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Chlorhexidine Gluconate + Metronidazole

Uses of Chlorhexidine Gluconate + Metronidazole

  • Chlorhexidine Gluconate + Metronidazole is primarily used to manage gum and mouth infections. This combination belongs to a group of medicines known as antiseptics and antibiotics.

  • It is also indicated for other conditions like gingivitis, periodontitis, mouth ulcers and lesions, and as an adjunct to dental procedures like scaling and root planing.

Side effects of Chlorhexidine Gluconate + Metronidazole

  • Brown staining of teeth and tongue

  • Altered taste sensation

  • Oral irritation

  • Dryness in the mouth

  • Nausea and vomiting

How Chlorhexidine Gluconate + Metronidazole works

  • Chlorhexidine Gluconate + Metronidazole is a combination wi antimicrobial and antibiotic properties.

  • Chlorhexidine Gluconate, being an antiseptic, adheres to the surfaces in your mouth, forming a protective layer that disrupts the structure of bacteria. This leads to the leakage of vital components from the bacterial cells, resulting in their death. It also prevents plaque build-up and inflammation of the gums.

  • Metronidazole, an antibiotic, enters bacterial cells and hampers their DNA synthesis. It is particularly effective against anaerobic bacteria that don't require oxygen to survive. By disrupting their DNA, it prevents these bacteria from growing and multiplying.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Chlorhexidine Gluconate + Metronidazole is available for topical use (gel and mouthwash).

Age and Dose Restrictions

  • This medicine is meant for adults and should not be used by children.

Contraindications

  • Chlorhexidine Gluconate + Metronidazole is contraindicated in patients with known hypersensitivity to either chlorhexidine gluconate or metronidazole.

  • It is also contraindicated in individuals with severe mucositis or stomatitis and those with intraoral wounds or ulceration.

Other Medications to Avoid

  • Chlorhexidine Gluconate + Metronidazole may interact with anticoagulants (such as warfarin, and heparin), antihistamines (such as cetirizine, loratadine), antifungal medications (such as ketoconazole, fluconazole), immunosuppressants (such as cyclosporine, tacrolimus), antidiabetic medications (such as insulin, metformin), and other antibiotics (such as ciprofloxacin, amoxicillin).

Overdose and Missed Dose

  • An overdose of Chlorhexidine Gluconate + Metronidazole might lead to increased severity of side effects such as nausea or oral irritation. If you suspect an overdose, rinsing the mouth thoroughly and consulting your doctor is advisable.

  • If you miss a dose, apply or use it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage brown staining of teeth, which might occur during treatment, consider using this medicine at bedtime when eating or drinking, as it will not occur immediately after.

  • For altered taste or dry mouth, rinsing with water can be helpful.

Use in Driving and Operating Machinery

  • Chlorhexidine Gluconate + Metronidazole does not impair your ability to drive or operate machinery since it is used locally in the mouth and does not have systemic effects that might influence your alertness or coordination.

Use in Pregnancy and Lactation

  • It is prudent to consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Although there are no specific restrictions for individuals with renal or hepatic conditions, it is always wise to inform your doctor about any chronic conditions you may have before starting any new medicinal regimen.

Special Dietary and Lifestyle Recommendations

  • Maintain good oral hygiene practices, including regular brushing, flossing, and dental check-ups to complement the effects of Chlorhexidine Gluconate + Metronidazole.

  • Consider reducing the intake of foods and beverages that can stain your teeth further (like coffee, tea, and red wine) while using this medicine.

  • Engage in regular dental cleanings to manage any possible staining from the medication.

  • Stay hydrated to help manage any dryness of your mouth that might occur when using this medicine.

  • Avoid smoking or using tobacco products as these can exacerbate oral health problems and potentially reduce the effectiveness of periodontal treatment.

Frequently asked questions

No, Chlorhexidine Gluconate + Metronidazole is not a steroid. It is a combination medication containing an antiseptic and an antibiotic, used to manage gum and oral infections.

There is no evidence to suggest that Chlorhexidine Gluconate + Metronidazole affects sleep. However, if you notice any changes in your sleep patterns while using this medicine, you should consult your doctor.

There are no studies indicating that Chlorhexidine Gluconate + Metronidazole affects fertility in humans. If you have concerns about fertility, you should discuss them with your doctor.

Yes, you should continue your regular oral hygiene routine while using this medicine. This includes brushing, flossing and regular dental check-ups.

Yes, one of the common side effects of this combination medicine is brown staining of the teeth and tongue. However, this is temporary and can be removed by a dental professional after the treatment ends.

Yes, you can use toothpaste while using this mouthwash. However, it is recommended to use the mouthwash at least half an hour after brushing to avoid any interaction between the toothpaste and the medicine.

No, it is not recommended to consume alcohol while using Chlorhexidine Gluconate + Metronidazole as it can increase the risk of side effects like nausea and vomiting.

Terms & Conditions


Available medicines for CHLORHEXIDINE GLUCONATE + METRONIDAZOLE
Metrohex Plus Gel 20gm
Metrohex Plus Gel 20gm
Dr. Reddys Laboratories Ltd
Pack of 20 GM
₹85.89
MRP ₹104.75
18.00% OFF
Orex M Gel 10 GM
Orex M Gel 10 GM
Yash Pharma Laboratories
Pack of 10 GM
₹15.73
MRP ₹19.18
18.00% OFF
Metrohex Gel 10gm
Metrohex Gel 10gm
Dr. Reddys Laboratories Ltd
Pack of 10 GM
₹36.22
MRP ₹44.17
18.00% OFF
Mugard Dg Gel 20gm
Mugard Dg Gel 20gm
Ajanta Pharma Ltd
Pack of 20 GM
₹32.43
MRP ₹65.00
50.10% OFF
Spark M Gel 20 GM
Spark M Gel 20 GM
Chemo Health Care Pvt Ltd
Pack of 20 GM
₹29.44
MRP ₹59.00
50.10% OFF

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