Clomifene + Coenzyme Q10 / Ubidecarenone

Dosage Forms Available

• Clomifene is available for use orally in the form of tablets.
• Coenzyme Q10 / Ubidecarenone is available as a dietary supplement to be consumed orally in the form of capsules or tablets.

Age and Dose Restrictions

• The use of Clomifene + Coenzyme Q10 / Ubidecarenone is intended for adults only.
• It is not recommended for use in children or adolescents under the age of 18 years.

Contraindications

• Clomifene + Coenzyme Q10 / Ubidecarenone is contraindicated in patients with known hypersensitivity to either clomifene or Coenzyme Q10 / Ubidecarenone.
• It should not be used by patients suffering from liver disease, uncontrolled thyroid or adrenal dysfunction, and ovarian cysts or enlarged ovaries not due to Polycystic ovary syndrome (PCOS).

Other Medications to Avoid

• This combination may interact with oestrogens and oral contraceptives (such as ethinyl estradiol and levonorgestrel), progestins (like progesterone) and, thyroid medicines (such as levothyroxine and liothyronine).
• It can also interact with anticoagulants or blood thinners (like warfarin), insulin and diabetes medicines (like metformin and glipizide), doxorubicin and other chemotherapy medicines, and blood pressure medications (such as losartan and valsartan).

Overdose and Missed Dose

• In case of an overdose of Clomifene + Coenzyme Q10 / Ubidecarenone, please seek immediate medical attention. Overdose may cause visual disturbances, nausea, vomiting, breast tenderness, and uterine bleeding.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time of your next dose, then skip the missed dose. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage some side effects such as nausea and vomiting.
• Resting in a dark and quiet room may help manage visual disturbances

Use in Driving and Operating Machinery

• As Clomifene + Coenzyme Q10 / Ubidecarenone may cause visual disturbances, it may affect your ability to drive or operate heavy machinery. Avoid these activities if you experience these side effects.

Use in Pregnancy and Lactation

• Clomifene + Coenzyme Q10 / Ubidecarenone is not recommended during pregnancy and breastfeeding. Always consult your doctor before using this combination during these stages.

Caution in Other Conditions

• Patients with liver disease, and uncontrolled thyroid or adrenal dysfunction should exercise caution when taking Clomifene + Coenzyme Q10 / Ubidecarenone.
• Also, patients with ovarian cysts or enlarged ovaries not due to PCOS should use this combination with caution.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet rich in antioxidants to support the action of Coenzyme Q10 / Ubidecarenone. Include fruits, vegetables, nuts, and seeds in your diet.
• Regular physical activity can aid in managing PCOS and improving fertility.
• Maintain a healthy body weight. Obesity can worsen PCOS symptoms and make fertility treatments less effective.
• Limit consumption of processed foods and sugary beverages. These can contribute to inflammation and worsen hormonal imbalances in PCOS.