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Chlordiazepoxide + Clidinium

Uses of Chlordiazepoxide + Clidinium

  • The primary use of Chlordiazepoxide + Clidinium is to manage various gastrointestinal disorders including irritable bowel syndrome (IBS), stomach ulcers, and acute enterocolitis. It belongs to the group of benzodiazepine and anticholinergic medications.

  • In addition, this combination has a dual role in not only relieving abdominal cramping and spasms but also reducing anxiety and emotional stress, which can further aggravate symptoms of these gastrointestinal disorders.

Side effects of Chlordiazepoxide + Clidinium

  • Drowsiness

  • Dizziness

  • Dry mouth

  • Constipation

  • Nausea

How Chlordiazepoxide + Clidinium works

  • Chlordiazepoxide is a benzodiazepine. It enhances the effect of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA). This neurotransmitter slows down brain activity, leading to a reduction in anxiety and tension.

  • Clidinium is an anticholinergic. It works by relaxing the smooth muscles in your stomach and intestines. It does this by blocking the action of a chemical messenger, acetylcholine, which can help reduce muscle spasms and pain in the gut.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Chlordiazepoxide + Clidinium can be taken orally (tablet and capsule).

Age and Dose Restrictions

  • This combination medicine is intended for use by adults aged 18 and above.

Contraindications

  • Chlordiazepoxide + Clidinium is contraindicated in patients with known hypersensitivity to benzodiazepines or anticholinergics. It is also contraindicated in patients with bowel obstruction, severe constipation, and myasthenia gravis.

Other Medications to Avoid

  • Chlordiazepoxide + Clidinium may interact with other CNS depressants such as opioids (like morphine), sedatives (like diazepam), antidepressants (like fluoxetine), anticholinergics (like atropine), antifungals (such as ketoconazole and itraconazole), and cardiac glycosides (like digoxin).

Overdose and Missed Dose

  • An overdose of Chlordiazepoxide + Clidinium may lead to severe drowsiness, confusion, slow reflexes, coma, and respiratory depression. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of this medication, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For dry mouth, nose, and throat, try to stay hydrated by drinking plenty of water.

  • To manage constipation, increase your intake of high-fibre foods and ensure you are well-hydrated.

  • If you experience drowsiness or dizziness, avoid activities that require mental alertness until these symptoms subside.

Use in Driving and Operating Machinery

  • Chlordiazepoxide + Clidinium may cause drowsiness or dizziness. Therefore, it is advisable to avoid driving or operating heavy machinery if you experience these side effects after taking this medication.

Use in Pregnancy and Lactation

  • Chlordiazepoxide + Clidinium should only be used during pregnancy or lactation if the potential benefits outweigh the potential risks to the baby. It is recommended to consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with narrow-angle glaucoma, enlarged prostate, severe respiratory insufficiency, or liver or kidney disease need to exercise caution when using Chlordiazepoxide + Clidinium. Always consult your doctor before starting any new medication.

Special Dietary and Lifestyle Recommendations

  • It is also beneficial to practise stress management techniques such as yoga, meditation, or deep breathing exercises, as stress can aggravate gastrointestinal symptoms.

Frequently asked questions

Yes, there is a potential risk of dependence with long-term use of Chlordiazepoxide + Clidinium. It should be used cautiously and always under the supervision of a doctor.

Yes, Chlordiazepoxide, a component in this combination, has a calming effect that can reduce anxiety and emotional tension.

Chlordiazepoxide + Clidinium should be taken for the duration as prescribed by your doctor. Prolonged use of this medication may lead to dependency and withdrawal symptoms upon discontinuation.

No, abrupt discontinuation of Chlordiazepoxide + Clidinium, especially after prolonged use, can lead to withdrawal symptoms and rebound effects. Always stop the medication under the supervision of your doctor.

This medicine may potentially cause weight changes. However, it is not generally associated with significant weight gain.

Chlordiazepoxide, one component of this combination, can be habit-forming if used for extended periods of time or at high doses. Therefore, it should only be taken exactly as directed by your doctor.

No, Chlordiazepoxide + Clidinium is not an over-the-counter medication and requires a prescription from a doctor.

Terms & Conditions


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