Clarithromycin + Lansoprazole + Tinidazole

Dosage Forms Available

• Clarithromycin + Lansoprazole + Tinidazole can be taken orally (tablet).

Age and Dose Restrictions

• This medicine is meant for use in adults.

Contraindications

• This combination is contraindicated in patients with known hypersensitivity to any of its components. It is also contraindicated for those taking cisapride, pimozide, astemizole, terfenadine, ergotamine, or dihydroergotamine due to potential adverse reactions with clarithromycin. Additionally, the use of lansoprazole is contraindicated with rilpivirine.

Other Medications to Avoid

• This combination may interact with several medications, including other antibiotics (such as erythromycin), antacids (like magnesium hydroxide), and anticoagulants (such as warfarin).

Overdose and Missed Dose

• An overdose may result in severe gastrointestinal effects, such as nausea or vomiting, as well as neurological symptoms like dizziness and headaches. If you suspect an overdose, it is vital to seek immediate medical attention.

• If you miss a dose of Clarithromycin + Lansoprazole + Tinidazole, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose to avoid doubling up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage a metallic taste which may occur due to tinidazole, consider chewing sugar-free gum or brushing your teeth more frequently.

• If experiencing mild gastrointestinal symptoms like nausea or diarrhoea, try taking your medicine with food or increasing your intake of water.

Use in Driving and Operating Machinery

• Clarithromycin + Lansoprazole + Tinidazole may cause dizziness or confusion. It is prudent to avoid driving or operating heavy machinery if you experience these symptoms after taking the medication.

Use in Pregnancy and Lactation

• It is advised to consult your doctor before using Clarithromycin + Lansoprazole + Tinidazole during pregnancy and breastfeeding. The safety of this medication for use in these conditions has not been fully established.

Caution in Other Conditions

• Caution is advised when administering Clarithromycin + Lansoprazole + Tinidazole to patients with liver or kidney impairment. Adjustments in dosage may be necessary based on individual health status.

Special Dietary and Lifestyle Recommendations

• To support treatment for H. pylori infection, maintain a balanced diet rich in fibre such as fruits and vegetables which can aid digestion and help manage stomach acid levels.

• Avoid foods that can irritate the stomach lining such as spicy foods, citrus fruits, chocolate, and caffeinated beverages.

• Limit alcohol consumption as it can increase stomach acidity and may interfere with the effectiveness of tinidazole.

• Stress management techniques such as yoga, meditation, or regular exercise can help reduce stress which may exacerbate stomach ulcers.

• Maintaining a regular eating schedule can also help manage symptoms by reducing the chances of significant fluctuations in stomach acid throughout the day.