Home/Drugs By Ailments / Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine

Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine

Uses of Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine

  • The main use of the combination Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine is to provide temporary relief from symptoms of the common cold, flu, allergies, hay fever, and other upper respiratory allergies. It belongs to the class of antihistamines, cough suppressants, and decongestants.

  • Secondary uses include the management of sinus congestion and minor throat and bronchial irritation.

Side effects of Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine

  • Drowsiness

  • Dry mouth

  • Nausea

  • Constipation

  • Restlessness or excitability

How Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine works

  • Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine is a combination medicine used to manage symptoms of the common cold, flu, and allergies.

  • Chlorpheniramine Maleate is an antihistamine. It works by reducing the effects of histamine, a substance in the body that causes allergic symptoms. This brings relief from symptoms like a runny nose and sneezing.

  • Dextromethorphan is a cough suppressant. It works by reducing activity in the part of the brain that triggers coughing. This helps to suppress or lessen the intensity of the cough.

  • Phenylpropanolamine is a decongestant. It shrinks swollen nasal mucous membranes by causing vasoconstriction, which is a fancy term for narrowing of blood vessels. This makes it easier for air to pass through your nose, relieving congestion.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • The combination of Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine is available for use orally in the form of tablets and liquids.

Age and Dose Restrictions

  • This medication is meant for adults and children. However, children under 6 years of age should only use this medication under the supervision of a doctor.

Contraindications

  • This medicine is contraindicated in patients with known allergies to Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine

  • It is also contraindicated in patients with severe high blood pressure, severe heart disease, or hyperthyroidism.

Other Medications to Avoid

  • This combination may interact with monoamine oxidase inhibitors (such as selegiline, phenelzine), beta blockers (like atenolol, propranolol), tricyclic antidepressants (like amitriptyline), antihistamines (like diphenhydramine), medicines for Parkinson's disease (like levodopa), and medicines for lungs (theophylline).

Overdose and Missed Dose

  • Overdose symptoms may include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, hallucinations, fast or irregular heartbeat, fainting, seizures or coma. If you suspect an overdose, reach out to a medical professional immediately.

  • If you miss a dose of this medication, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and return to your regular schedule. Do not double up on doses to make up for a missed one.

Management of Side Effects

Most side effects of this medication are temporary and generally harmless, resolving when the medication is discontinued. However, if you experience any severe side effects or worsening symptoms, please consult your doctor. Here are some tips to manage common side effects:

  • Drink plenty of water to help with dry mouth.

  • Rest and avoid sudden moves to manage dizziness.

  • Chewing sugar-free gum may help with dry mouth.

Use in Driving and Operating Machinery

  • This medication may affect your ability to drive or operate heavy machinery due to potential side effects like drowsiness or dizziness. It is advised not to engage in these activities while on this medication.

Use in Pregnancy and Lactation

  • For pregnant and breastfeeding women, it is recommended to consult a doctor before using Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine.

Caution in Other Conditions

  • Patients with liver or kidney disease, breathing problems, glaucoma, or diabetes should use this medication with caution. Always inform your doctor if you have these conditions before starting this medication.

Special Dietary and Lifestyle Recommendations

  • To effectively manage cold, flu or allergy symptoms:

  • Aim to get plenty of rest.

  • Consume a balanced diet rich in fruits and vegetables that can boost your immune system.

  • Avoid allergens that trigger your symptoms.

  • Practice good hygiene habits such as washing hands regularly to prevent cold and flu.

Frequently asked questions

No, this combination is not a steroid. It consists of an antihistamine (Chlorpheniramine Maleate), a cough suppressant (Dextromethorphan), and a decongestant (Phenylpropanolamine).

Yes, drowsiness is a common side effect of this medicine due to the antihistamine content. It is advisable not to drive or operate machinery after taking this medication.

If you have diabetes, it is essential to consult your doctor before taking this medication, as Phenylpropanolamine can affect blood sugar levels.

Loss of appetite is a potential side effect of this medication. If you experience this or any other adverse effects, consult your doctor.

It is not recommended to consume alcohol while taking this medication as it may increase drowsiness and dizziness.

Yes, constipation is a possible side effect of this medicine. If it occurs, drinking plenty of fluids and eating a high-fibre diet may help.

Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine may interact with certain herbal supplements, especially those that affect the central nervous system, like St. John's Wort or Valerian, which can enhance drowsiness. Supplements that raise blood pressure, such as ginseng or licorice, may also increase the risk of side effects due to the phenylpropanolamine component. It's best to consult your doctor before combining this combination with herbal supplements.

Terms & Conditions


Chlorpheniramine Maleate + Dextromethorphan + Phenylpropanolamine in other salts

CHLORPHENIRAMINE MALEATEDEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDECPM + DEXTROMETHORPHAN + PHENYLPROPANOLAMINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINECPM + DEXTROMETHORPHAN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECPM + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEDEXTROMETHORPHANAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINEAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + CODEINEAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + SODIUM CITRATEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESINAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHAN HYDROBROMIDE + MENTHOLCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + MENTHOLCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHANAMYLMETACRESOL + DEXTROMETHORPHAN HYDROBROMIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDEBROMHEXINE + CHLORPHENIRAMINE + DEXTROMETHORPHANCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHANAMMONIUM CHLORIDE + CPM + DEXTROMETHORPHAN + GUAIFENESINAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINEDEXTROMETHORPHAN + TRIPROLIDINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESIN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + DEXTROMETHORPHANDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINEAMMONIUM CHLORIDE + BROMHEXINE + DEXTROMETHORPHAN + MENTHOLCETIRIZINE + DEXTROMETHORPHANCETIRIZINE + DEXTROMETHORPHAN + PSEUDOEPHEDRINEBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESINCHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLPROPANOLAMINECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMMONIUM CHLORIDE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINBROMHEXINE + CHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + GUAIFENESINCHLORPHENIRAMINE MALEATE + DIETHYLCARBAMAZINEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE
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