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Chlorthalidone + Olmesartan Medoxomil

Uses of Chlorthalidone + Olmesartan Medoxomil

  • The primary use of Chlorthalidone + Olmesartan Medoxomil is for the management of hypertension. It belongs to the category of diuretic and angiotensin II receptor blocker medications.

  • Additionally, this combination may also be used to manage fluid retention related to various conditions such as heart failure or liver/kidney disease.

Side effects of Chlorthalidone + Olmesartan Medoxomil

  • Lightheadedness

  • Headache

  • Fatigue

  • Nausea

  • Diarrhoea

How Chlorthalidone + Olmesartan Medoxomil works

  • Chlorthalidone is a thiazide-like diuretic. This means it increases the amount of urine your body produces, helping to remove excess fluid and salt. It reduces the volume of fluid in your blood vessels, which can cause high blood pressure.

  • Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB). Olmesartan allows your blood vessels to widen. This reduces the pressure inside them, making it easier for your heart to pump blood around your body.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Chlorthalidone + Olmesartan Medoxomil is available as tablets for oral use.

Age and Dose Restrictions

  • This medicine is meant for use in adults.

Contraindications

  • Chlorthalidone + Olmesartan Medoxomil is contraindicated in patients with severe kidney disease or inability to urinate. It is also contraindicated for individuals who have a known allergy to sulfa medicines, chlorthalidone, or olmesartan.

Other Medications to Avoid

  • This combination may interact with diuretics (such as spironolactone and amiloride), ACE inhibitors or aliskiren (like enalapril and lisinopril), NSAIDs (including ibuprofen and naproxen), antipsychotics (lithium), heart medications (digoxin), and bile acid sequestrants (such as cholestyramine and colestipol).

Overdose and Missed Dose

  • An overdose of Chlorthalidone + Olmesartan Medoxomil may cause severe dizziness, dehydration, electrolyte imbalance, or low blood pressure. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For dizziness or lightheadedness caused by this medication, ensure you rise slowly from sitting or lying positions.

  • Staying hydrated can help manage mild nausea; drink plenty of fluids throughout the day.

Use in Driving and Operating Machinery

  • Chlorthalidone + Olmesartan Medoxomil may cause dizziness or lightheadedness. You should avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Chlorthalidone + Olmesartan Medoxomil is not recommended during pregnancy due to the risk of harm to the foetus. It should be used with caution during breastfeeding. Always consult your doctor before use if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Caution is advised when using Chlorthalidone + Olmesartan Medoxomil in patients with kidney impairment or mild liver disease. Dosage adjustments may be necessary. Patients with a history of gout should use this medicine carefully, as it may affect uric acid levels.

Special Dietary and Lifestyle Recommendations

  • Maintain a low-sodium diet to help control blood pressure levels; processed foods high in salt should be avoided.

  • Regular aerobic exercise such as brisk walking, swimming, or cycling can help lower and manage blood pressure effectively.

  • Avoid excessive consumption of alcohol, as it can raise your blood pressure and reduce the effectiveness of this medication.

Frequently asked questions

No, Chlorthalidone + Olmesartan Medoxomil is not a steroid. It is a combination medication containing a diuretic (chlorthalidone) and an angiotensin II receptor blocker (olmesartan medoxomil).

Chlorthalidone + Olmesartan Medoxomil does not have any specific impact on sleep. However, if you notice any changes in your sleep patterns after starting this medication, please discuss it with your doctor.

There are no known effects of Chlorthalidone + Olmesartan Medoxomil on fertility. If you have concerns about fertility, it would be best to consult your doctor.

No specific dietary restrictions are required while on Chlorthalidone + Olmesartan Medoxomil. However, maintaining a healthy diet is generally beneficial for managing high blood pressure.

Yes, it is generally safe to take Chlorthalidone + Olmesartan Medoxomil daily if prescribed by your doctor for managing high blood pressure.

The blood pressure lowering effect of Chlorthalidone + Olmesartan Medoxomil usually begins within one week, with the full effect reached after 2-4 weeks of starting treatment.

Chlorthalidone + Olmesartan Medoxomil can be taken at any time of the day, but it is recommended to take it at the same time each day for optimal effect.

Terms & Conditions


Available medicines for CHLORTHALIDONE + OLMESARTAN MEDOXOMIL
Olmezest Ch 20 Tablet 10
Olmezest Ch 20 Tablet 10
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₹135.09
MRP ₹164.75
18.00% OFF
Olmo Ct Tablet 10
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₹162.92
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50.10% OFF
Omnipres Ch Tablet 10
Omnipres Ch Tablet 10
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₹51.90
MRP ₹104.00
50.10% OFF
Olmezest Ch 40 Tablet 10
Olmezest Ch 40 Tablet 10
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Pack of 10 Units
₹232.88
MRP ₹284.00
18.00% OFF
Olkem 40 Ct Tablet 10
Olkem 40 Ct Tablet 10
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Pack of 10 Units
₹237.80
MRP ₹290.00
18.00% OFF
Olmesar Ch 40 Tablet 15
Olmesar Ch 40 Tablet 15
Macleods Pharmaceuticals Pvt.ltd
Pack of 15 Units
₹333.74
MRP ₹407.00
18.00% OFF
Olmesar Ch 20 Tablet 15
Olmesar Ch 20 Tablet 15
Macleods Pharmaceuticals Pvt.ltd
Pack of 15 Units
₹186.71
MRP ₹227.70
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Olmetime Ct 40 Tablet 10
Olmetime Ct 40 Tablet 10
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₹132.06
MRP ₹161.05
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