient visual disturbances or discomfort.

  • It may be beneficial to arrange transportation if planning to travel after application due to potential temporary vision impairments.

  • Regular eye check-ups can help monitor and manage any ongoing eye health issues effectively.

Frequently asked questions

No, Chlorbutol + Phenylephrine + Tropicamide is not a steroid. This combination comprises a preservative (Chlorbutol), a decongestant that also aids pupil dilation (Phenylephrine), and an anticholinergic that helps to dilate the pupil and temporarily paralyse accommodation (Tropicamide).

There is no direct mention in the provided references that this combination impacts sleep. However, visual disturbances caused by pupil dilation might affect routine activities until the effect wears off.

The references provided do not indicate any effects of Chlorbutol + Phenylephrine + Tropicamide on fertility. Consult your doctor for personalised advice.

There are no specific dietary restrictions mentioned in the provided references while using this combination unless instructed by your doctor.

This combination is used primarily for procedures requiring pupil dilation and paralysis of the ciliary muscle; as such, it is typically not meant for daily use unless prescribed by your doctor.

The effects of this combination begin within 10-30 minutes after administration and last for several hours.

This combination is typically used during an eye examination or prior to an ophthalmic procedure; therefore, it should be administered as directed by your doctor.

Terms & Conditions


Chlorbutol + Phenylephrine + Tropicamide in other salts

CETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEPHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINETROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINECAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE
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