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Dapsone

Uses of Dapsone

  • The primary use of Dapsone is for the management of skin conditions like dermatitis herpetiformis and leprosy (Hansen's disease), and it belongs to the class of sulfone antibacterial medicines.

  • Additionally, in certain cases where other treatments have not been effective, Dapsone may be prescribed for severe acne.

Side effects of Dapsone

  • Site dryness and pruritus (topical)

  • Nausea and vomiting

  • Headache

  • Stomach upset

How Dapsone works

  • Dapsone is an antibacterial medication of the sulfone class.

  • It functions by interfering with the growth of bacteria. This is accomplished by blocking the synthesis of folic acid, an essential component for bacteria to survive and multiply. By interrupting the production of folic acid, Dapsone prevents bacterial growth, helping to manage infections effectively.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Dapsone is available in the form of oral tablets.
  • It is also used as a topical gel.

Age and Dose Restrictions

  • This medicine is meant for use in adults and potentially teens based on doctor's advice.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to Dapsone or any component of the formulation.
  • It is contraindicated in patients with severe anaemia.
  • It is contraindicated in patients with severe G6PD deficiency.

Other Medications to Avoid

  • Dapsone may interact with other antibiotics such as rifampicin, which can decrease Dapsone levels, and trimethoprim (like proloprim), which may increase the risk of adverse haematologic reactions.
  • It may also interact with gout medications (like probenecid), which may increase Dapsone levels, and folic acid supplements (like levomefolate), as Dapsone can decrease folic acid levels.

Overdose and Missed Dose

  • Symptoms of an overdose of Dapsone include nausea, vomiting, abdominal pain, and agitation. Please contact your doctor if you notice any overdose symptoms.
  • If you miss a dose of Dapsone, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

  • If experiencing nausea or headache, consider taking the medicine with food.
  • If mild rashes occurs, monitor it to ensure it does not worsen; apply cool compresses if irritation occurs.

Use in Driving and Operating Machinery

  • Dapsone does not generally affect your ability to drive or operate machinery. However, be mindful of how you feel while taking it as individual reactions can vary.

Use in Pregnancy and Lactation

  • Use during pregnancy or while breastfeeding should only be considered if clearly needed. Both neonatal haemolytic anaemia and jaundice have been associated with its use. Consult your doctor before using this medicine during pregnancy or lactation.

Caution in Other Conditions

  • Patients with mild to moderate G6PD deficiency should use this medicine with caution.
  • Patients with a history of methemoglobinemia should avoid dapsone, as it can increase the risk of methemoglobin formation, leading to oxygen transport issues.
  • Caution should also be exercised in patients with cardiac disease, pulmonary disease, liver impairment, or renal impairment.

Special Dietary and Lifestyle Recommendations

  • Ensure a balanced diet rich in folic acid due to Dapsone’s potential effect on folic acid levels; consider foods like leafy greens, oranges, and whole grains.
  • It might be helpful to avoid excessive sunlight or use protective clothing and sunscreen, as some users could experience increased sensitivity to sunlight while taking this medicine.
  • For those managing leprosy or dermatitis herpetiformis using Dapsone, stress management techniques such as yoga or meditation could be beneficial to overall well-being and disease management.

Frequently asked questions

No, Dapsone is not a steroid. It is an antibacterial medication belonging to the sulfone class.

There is no documented evidence to suggest that Dapsone has any direct impact on sleep. However, some side effects such as headaches could indirectly affect sleep.

There is no scientific evidence indicating that Dapsone has any effects on fertility. However, it is always best to consult your doctor if you have concerns regarding this matter.

No specific dietary restrictions are required while taking Dapsone, but it should be taken with food to minimise gastrointestinal side effects.

Yes, it can be safe to take Dapsone daily when used under the supervision of a doctor, and as prescribed.

The time taken by Dapsone to show its effect may vary depending on the individual and the condition being managed.

The best time to take Dapsone will be prescribed by your doctor.

Terms & Conditions

Available medicines for DAPSONE
Dapsone Tablet 1000
Dapsone Tablet 1000
Glaxosmithkline Pharmaceuticals Ltd.
Pack of 1000 Units
₹353.01
MRP ₹430.50
18.00% OFF
Acnedap Gel 15gm
Acnedap Gel 15gm
Cipla Ltd.
Pack of 15 GM
₹397.09
MRP ₹481.85
17.59% OFF
Acnewar Gel 15gm
Acnewar Gel 15gm
Akumentis Healthcare Ltd
Pack of 15 GM
₹236.16
MRP ₹288.00
18.00% OFF
Acnesone 5% Gel 20gm
Acnesone 5% Gel 20gm
Systopic Laboratories Private Limited
Pack of 20 GM
₹38.64
MRP ₹47.12
18.00% OFF

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