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Ciprofloxacin + Ornidazole

Uses of Ciprofloxacin + Ornidazole

  • Ciprofloxacin + Ornidazole is used to treat or prevent certain infections caused by bacteria and parasites (amoeba). 
  • This combination belongs to the fluoroquinolone and nitroimidazole classes, offering broad-spectrum activity against various infections.
  • It is effective for treating diarrhoea, as well as managing mixed infections such as pelvic inflammatory disease and intra-abdominal infections. 
  • Additionally, it treats dental infections involving the teeth and gums, as well as vaginal and other bacterial infections.

Side effects of Ciprofloxacin + Ornidazole

  • Nausea

  • Vomiting

  • Abdominal discomfort

  • Diarrhoea or constipation

  • Rash and itching

How Ciprofloxacin + Ornidazole works

  • Ciprofloxacin + Ornidazole are antibacterial agents.

  • Ciprofloxacin, a fluoroquinolone antibiotic, works by blocking the enzymes DNA gyrase and topoisomerase IV. These enzymes are crucial for the replication of bacterial DNA and cell division. By inhibiting these enzymes, Ciprofloxacin destroys bacterial cells.

  • Ornidazole is a nitroimidazole antibiotic that specifically targets anaerobic bacteria and parasites. It enters the bacterial or parasitic cell, where it is reduced by cellular enzymes, creating reactive intermediates. These interventions damage the cell's DNA, leading to its death.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ciprofloxacin + Ornidazole can be taken orally (tablets and suspensions).

Age and Dose Restrictions

  • This combination is indicated for adults and children aged 12 years and older.

Contraindications

  • Ciprofloxacin + Ornidazole is contraindicated in individuals with known hypersensitivity to Ciprofloxacin, Ornidazole, or any other quinolone or nitroimidazole antibiotics.
  • The combination should not be used by individuals with a history of seizures, epilepsy, kidney or liver disease, myasthenia gravis (a neuromuscular disorder), prolonged QT interval, or other heart rhythm disorders.

Other Medications to Avoid

  • This combination may interact with antacids (such as aluminium hydroxide and magnesium hydroxide), iron supplements (like ferrous sulfate and ferrous gluconate), multivitamins containing zinc or calcium (such as ferrous fumarate and ferrous gluconate), anticoagulants (like warfarin), and certain immunosuppressants (like cyclosporine).

Overdose and Missed Dose

  • In the event of an overdose of Ciprofloxacin + Ornidazole, it is recommended to seek medical attention immediately.
  • If a dose is missed, take the medication as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with the usual schedule.

Management of Side Effects

Most adverse effects are temporary, generally harmless, and resolve after stopping this medicine. However, if you experience any severe adverse effects or worsening of any of the symptoms, it is recommended that you consult your doctor.

  • Drinking plenty of fluids can help manage side effects such as nausea and vomiting.
  • Rest and avoiding sudden movements can help manage dizziness.

Use in Driving and Operating Machinery

  • Ciprofloxacin + Ornidazole may cause dizziness. Avoid driving, operating heavy machinery, or performing any activities requiring mental alertness if you experience this side effect.

Use in Pregnancy and Lactation

  • It is generally not recommended to use Ciprofloxacin + Ornidazole during pregnancy and breastfeeding. However, a doctor can best advise on its use during these periods based on the condition of an individual.

Caution in Other Conditions

  • Patients with kidney or liver disease should take Ciprofloxacin + Ornidazole with caution, as the medicine is metabolised in the liver and excreted through the kidneys.

Special Dietary and Lifestyle Recommendations

  • Regular hand hygiene can help prevent the spread of bacterial infections.
  • Some people may experience gastrointestinal side effects. Consider taking probiotics or eating yoghurt to help gastrointestinal side effects.
  • Finish the full course of this combination as prescribed by your doctor even if you start feeling better. Stopping early can lead to incomplete treatment and antibiotic resistance.

Frequently asked questions

No, Ciprofloxacin + Ornidazole is not a steroid. It is a combination of two antibiotics used to manage various bacterial and parasitic infections.

The medicine is not known to affect sleep. If you experience sleep disturbances, consult your doctor.

Ciprofloxacin + Ornidazole doesn't typically affect fertility. However, if you are concerned about the effect of this medicine on fertility, consult your doctor for personalised advice.

Ciprofloxacin + Ornidazole are usually taken as prescribed by the doctor, depending on the type and severity of the infection. It is advised to always follow your doctor's instructions regarding dosage and duration of treatment.

You may start to feel better within a few days of starting treatment. However, it is essential to complete the entire course of the medicine as prescribed by the doctor, even if symptoms improve.

Ciprofloxacin + Ornidazole can be taken at any time of the day, with or without food. However, dairy products and calcium-fortified juices should be avoided within 2 hours before or 6 hours after taking Ciprofloxacin.

While some natural remedies may help support the immune system, they cannot replace the action of antibiotics like Ciprofloxacin + Ornidazole. It is advised to always consult your doctor before starting any alternative or complementary treatments.

Terms & Conditions


Available medicines for CIPROFLOXACIN + ORNIDAZOLE
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Floxip Oz 500/500 MG Tablet 10
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