Chlorthalidone + Ramipril
Uses of Chlorthalidone + Ramipril
Chlorthalidone + Ramipril is primarily used to manage hypertension or high blood pressure. It belongs to a group of medicines known as antihypertensive medications.
Secondary uses of this medication include the prevention of heart failure, stroke and kidney problems.
Side effects of Chlorthalidone + Ramipril
Dizziness or lightheadedness
Mild headache
Fatigue or weakness
Upset stomach
Nausea
Vomiting
How Chlorthalidone + Ramipril works
Chlorthalidone is a diuretic, or "water pill." It increases the amount of urine produced, helping to eliminate excess salt and water from your body. This process reduces the volume of blood that needs to be pumped around, which lowers your blood pressure.
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor. It blocks the formation of a substance called angiotensin II in your body. Angiotensin II causes blood vessels to tighten and narrow. By blocking its formation, Ramipril helps to relax and widen your blood vessels, making it easier for blood to flow through. This reduces the workload on your heart and lowers your blood pressure.
Working together, these two active ingredients manage high blood pressure effectively and reduce the risk of heart attack, stroke, and kidney disease associated with hypertension.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Chlorthalidone + Ramipril is available for oral use as tablets.
Age and Dose Restrictions
This combination medicine is intended for use in adults and is not recommended for children or adolescents.
Contraindications
Chlorthalidone + Ramipril is contraindicated in patients with known hypersensitivity to either of the active ingredients or other ACE inhibitors. It should not be used in patients with severe liver disease or significant renal impairment.
Other Medications to Avoid
Chlorthalidone + Ramipril may interact with diuretics (e.g., furosemide, spironolactone), other blood pressure lowering medicines (e.g., amlodipine, metoprolol), non-steroidal anti-inflammatory medications (NSAIDs) (e.g., ibuprofen or naproxen), and medications containing lithium.
Overdose and Missed Dose
Overdosing on Chlorthalidone + Ramipril can lead to very low blood pressure, electrolyte imbalances, and potential kidney failure. If an overdose is suspected, seek immediate medical attention.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double up on doses to compensate for the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medication. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
If you are experiencing dizziness while standing up from a lying or sitting position, try getting up slowly.
In case of fatigue or weakness, make sure to rest and sleep adequately.
For increased urination, try scheduling your doses so that you do not have to wake up at night to urinate.
Use in Driving and Operating Machinery
As Chlorthalidone + Ramipril may cause dizziness, it could potentially affect your ability to drive or operate heavy machinery. If you feel dizzy or aren't feeling well, avoid such activities until you feel better.
Use in Pregnancy and Lactation
It is recommended to consult your doctor before using Chlorthalidone + Ramipril during pregnancy and breastfeeding, as the safety of this medication in these conditions is not well established.
Caution in Other Conditions
Patients with kidney disease, liver disease, lupus, scleroderma, gout, diabetes, or electrolyte imbalances should use Chlorthalidone + Ramipril with caution.
Special Dietary and Lifestyle Recommendations
Maintain a low-sodium diet as this can help control high blood pressure.
Drink adequate amounts of water to prevent dehydration from increased urine output.
Regular medical check-ups are recommended while on this medication.
Frequently asked questions
Is Chlorthalidone + Ramipril a steroid?
No, Chlorthalidone + Ramipril is not a steroid. It is a combination medication used to manage high blood pressure. It contains Chlorthalidone, a diuretic, and Ramipril, an angiotensin-converting enzyme (ACE) inhibitor.
Does Chlorthalidone + Ramipril affect sleep?
Chlorthalidone + Ramipril does not generally affect sleep. However, some people may experience dizziness or lightheadedness, which could potentially disrupt sleep. If you experience any changes in your sleep patterns, you should consult your doctor.
Does Chlorthalidone + Ramipril impact fertility?
There is no evidence to suggest that Chlorthalidone + Ramipril impacts fertility in men or women. However, if you have concerns about fertility, it is important to discuss them with your doctor.
Are there vegan-friendly versions of Chlorthalidone + Ramipril?
Most medicines including Chlorthalidone + Ramipril are generally considered vegan-friendly. However, if you have specific dietary needs or preferences, such as a vegan diet, it is a good idea to discuss this with your doctor or pharmacist.
Can I take Chlorthalidone + Ramipril if I have gout?
If you have gout, you should discuss this with your doctor before taking Chlorthalidone + Ramipril. This medicine may increase uric acid levels in the blood which can trigger gout attacks.
Can I take Chlorthalidone + Ramipril if I am experiencing diarrhoea or vomiting?
If you are experiencing diarrhoea or vomiting, it may affect how your body absorbs and processes Chlorthalidone + Ramipril. It is essential you speak to your doctor if you are unwell.
Can I take a potassium supplement while using Chlorthalidone + Ramipril?
Taking a potassium supplement while using Chlorthalidone + Ramipril may cause high levels of potassium in your blood, which can be harmful. Always consult your doctor before starting any new medication, including over-the-counter supplements.
Chlorthalidone + Ramipril in other salts
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