Chlorthalidone + Metoprolol
Uses of Chlorthalidone + Metoprolol
Chlorthalidone + Metoprolol is primarily used to manage hypertension (high blood pressure) and belongs to the classes of medications known as diuretics and beta-blockers.
Additionally, this combination may also be used to manage fluid retention (oedema) caused by various conditions such as heart failure, liver disease, and kidney disorders.
Side effects of Chlorthalidone + Metoprolol
Dizziness or lightheadedness
Tiredness
Headache
Upset stomach, nausea
Vomiting
How Chlorthalidone + Metoprolol works
Chlorthalidone is a diuretic, or "water pill". It helps your kidneys get rid of excess water and salt from your body. As the volume of fluid in your blood vessels goes down, so does your blood pressure.
Metoprolol is a beta-blocker. It works by slowing down your heart rate and relaxing your blood vessels. This helps to lower your blood pressure and reduces the workload on your heart. Together, these medicines work in a complementary way to manage high blood pressure effectively.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Chlorthalidone + Metoprolol is available for oral administration in the form of combination tablets.
Age and Dose Restrictions
This medicine is typically prescribed for adults and children above 18 years of age.
Contraindications
Chlorthalidone + Metoprolol is contraindicated in patients with severe bradycardia (very slow heart rate), certain heart blocks, or arrhythmias, cardiogenic shock, decompensated heart failure, severe liver disease, and acute asthma attack.
Other Medications to Avoid
This combination may interact with other blood pressure medications like ACE inhibitors (such as lisinopril, ramipril), ARBs (such as losartan, telmisartan), diuretics (like furosemide, torsemide), NSAIDs (like ibuprofen and naproxen) and antidepressants (like fluoxetine and bupropion)
Overdose and Missed Dose
An overdose of Chlorthalidone + Metoprolol can lead to severe low blood pressure, slow or irregular heartbeat, shortness of breath, confusion and seizures. Immediate medical attention is required.
If you miss a dose of this medication, take it as soon as you remember. But if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Balance adequate fluid intake to avoid dehydration due to excessive urination.
Rise slowly from a sitting or lying position to reduce dizziness.
Use in Driving and Operating Machinery
Chlorthalidone + Metoprolol may cause dizziness, tiredness, or affect your vision. If you experience these effects, avoid driving or operating machinery until you feel safe to do so.
Use in Pregnancy and Lactation
Chlorthalidone + Metoprolol should be used during pregnancy and lactation only if the potential benefit justifies the risk. Always consult your doctor before using this medicine during pregnancy and breastfeeding.
Caution in Other Conditions
Patients with asthma, COPD, liver impairment, gout, lupus, severe allergies, and diabetes need to exercise caution while taking Chlorthalidone + Metoprolol.
Special Dietary and Lifestyle Recommendations
Patients are advised to maintain a low sodium and low cholesterol diet to manage hypertension.
Regular physical activity is recommended as it helps in controlling blood pressure levels.
Frequently asked questions
Can Chlorthalidone + Metoprolol cause weight gain?
Chlorthalidone + Metoprolol is not typically associated with weight gain. Metoprolol, a beta-blocker, may cause slight weight gain in some people, but this is not common. Chlorthalidone, a diuretic, usually causes fluid loss rather than weight gain.
Is Chlorthalidone + Metoprolol safe for long-term use?
Yes, Chlorthalidone + Metoprolol can be used for long-term management of hypertension, as prescribed by your doctor. Regular monitoring and blood tests will be required to ensure the medication's efficacy and safety.
Will I experience withdrawal symptoms if I stop taking Chlorthalidone + Metoprolol?
Chlorthalidone + Metoprolol should not be stopped abruptly without consulting your doctor. A sudden cessation can cause a rebound increase in blood pressure and other withdrawal symptoms.
Can Chlorthalidone + Metoprolol cause mood changes?
While it's rare, some people may experience mood changes like confusion or feeling depressed when taking Chlorthalidone + Metoprolol. If you notice such changes, it's important to consult your doctor immediately.
Is it possible to have an allergic reaction to Chlorthalidone + Metoprolol?
Yes, although rare, an allergic reaction to Chlorthalidone + Metoprolol can occur. Symptoms might include difficulty breathing, hives or swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, seek medical attention immediately.
Can Chlorthalidone + Metoprolol cause changes in menstruation?
Chlorthalidone + Metoprolol is not associated with changes in menstruation. They are primarily used to manage blood pressure and heart conditions, with no known effects on the menstrual cycle.
Can Chlorthalidone + Metoprolol be used for weight loss?
No, Chlorthalidone + Metoprolol is not indicated for weight loss. It is a combination medicine used to manage hypertension or high blood pressure. It is essential to discuss any weight loss plans with your doctor as abrupt weight changes can impact your blood pressure.
Chlorthalidone + Metoprolol in other salts
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