The primary use of Clobetasone + Gentamicin + Miconazole is to manage varied skin conditions that involve inflammation, bacterial infection, and/or fungal infection. This medicine belongs to the group of corticosteroids, antibiotics, and antifungal medications.
This combination is also useful in managing inflamed skin conditions like dermatitis or eczema, intertrigo (rash/inflammation in skin folds), otitis externa (outer ear infection), and minor skin infections showing signs of inflammation.
Local skin irritation or redness
Itching or burning sensation
Skin dryness or peeling
Skin lightening in the treated area
Allergic reactions like rash or hives (rarely)
Clobetasone + Gentamicin + Miconazole is a combination medicine with anti-inflammatory, antibacterial, and antifungal activities.
Clobetasone is a corticosteroid. It works by activating certain proteins within skin cells that reduce inflammation, itching, and redness. It also causes small blood vessels to narrow, further reducing swelling and redness.
Gentamicin is an antibiotic. It works by attaching to bacteria's protein-making machinery, disrupting their ability to make essential proteins. This kills the bacteria or slows their growth, helping to eliminate the bacterial infection.
Miconazole is an antifungal agent. It stops fungi from producing a substance called ergosterol. This disruption makes holes in the fungal cell membranes, causing essential cell contents to leak out. This effectively kills the fungi, clearing up the infection.
Overall, this combination medication effectively treats inflammatory skin conditions with bacterial and fungal infections by leveraging its anti-inflammatory, antibacterial, and antifungal properties.
MSc (Applied Genetics)
BMS, FMC, MD Resident
Clobetasone + Gentamicin + Miconazole is available for use via topical route in the form of cream, ointment, and lotion.
This medicine is intended for adult use only.
Clobetasone + Gentamicin + Miconazole is contraindicated in patients with known allergies to any of the three active ingredients. It is also contraindicated in patients with viral skin infections, certain bacterial infections, and fungal infections not susceptible to miconazole.
This combination may interact with neuromuscular blocking agents (such as succinylcholine), anticoagulants (like warfarin), medications that may cause heart rhythm disturbances (such as amiodarone), and medicines inhibiting the metabolism of steroids (like macrolide antibiotics).
An overdose of this medication may cause skin symptoms like redness, itching, peeling, or burning. If you observe these symptoms, inform your doctor immediately.
If you forget to apply this medication, do it as soon as you remember. But avoid applying double amounts to make up for the missed application.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For mild skin irritation or dryness, consider reducing the frequency of application.
If a severe rash or allergic reaction occurs, discontinue use and consult your doctor.
As a topical medication, Clobetasone + Gentamicin + Miconazole does not affect your ability to drive or operate heavy machinery.
It's advised to consult your doctor before using this medicine during pregnancy or while breastfeeding.
Patients with severe skin damage or open wounds should exercise caution when using this medicine.
Maintain good skin hygiene to avoid further bacterial or fungal infections.
Avoid excessive exposure to sunlight as it may aggravate the condition being managed by this medicine.
Keep the treated area clean and dry, except when applying the medicine.
Avoid scratching or rubbing the treated areas to avoid further skin damage.
Frequently asked questions
Yes, Clobetasone is a type of steroid known as a corticosteroid. However, this combination also includes Gentamicin, an antibiotic, and Miconazole, an antifungal agent.
There is no known direct effect of this topical medication on sleep cycles. However, managing itching and inflammation associated with skin conditions may indirectly improve sleep quality.
There is no specific data suggesting that this combination affects human fertility. However, prolonged and extensive use should be avoided, especially without medical supervision.
As this medication is applied topically rather than taken orally, it should not interact with alcohol. However, you should always consult your doctor about any potential interactions.
It is generally not recommended to use this medication for longer than two weeks at a time due to the risk of side effects like skin thinning and antimicrobial resistance. You should always follow your doctor's advice about the duration of use.
This combination can be used on the face but should be applied cautiously because the skin on the face is thinner and more sensitive than other parts of the body. Prolonged use can lead to skin thinning and other adverse effects.
Yes, but it should be used cautiously in children as they may absorb proportionally larger amounts. Always consult a doctor before giving any medication to a child.
Clobetasone + Gentamicin + Miconazole in other salts
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