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Clopidogrel

ANTIPLATELET

Uses of Clopidogrel

  • Clopidogrel is used to prevent serious life-threatening events like stroke, and myocardial infarction in patients with established cardiovascular disease.
  •  It is also used in patients who have undergone percutaneous coronary intervention ( coronary stent insertion) and coronary artery bypass grafting to prevent the formation of clots and occlusion of the stent or the vessels used for the bypass.
  • It is also used to prevent serious life-threatening events (due to thrombus or embolus formation) like stroke and myocardial infarction in patients with peripheral arterial disease and atrial fibrillation.

Side effects of Clopidogrel

  • Bleeding- Hematoma, epistaxis (nose bleed), gastrointestinal bleeding, bruising
  • Diarrhoea
  • Abdominal pain
  • Heartburn 

How Clopidogrel works

  • Clopidogrel is an antiplatelet medication.
  • It acts by inhibiting the ADP-mediated activation of platelets and thereby prevents the formation of clots. which can cause thrombosis and lead to life-threatening events like stroke or myocardial infarction.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Clopidogrel is available for use via oral (Tablet) route.

Age And Dose Restrictions

  • It is meant for use by adults only.

Contraindications 

  • Clopidogrel is contraindicated in patients who are hypersensitive to it, have severe liver dysfunction and active pathological bleeding conditions like peptic ulcer or intracranial haemorrhage (bleeding in the cranial cavity)

Medications To Avoid With This Drug

  • Medications which may increase the risk of bleeding like anticoagulants, aspirin, and heparin should be avoided while taking Clopidogrel.

Overdose And Missed Dose

  • If a dose is missed, it should be taken if there is a time gap from the subsequent dose. If not, then a routine dosing regimen should be followed
  • Overdose of clopidogrel can cause bleeding complications and need to be managed urgently in a hospital setting by platelet transfusion.

Management Of Side Effects

  • Take this medicine with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This medicine can cause dizziness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking this medicine. 

Use In Pregnancy And Lactation

  • It is not recommended to be used in Pregnant and lactating females.

Caution In Other Conditions

  • Caution is advised for its use in patients with Liver and kidney disease. Special precaution is advised for patients who have bleeding disorders like acquired thrombophilia, TTP, etc as clopidogrel use can aggravate these conditions.

Special Dietary And Lifestyle Recommendation

  • Alcohol consumption should be avoided when using clopidogrel.

Frequently asked questions

Clopidogrel is not advised to be taken in pregnancy. Consult your doctor for further advice.

Clopidogrel begins its action within two hours. However, it varies from individual to individual.

Clopidogrel is not advised to be taken in breastfeeding mothers. Consult your doctor for further advice.

The warnings and precautions to be followed while taking clopidogrel are; Patients with bleeding disorders like thrombophilia and those with active bleeding disorders should avoid taking this medicine, and Since this medicine is known to cause bleeding, patients should be vigilant about this effect and inform the doctor at the earliest if such a symptom manifests.

No. Clopidogrel should be taken for the prescribed duration.

Fertility is unlikely to be affected by clopidogrel.

Yes. Clopidogrel increases the risk of bleeding and the patient is advised to stay vigilant while using it.

Terms & Conditions


Available medicines for CLOPIDOGREL
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