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Chlorzoxazone + Nimesulide + Paracetamol/acetaminophen

Uses of Chlorzoxazone + Nimesulide + Paracetamol/acetaminophen

  • Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen is primarily used to manage acute musculoskeletal pain and inflammation. It belongs to the class of muscle relaxants and nonsteroidal anti-inflammatory medications.

  • It is also prescribed for acute low back pain, neck pain and spasms, sprains, strains, osteoarthritis flares, and post-operative or post-traumatic pain.

Side effects of Chlorzoxazone + Nimesulide + Paracetamol/acetaminophen

  • Drowsiness

  • Dizziness

  • Nausea

  • Vomiting

  • Skin rash or itching

How Chlorzoxazone + Nimesulide + Paracetamol/acetaminophen works

  • Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen is a combination pain reliever.

  • Chlorzoxazone is a muscle relaxant. It works on specific areas of the brain and the spinal cord to reduce muscle spasms.

  • Nimesulide is an NSAID or anti-inflammatory medicine. It reduces prostaglandin production, a substance that causes inflammation and pain, by inhibiting the enzyme cyclooxygenase-2 (COX-2).

  • Paracetamol/Acetaminophen is an analgesic and antipyretic. It likely blocks the transmission of pain signals to the brain and reduces fever by acting on the centre of the brain that regulates body heat.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen is available for use through the oral route in the form of tablets.

Age and Dose Restrictions

  • This medication is intended for adults only. It is not recommended for use in children and adolescents.

Contraindications

  • Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen is contraindicated in patients with known allergies to any of the active ingredients or excipients in the medicine.

  • It is also contraindicated in patients with severe hepatic or renal impairment, active or recurrent peptic ulcers or gastrointestinal bleeding.

Other Medications to Avoid

  • This combination may interact with anticoagulants (such as warfarin and heparin), corticosteroids (like prednisolone and dexamethasone), selective serotonin reuptake inhibitors (such as fluoxetine and sertraline), diuretics (like furosemide and hydrochlorothiazide), and antiepileptics (such as carbamazepine and phenytoin).

  • Always consult your doctor before starting any other prescription or over-the-counter medications to avoid potential interactions.

Overdose and Missed Dose

  • An overdose of Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen may lead to serious health complications, such as nausea, vomiting, abdominal pain, drowsiness, sweating, coma, and liver damage. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage side effects such as nausea and vomiting.

  • If you experience dizziness or light-headedness, it may help to lie down until these symptoms pass.

Use in Driving and Operating Machinery

  • Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen may cause drowsiness or dizziness. Avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

  • This medication is not recommended for use in pregnant and breastfeeding women, unless advised by a doctor. Always consult your doctor before using this medicine during pregnancy or lactation.

Caution in Other Conditions

  • Patients with severe hepatic or renal impairment should use Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen with caution, due to potential risks associated with this medication.

Special Dietary and Lifestyle Recommendations

  • A balanced diet, rich in fruits, vegetables, lean proteins and whole grains can improve overall health and support recovery from musculoskeletal conditions.

  • Regular gentle exercise such as walking, swimming or yoga can help improve muscle strength and flexibility. It is advisable to perform these activities under the guidance of a physiotherapist or healthcare professional.

  • Adequate rest and sleep are important for recovery from musculoskeletal pain and inflammation. Try to maintain a regular sleep schedule and create a comfortable sleeping environment.

  • Avoid smoking and limit alcohol intake as these can exacerbate inflammation and delay healing.

Frequently asked questions

No, Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen is not known to cause dependency or addiction. However, it should be used only as prescribed by your doctor.

Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen does not typically affect mood or behaviour. However, some people might experience drowsiness or dizziness, which could impact their daily activities.

There might be natural methods like physical therapy or certain exercises that can help manage musculoskeletal pain and inflammation. However, these should not replace the medicine unless advised by your doctor.

This medication is typically used for short durations, and stopping it suddenly should not cause withdrawal symptoms. Yet, it's always recommended to follow your doctor's advice regarding the duration of use.

If you have a known allergy to non-steroidal anti-inflammatory drugs (NSAIDs) such as nimesulide, you should not take this combination. Consult your doctor for alternative medicines.

No, Chlorzoxazone + Nimesulide + Paracetamol/Acetaminophen does not interfere with the hormonal balance in your body.

Elderly patients may be more sensitive to the side effects of this medicine. Therefore, it should be used under the supervision of a doctor, who can adjust the dosage as necessary.

Terms & Conditions


Chlorzoxazone + Nimesulide + Paracetamol/acetaminophen in other salts

ACECLOFENAC + PARACETAMOL/ACETAMINOPHENACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHENPARACETAMOL/ACETAMINOPHENIBUPROFEN + PARACETAMOL/ACETAMINOPHENNIMESULIDE + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + DICLOFENAC + PARACETAMOLACECLOFENAC + PARACETAMOL + CHLORZOXAZONENIMESULIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + RABEPRAZOLENIMESULIDE + TIZANIDINEDEXTROPROPOXYPHENE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + NIMESULIDELORNOXICAM + PARACETAMOL/ACETAMINOPHENNIMESULIDE + SERRATIOPEPTIDASENIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINECPM + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATEMETOCLOPRAMIDE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRAMADOLCHLORZOXAZONE + PARACETAMOL/ACETAMINOPHENCAFFEINE + IBUPROFEN + PARACETAMOL/ACETAMINOPHENCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORZOXAZONE + NIMESULIDEPARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE
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